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Gastric bypass shows slight edge over sleeve gastrectomy in long-term study

The long-term weight loss effects of sleeve gastrectomy and Roux-en-Y gastric bypass in people with obesity.

25 Jan 2024

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness.

24 Jan 2024

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature Medicine.

24 Jan 2024

Genomics meets retinal imaging: A powerful fusion can predict future health

The retina is said to provide a window into a person's systemic health. In a new study published January 24th in Science Translational Medicine, physician-researchers from Mass Eye and Ear, a member of Mass General Brigham, and the Broad Institute of MIT and Harvard combined retinal imaging, genetics and big data to estimate how likely a person is to develop eye and systemic diseases in the future.

24 Jan 2024

Researchers uncover a gene that causes heart defects in Down syndrome

Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21.

24 Jan 2024

New study illuminates the genetics of thumb arthritis treatment

Rhizarthrosis, also known as trapeziometacarpal osteoarthritis, is a type of osteoarthritis that affects the thumb, and treatments range from splints to surgery.

24 Jan 2024

In Los Angeles, occupational therapists tapped to help homeless stay housed

Carla Brown waits on an air mattress, eager for her occupational therapist to arrive at her apartment next to the Hollywood Freeway, mere blocks from where she once camped on the sidewalk.

24 Jan 2024

Combination drug therapy beats solo treatment for aggressive prostate cancer relapse

Combining testosterone-blocking drugs in patients with prostate cancer relapse prevents the spread of cancer better than treatment with a single drug, a multi-institution, Phase 3 clinical trial led by UC San Francisco researchers has found.

23 Jan 2024

Long-term prostate cancer treatment study informs decisions for diverse groups

A 10-year follow up study of nearly 2,500 U.S. men who received prostate cancer treatment will help inform decision making in terms of treatments and side effects for a diverse population.

23 Jan 2024

AI model accurately predicts lymph node metastasis in nonfunctional pancreatic neuroendocrine tumors

Nonfunctional pancreatic neuroendocrine tumors, while rare, are primarily treated through surgery. The presence or absence of lymph node metastasis considerably influences the selection of surgical and other treatment approaches.

23 Jan 2024

The long-term outcomes of diabetes remission and its impact on health

Researchers examine the effect of diabetes remission on long-term health outcomes.

23 Jan 2024

Team approach to prostate cancer: PCPs and urologists offer hope with active surveillance

This study considers the perspectives of primary care physicians (PCPs) and urologists on what facilitates and what creates barriers to active surveillance (AS) care for men with low-risk prostate cancer.

22 Jan 2024

Revolutionary bio-sponge halts bleeding instantly

More than 11 million people in the United States take anticoagulation or antiplatelet medications, such as heparin or aspirin, to treat serious conditions like heart attack and stroke.

22 Jan 2024

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it's hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

22 Jan 2024

Study evaluates factors associated with selection of active surveillance for low-risk prostate cancer

Because low-risk prostate cancer is unlikely to spread or impact survival, experts and guidelines recommend active surveillance, which involves regular monitoring and thus avoid or delay treatment like surgery or radiation therapy and their life-changing complications.

22 Jan 2024