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New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Key proteins and pathways drive the success of CAR-T cell therapy

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

An Arm and a Leg: A mathematical solution for US hospitals?

What do the KGB and the former CEO of Cincinnati Children’s Hospital have in common?

4 Jun 2025

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

A randomized clinical trial found that low-dose lithium aspartate did not improve cognitive dysfunction or fatigue in long COVID patients. Higher doses showed possible benefits in a small exploratory substudy, but larger trials are needed.

4 Jun 2025

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

Early camizestrant therapy keeps advanced breast cancer in check

Switching to camizestrant, a next-generation oral SERD, significantly prolongs progression-free survival and maintains quality of life in patients with ESR1-mutated, hormone receptor-positive advanced breast cancer. The proactive, biomarker-guided approach allows earlier intervention and may redefine standard care.

3 Jun 2025

Whole-class mental health sessions in schools help reduce depression and anxiety

Whole-class mental health sessions in schools have a small but significant effect in reducing depression and anxiety symptoms, according to new analysis led by researchers at UCL (University College London) and Anna Freud.

3 Jun 2025

UC Irvine researchers uncover altered RNA processing in ALS

UC Irvine researchers conducted a study to better understand the molecular basis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder in which patients lose the ability to move, becoming weak and wheelchair bound before dying because they can no longer breathe.

3 Jun 2025

Transforming IBS treatment through psychedelic medicine

In a comprehensive Genomic Press Interview published today, Dr. Erin E. Mauney reveals how her pioneering research brings psychedelic medicine into gastroenterology for the first time, potentially transforming treatment for millions suffering from intractable irritable bowel syndrome (IBS).

3 Jun 2025

Study uncovers how HSV-1 disables the brain's antiviral defense

Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that inflames the brain.

3 Jun 2025

New study stands to improve the rigor and reliability of psychedelic clinical trials

As psychedelics gain traction as potential treatments for mental health disorders, an international study led by researchers at McGill University, Imperial College London, and the University of Exeter stands to improve the rigor and reliability of clinical research.

3 Jun 2025

THP regimen achieves high response rates in HER2 positive breast cancer patients

Patients with Stage II and III (early-stage) HER2+ breast cancer usually undergo pre-operative therapy with multi-agent chemotherapy in combination with anti-HER2 antibodies, followed by surgery.

2 Jun 2025

High-fiber plant-based diet could benefit patients at risk for developing multiple myeloma

Results from a new clinical trial suggest that a high-fiber plant-based diet could benefit patients at risk for developing multiple myeloma, the second most common type of blood cancer.

2 Jun 2025

First-in-class antibody-drug conjugate shows high response rates in rare blood cancer trial

The first-in-class antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) demonstrated promising efficacy and high response rates for patients with blastic plasmacytoid dendric cell neoplasm (BPDCN), according to data from a Phase I/II study led by researchers from The University of Texas MD Anderson Cancer Center.

2 Jun 2025

Immunotherapy before surgery boosts long term survival in lung cancer, trial shows

Results from a phase 3 clinical trial published in the New England Journal of Medicine, today (June 2nd) show that patients with lung cancer who received an immunotherapy drug, nivolumab, along with standard chemotherapy before surgery had improved long term survival compared to those who received chemotherapy alone, at 5 years after completing treatment.

2 Jun 2025

Engineered viruses and gene therapy halt tumor growth and extend survival in mice

This study reveals the potential of engineered phage-IL-12 therapy in melanoma, enhancing immune response and tumor destruction in aggressive cancer models.

2 Jun 2025

Multiple chatbots simulate group therapy to help women manage premenstrual syndrome

A research team has designed and implemented a group motivational interviewing system using multiple chatbots to support premenstrual syndrome (PMS), a common disorder among women.

2 Jun 2025

Terbium therapy shows promise in fighting lymphoma

Radionuclide therapy with the radioactive element terbium could effectively combat lymphoma. This is demonstrated by promising results from experiments carried out at the Paul Scherrer Institute PSI in collaboration with Inselspital - Bern University Hospital.

2 Jun 2025

Dual treatment strategy offers survival advantage for patients with severe heart disease

Aortic valve narrowing (aortic stenosis) with concomitant cardiac amyloidosis is a severe heart disease of old age that is associated with a high risk of death.

2 Jun 2025

New combination treatment offers hope for immune checkpoint blockade resistant skin cancers

A study has revealed why some patients don't respond to immune checkpoint blockade (ICB) therapy for solid cancer tumors and identifies a new combination treatment.

2 Jun 2025

Therapy News and Research

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Key proteins and pathways drive the success of CAR-T cell therapy

An Arm and a Leg: A mathematical solution for US hospitals?

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

Navigating the dual role of B cells in tumor immunity

Early camizestrant therapy keeps advanced breast cancer in check

Whole-class mental health sessions in schools help reduce depression and anxiety

UC Irvine researchers uncover altered RNA processing in ALS

Transforming IBS treatment through psychedelic medicine

Study uncovers how HSV-1 disables the brain's antiviral defense

New study stands to improve the rigor and reliability of psychedelic clinical trials

THP regimen achieves high response rates in HER2 positive breast cancer patients

High-fiber plant-based diet could benefit patients at risk for developing multiple myeloma

First-in-class antibody-drug conjugate shows high response rates in rare blood cancer trial

Immunotherapy before surgery boosts long term survival in lung cancer, trial shows

Engineered viruses and gene therapy halt tumor growth and extend survival in mice

Multiple chatbots simulate group therapy to help women manage premenstrual syndrome

Terbium therapy shows promise in fighting lymphoma

Dual treatment strategy offers survival advantage for patients with severe heart disease

New combination treatment offers hope for immune checkpoint blockade resistant skin cancers

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