Protein C News and Research

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Cedars-Sinai researchers develop unique imaging device to "light up" malignant brain tumors

Researchers at the Cedars-Sinai Maxine Dunitz Neurosurgical Institute and Department of Neurosurgery have developed a unique, compact, relatively inexpensive imaging device to "light up" malignant brain tumors and other cancers.

27 Feb 2014

Researchers discover new target for human antibodies that holds key to vaccine for dengue

Creating a vaccine that protects people from all four types of dengue virus has frustrated scientists for decades. But researchers at the University of North Carolina have discovered a new target for human antibodies that could hold the key to a vaccine for the world's most widespread mosquito-borne disease.

27 Feb 2014

Novel SCLC tumour suppressor gene discovered

Inactivation of the MYC-associated factor X gene, MAX, may play a significant role in the development of small-cell lung cancer, scientists believe.

26 Feb 2014

Prothelia and University of Nevada, Reno enter into agreements with Alexion for development of Laminin-111

Prothelia Incorporated (Prothelia) and University of Nevada, Reno announce that they have entered into strategic agreements with Alexion for the development of Laminin-111, a patented experimental protein replacement therapy for merosin-deficient congenital muscular dystrophy (MDC1A), a life-threatening, ultra-rare disease caused by a genetic deficiency of the Laminin-211 protein.

26 Feb 2014

Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

Protein M is a cell surface protein from Mycoplasma Genitalium that binds to all human antibodies.

26 Feb 2014

FDA approves KALYDECO for people with cystic fibrosis

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced the U.S. Food and Drug Administration (FDA) approved a supplemental New Drug Application (sNDA) for KALYDECOTM (ivacaftor) for people with cystic fibrosis (CF) ages 6 and older who have one of eight additional mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. KALYDECO was first approved in January 2012 for people with CF ages 6 and older who have at least one copy of the G551D mutation.

26 Feb 2014

New way to potentially block chronic pain affecting osteoarthritis sufferers

Researchers from the Arthritis Research UK Pain Centre at The University of Nottingham have discovered a new way to potentially block the chronic and often debilitating pain affecting osteoarthritis sufferers.

26 Feb 2014

Scales of zebrafish suitable for identifying new drugs for treating bone diseases

The scales of the zebrafish are very suitable for identifying potential new drugs for treating bone diseases. This is good news because it means fewer mice and rats will be needed for that work.

26 Feb 2014

Researchers develop new compound that slows down progression of Huntington's Disease

Juliet Ross is suffering from Huntington's Disease, a rare neurological disorder that affects one in 10.000 people. Due to a genetic defect, her body produces a toxic protein that damages neurons in her brain.

26 Feb 2014

New blood test can detect heart attacks hours faster than current gold-standard blood test

A new blood test can detect heart attacks hours faster than the current gold-standard blood test, according to a study led by Loyola University Chicago Stritch School of Medicine researchers.

26 Feb 2014

Engineers develop paper test that could improve diagnosis rates for cancer

Cancer rates in developing nations have climbed sharply in recent years, and now account for 70 percent of cancer mortality worldwide. Early detection has been proven to improve outcomes, but screening approaches such as mammograms and colonoscopy, used in the developed world, are too costly to be implemented in settings with little medical infrastructure.

26 Feb 2014

New optical device may help docs to diagnose blood coagulation status in near real time

Defective blood coagulation is one of the leading causes of preventable death in patients who have suffered trauma or undergone surgery. The body's natural defense against severe blood loss is the clotting process, in which platelets, plasma proteins, and other blood components interact to form a sticky, mesh-like structure.

26 Feb 2014

Research grows "mini-livers" to reduce use of animals in science

Research that has for the first time successfully grown "mini-livers" from adult mouse stem cells has won the UK's international prize for the scientific and technological advance with the most potential to replace, reduce or refine the use of animals in science (the 3Rs).

26 Feb 2014

Increased brain cell activity boosts protein linked to Alzheimer's disease

Increased brain cell activity boosts brain fluid levels of a protein linked to Alzheimer's disease, according to new research from scientists at Washington University School of Medicine in St. Louis.

26 Feb 2014

Scientists create 3-D elastic membrane that is precisely shaped to match heart's epicardium

Igor Efimov, PhD, at the School of Engineering & Applied Science at Washington University in St. Louis and an international team of biomedical engineers and materials scientists have created a 3-D elastic membrane made of a soft, flexible, silicon material that is precisely shaped to match the heart's epicardium, or the outer layer of the wall of the heart.

26 Feb 2014

Researcher isolates gene thought to play role in development of Alzheimer's disease

A team of international scientists, including a researcher from Simon Fraser University, has isolated a gene thought to play a causal role in the development of Alzheimer's disease. The Proceedings of the National Academy of Sciences recently published the team's study.

26 Feb 2014

Researcher identifies ''conductor'' in development of muscle tissue

A team led by Jean-Fran-ois C-t-, researcher at the IRCM, identified a ''conductor'' in the development of muscle tissue. The discovery, published online yesterday by the scientific journal Proceedings of the National Academy of Sciences (PNAS), could have an important impact on the treatment of muscular diseases such as myopathies and muscular dystrophies.

26 Feb 2014

Researchers produce extremely accurate and detailed images of "toxic injections"

Bacteria have developed many different ways of smuggling their toxic cargo into cells. Tripartite Tc toxin complexes, which are used by bacteria like the plague pathogen Yersinia pestis and the insect pathogen Photorhabdus luminescens, are particularly unusual.

25 Feb 2014

Active ingredient in vinegar can effectively kill mycobacteria

The active ingredient in vinegar, acetic acid, can effectively kill mycobacteria, even highly drug-resistant Mycobacterium tuberculosis, an international team of researchers from Venezuela, France, and the US reports in mBio-, the online open-access journal of the American Society for Microbiology.

25 Feb 2014

Study: Routine testing with FISH and IHC may enhance detection of ALK-positive NSCLC

The findings of a recent study indicate that routine testing with both fluorescent in situ hybridization (FISH) and immunohistochemistry (IHC) may enhance the detection of ALK-positive non-small cell lung cancer (NSCLC).

25 Feb 2014

Protein C News and Research

Cedars-Sinai researchers develop unique imaging device to "light up" malignant brain tumors

Researchers discover new target for human antibodies that holds key to vaccine for dengue

Novel SCLC tumour suppressor gene discovered

Prothelia and University of Nevada, Reno enter into agreements with Alexion for development of Laminin-111

Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

FDA approves KALYDECO for people with cystic fibrosis

New way to potentially block chronic pain affecting osteoarthritis sufferers

Scales of zebrafish suitable for identifying new drugs for treating bone diseases

Researchers develop new compound that slows down progression of Huntington's Disease

New blood test can detect heart attacks hours faster than current gold-standard blood test

Engineers develop paper test that could improve diagnosis rates for cancer

New optical device may help docs to diagnose blood coagulation status in near real time

Research grows "mini-livers" to reduce use of animals in science

Increased brain cell activity boosts protein linked to Alzheimer's disease

Scientists create 3-D elastic membrane that is precisely shaped to match heart's epicardium

Researcher isolates gene thought to play role in development of Alzheimer's disease

Researcher identifies ''conductor'' in development of muscle tissue

Researchers produce extremely accurate and detailed images of "toxic injections"

Active ingredient in vinegar can effectively kill mycobacteria

Study: Routine testing with FISH and IHC may enhance detection of ALK-positive NSCLC

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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