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Blunting emotional component associated with pain

Chronic pain involves more than just hurting. People suffering from pain often experience sadness, depression and lethargy. That's one reason opioids can be so addictive -- they not only dampen the pain but also make people feel euphoric.

13 Mar 2019

Avocado seed extract could be potential source for novel anti-inflammatory compounds

An extract from the seeds of avocados exhibited anti-inflammatory properties in a laboratory study, according to Penn State researchers, and it represents a potential source for novel anti-inflammatory compounds that could be developed as a functional food ingredient or pharmaceuticals.

13 Mar 2019

Evonik introduces new radiopaque PEEK material for medical implants

Evonik is expanding its product range of biocompatible high-performance polymers of its VESTAKEEP® PEEK brand for medical technology.

From Evonik 13 Mar 2019

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Richard Eglen discusses the use of organoids in drug discovery, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics.

From Corning Life Sciences 13 Mar 2019

Researchers identify potential therapeutic target for blocking early atherosclerosis in progeria

Researchers at the Centro Nacional de Investigaciones Cardiovasculares and the Universidad de Oviedo have discovered a new molecular mechanism involved in the premature development of atherosclerosis in mice with Hutchinson-Gilford progeria syndrome.

12 Mar 2019

Mushroom consumption may reduce odds of having mild cognitive impairment

A team from the Department of Psychological Medicine and Department of Biochemistry at the Yong Loo Lin School of Medicine at the National University of Singapore has found that seniors who consume more than two standard portions of mushrooms weekly may have 50 per cent reduced odds of having mild cognitive impairment.

12 Mar 2019

Study uncovers potential new strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains.

11 Mar 2019

Novel mouse model confirms how “good” and “bad” bacteria affect human acne

Researchers have long believed that Propionibacterium acnes causes acne. But these bacteria are plentiful on everyone's skin and yet not everyone gets acne, or experiences it to the same degree.

8 Mar 2019

Researchers discover facile method for introduction of fluorine atoms into organic molecules

The vast majority of pharmaceuticals employed in the treatment of human diseases are of an organic nature, meaning that the active component is a molecule (or a combination of several molecules) that is constituted of carbon and hydrogen atoms.

6 Mar 2019

Researchers develop method for rapidly measuring proteins' unique vibrations

In the cells of every living organism -- humans, birds, bees, roses and even bacteria -- proteins vibrate with microscopic motions that help them perform vital tasks ranging from cell repair to photosynthesis.

5 Mar 2019

Newly developed bioluminescence sensors pave way for drug discovery

Canadian researchers, working in partnership with Brazilian colleagues, have developed 13 bioluminescence sensors for use in testing the effectiveness of new medical drugs in the laboratory.

2 Mar 2019

Scientists use pulsed infrared light lasers to focus on the action of drugs

Having absolute control of the activity of a molecule in an organism. Deciding when, where and how a drug is activated. These are some of the goals expected to be reached with the so-called photoswitchable molecules, compounds that, in the presence of certain light waves, change their properties.

1 Mar 2019

New strategy may alleviate motor disorders in Parkinson's patients

Scientists of the German Center for Neurodegenerative Diseases and the University Medical Center Goettingen have been able to alleviate motor disorders in mice that resemble those seen in Parkinson's patients.

28 Feb 2019

Researchers find new precise and accurate biomarker of cyanide exposure

Cyanide exposure can happen occupationally or in low levels from inhaling cigarette smoke -- or from being poisoned by someone out to get you.

28 Feb 2019

The Evolution of MDLC in the Pharmaceutical Industry

Dr Kelly Zhang outlines recent advances in multidimensional liquid chromatography (MDLC) for pharmaceutical analysis, to be discussed at Pittcon 2019.

From Pittcon 27 Feb 2019

Big-data analysis finds new link between popular arthritis drug and heart valve calcification

A well-known, four-year study found popular arthritis drug Celebrex no more dangerous for the heart than older drugs in its same classification - commonly called NSAIDs.

23 Feb 2019

Novel MRI sensor can peer deep into the brain to detect intracellular calcium activity

Calcium is a critical signaling molecule for most cells, and it is especially important in neurons. Imaging calcium in brain cells can reveal how neurons communicate with each other; however, current imaging techniques can only penetrate a few millimeters into the brain.

22 Feb 2019

'Holy herb' (Yerba santa) identified as a potential treatment for Alzheimer’s disease

Yerba santa, also known as the ‘Holy Herb’, may have important implications for patients with Alzheimer’s disease.

22 Feb 2019

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Multiple sclerosis is an autoimmune disease that affects more than 2.3 million people worldwide. This debilitating condition periodically shutters communication between the brain and other parts of the body, resulting in symptoms that range from numbness and tingling in the arms and legs to blindness and paralysis.

22 Feb 2019

Johns Hopkins scientists find new compound that may prevent reperfusion injury

In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.

21 Feb 2019

Compound News and Research

Blunting emotional component associated with pain

Avocado seed extract could be potential source for novel anti-inflammatory compounds

Evonik introduces new radiopaque PEEK material for medical implants

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Researchers identify potential therapeutic target for blocking early atherosclerosis in progeria

Mushroom consumption may reduce odds of having mild cognitive impairment

Study uncovers potential new strategy to treat influenza A

Novel mouse model confirms how “good” and “bad” bacteria affect human acne

Researchers discover facile method for introduction of fluorine atoms into organic molecules

Researchers develop method for rapidly measuring proteins' unique vibrations

Newly developed bioluminescence sensors pave way for drug discovery

Scientists use pulsed infrared light lasers to focus on the action of drugs

New strategy may alleviate motor disorders in Parkinson's patients

Researchers find new precise and accurate biomarker of cyanide exposure

The Evolution of MDLC in the Pharmaceutical Industry

Big-data analysis finds new link between popular arthritis drug and heart valve calcification

Novel MRI sensor can peer deep into the brain to detect intracellular calcium activity

'Holy herb' (Yerba santa) identified as a potential treatment for Alzheimer’s disease

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Johns Hopkins scientists find new compound that may prevent reperfusion injury

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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