Respiratory News and Research

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Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Combination of fluvoxamine and inhaled budesonide reduces severe COVID-19 in high-risk outpatients

Research reports the results of a randomized, placebo-controlled trial that investigated the effects of combining fluvoxamine and inhaled budesonide for preventing disease progression in high-risk outpatients with COVID-19. The study found that the combination treatment reduced the incidence of severe disease requiring advanced care.

20 Apr 2023

Observational cohort study of long COVID among 2 million elderly adults

Research estimates the incidence of long COVID and long Flu among Medicare patients using the World Health Organization (WHO) consensus definition. The study compares the incidence, symptomatology, and healthcare utilization between long COVID and long flu patients.

20 Apr 2023

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

In a recent study published in the journal JAMA Network Open, researchers examined the clinical use of dexamethasone for hospitalized patients with coronavirus disease 2019 (COVID-19) respiratory illness and explored the heterogeneity of treatment outcomes across different subgroups.

19 Apr 2023

Can SARS-CoV-2 infection cause diabetes?

This paper reports a population-based cohort study conducted in British Columbia, Canada, which found that SARS-CoV-2 infection is associated with a higher risk of diabetes, particularly among those with severe COVID-19 disease.

19 Apr 2023

Infectious particles of the SARS-CoV-2 virus isolated from hospital air

Quebec scientists have succeeded in isolating infectious particles of the SARS-CoV-2 virus from air samples collected from hospital rooms of COVID-19 patients and kept frozen for more than a year, a new study shows.

19 Apr 2023

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

Announcing a new article publication for Zoonoses journal. Vaccines are among the most effective medical countermeasures against infectious diseases.

19 Apr 2023

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Researchers explored the possible transmission of SARS-CoV-2 to zoo employees from an African lion.

19 Apr 2023

Assessing the efficacy, safety and tolerability of AXA1125 in long COVID patients

Researchers evaluated the effectiveness of endogenous metabolic modulator, AXA1125.

19 Apr 2023

Adapting for endemic not pandemic: Time to reassess universal masking in healthcare

Researchers discuss the changing context of universal masking in healthcare settings amid the COVID-19 pandemic and argue for a dynamic, adaptable approach to infection prevention policies.

19 Apr 2023

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

The newly developed DCFHP-alum COVID-19 vaccine candidate is affordable and effective for mass vaccination.

18 Apr 2023

New biologic inactivates potent opioid and reverses overdose

A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose.

18 Apr 2023

Many top-selling brand-name drugs in Medicare may provide little added therapeutic benefit

Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit.

18 Apr 2023

Ecological and evolutionary implications of the sharing of metabolites between different microbes in the gut microbiome

The researchers provide important insights into the cross-feeding mechanisms of nutrients in the gut microbiome and their impacts on host health.

18 Apr 2023

The impact of SARS-CoV-2 infection in pregnancy on infant growth

Researchers discussed the impact of SARS-CoV-2 infection in pregnancy on infant growth.

18 Apr 2023

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Researchers investigated the tropism of SC2r-CoVs infecting Rhinolophus bats.

18 Apr 2023

Was resuming in-person vs virtual instruction for school students associated with differences in COVID-19 incidence?

Researchers assessed whether in-person education increased coronavirus disease 2019 incidence.

18 Apr 2023

Soaring healthcare costs for RSV-related complications in US seniors 60 plus

In a recent study published in the journal Open Forum Infectious Diseases, researchers explored the correlation between complications caused by a respiratory syncytial virus (RSV) and the associated healthcare costs.

18 Apr 2023

VA and NIH launch new study to better understand chronic symptoms of Gulf War Illness

The Department of Veterans Affairs (VA) and National Institutes of Health have launched a study to gain a better understanding of the chronic symptoms of Gulf War Illness.

17 Apr 2023

A highly efficient platform for detection of SARS-CoV-2 variants

The recent outbreak of the coronavirus disease 2019 (COVID-19) pandemic and the continuous evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have highlighted the significance of new detection methods for global monitoring and prevention.

17 Apr 2023

Respiratory News and Research

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Combination of fluvoxamine and inhaled budesonide reduces severe COVID-19 in high-risk outpatients

Observational cohort study of long COVID among 2 million elderly adults

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

Can SARS-CoV-2 infection cause diabetes?

Infectious particles of the SARS-CoV-2 virus isolated from hospital air

Next-generation vaccine strategies to combat current and emerging SARS-CoV-2 variants

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Assessing the efficacy, safety and tolerability of AXA1125 in long COVID patients

Adapting for endemic not pandemic: Time to reassess universal masking in healthcare

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

New biologic inactivates potent opioid and reverses overdose

Many top-selling brand-name drugs in Medicare may provide little added therapeutic benefit

Ecological and evolutionary implications of the sharing of metabolites between different microbes in the gut microbiome

The impact of SARS-CoV-2 infection in pregnancy on infant growth

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Was resuming in-person vs virtual instruction for school students associated with differences in COVID-19 incidence?

Soaring healthcare costs for RSV-related complications in US seniors 60 plus

VA and NIH launch new study to better understand chronic symptoms of Gulf War Illness

A highly efficient platform for detection of SARS-CoV-2 variants

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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