Therapy News and Research

RSS

Avelumab and cetuximab combination shows promise in phase II skin cancer trial

A phase II clinical trial led by the Alliance for Clinical Trials in Oncology has met its primary endpoint, demonstrating that the combination of avelumab and cetuximab improved progression-free survival (PFS) compared to avelumab alone in patients with advanced cutaneous squamous cell carcinoma (cSCC).

1 Jun 2025

Dual-target CAR T cell therapy shrinks tumors in aggressive brain cancer

A dual-target CAR T cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer.

1 Jun 2025

Combination treatment extends progression-free survival in advanced skin cancer

In patients with an advanced type of skin cancer called cutaneous squamous cell carcinoma (cSCC), those who received the combination of the immunotherapy drug avelumab and targeted agent cetuximab had almost four times longer median progression-free survival compared to patients who received avelumab alone, according to the results of a phase 2 trial presented today at the American Society of Clinical Oncology (ASCO) meeting and concurrently published in the Journal of Clinical Oncology.

1 Jun 2025

Light-powered phagocytic macrophage microrobot combines immune functions with robotic controllability

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells.

31 May 2025

Microfluidic contact lenses emerge as next generation tools for eye care

The tear film coating the eye offers a window into a person's systemic and ocular health, carrying biomarkers such as glucose, electrolytes, and proteins.

31 May 2025

Leading health organizations release guidance on nutrition support for GLP-1 obesity therapies

Four leading organizations in lifestyle medicine, obesity medicine, and nutrition-the American College of Lifestyle Medicine (ACLM), the American Society for Nutrition (ASN), the Obesity Medicine Association (OMA), and The Obesity Society (TOS)-have jointly released a clinical advisory titled "Nutritional Priorities to Support GLP-1 Therapy for Obesity."

31 May 2025

Universal CAR T cell therapy shows promise for aggressive T cell cancers

A new type of immunotherapy that targets aggressive blood cancers shows promising results alongside manageable side effects, according to the results of an international phase 1/2 clinical trial led by researchers at Washington University School of Medicine in St. Louis.

31 May 2025

Triplet therapy significantly improves survival in BRAF V600E-mutated metastatic colorectal cancer

First-line treatment with the triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improved survival compared to the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer, according to new data from the Phase III BREAKWATER trial led by researchers from The University of Texas MD Anderson Cancer Center.

30 May 2025

New trial offers hope for men with aggressive prostate cancer

Many men with aggressive prostate cancer can experience a high rate of recurrence despite treatment.

30 May 2025

New AI test identifies prostate cancer patients who benefit from abiraterone

A new artificial intelligence (AI) test can identify which men with prostate cancer will benefit most from the life-extending drug abiraterone, in clinical trial results presented by scientists from UCL and the Institute of Cancer Research.

30 May 2025

Mass General Brigham researchers share cancer research discoveries at ASCO 2025

Researchers from Mass General Brigham will present research discoveries and outcomes from clinical trials in cancer at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, held May 30-June 3, in Chicago.

30 May 2025

New app can help improve quality of life for caregivers of bone marrow transplant patients

A new study by investigators from Mass General Brigham showed that a new app they created can help improve the quality of life for caregivers of patients undergoing bone marrow transplant (BMT).

30 May 2025

TTF1 identified as key biomarker for advanced KRAS G12C-mutated non-small cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was predictive of survival outcomes for patients with advanced KRAS G12C-mutated non-small cell lung cancer (NSCLC), following treatment with the KRAS targeted therapy sotorasib.

30 May 2025

New insights into decades-old bladder cancer treatment offers clues for immunotherapy

More than three decades ago, the U.S. Food and Drug Administration (FDA) approved Bacillus Calmette-Guérin (BCG) as the first immunotherapy against cancer. And it is still used today to treat early-stage bladder cancer.

29 May 2025

New VR system transforms hand rehabilitation with load free design

In a significant advancement for hand rehabilitation, researchers from Zhengzhou University have introduced a non-hand-worn, load-free VR hand rehabilitation system that could boost therapy development for patients recovering from conditions like stroke and osteoarthritis.

29 May 2025

Early allergen introduction reduces childhood food allergy risk

Investigating allergy prevention, this research highlights early intervention strategies and the promise of biologic treatments in managing allergic conditions.

29 May 2025

Higher BMI, not menopause age, increases hypothyroidism risk

Researchers analyzed over 15,000 postmenopausal Canadian women to investigate whether age at natural menopause influences the risk of developing overt hypothyroidism. The study found no association, but higher BMI was linked to increased hypothyroidism risk.

29 May 2025

Traditional Kava rituals provide alternative pathway to PTSD recovery

Researchers reviewed pilot and qualitative evidence suggesting that combining traditional Pacific kava with talanoa dialogue may help reduce PTSD symptoms among Pacific veterans and first responders. A clinical trial is planned to formally evaluate the safety, efficacy, and cultural adaptability of this innovative, culturally grounded therapy.

29 May 2025

Study expands smoking cessation and lung cancer screening to North Queensland

Cairns and Townsville residents who want to give up smoking can access free nicotine replacement therapies and potentially life-saving lung cancer screening by participating in a research study.

29 May 2025

New four drug combination sets new standard in myeloma care

A new four-drug combination is highly effective and safe in patients with newly diagnosed multiple myeloma, according to data presented at the annual meeting of the American Society of Clinical Oncology, held May 30 through June 3 in Chicago.

29 May 2025