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Revolution by Evolution: Protein Science and its Impact on Drug Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Mark Abbott, the Managing Director of Peak Proteins, about protein science and its significance in drug discovery.

10 Nov 2023

Who will care for older adults? We’ve plenty of know-how but too few specialists

Thirty-five years ago, Jerry Gurwitz was among the first physicians in the United States to be credentialed as a geriatrician — a doctor who specializes in the care of older adults.

10 Nov 2023

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

In this groundbreaking study, researchers developed a mucosal adenoviral-vector vaccine, ChAd-SARS-CoV-2-S, which demonstrated sustained and robust immunity against a challenging Omicron variant in nonhuman primates, indicating a promising direction for durable COVID-19 protection strategies. Unlike traditional intramuscular vaccines, this mucosal vaccine elicited a comprehensive immune response, potentially paving the way for more effective and long-lasting COVID-19 vaccines.

9 Nov 2023

Pediatric viral threats surge in the 21st century: A call for One Health approach

Scoping review in "Pediatric Research" examines the rise of pediatric viral diseases in the 21st century and underscores the importance of a One Health approach, integrating human, animal, and ecosystem health, to combat these emerging and re-emerging infectious threats effectively.

9 Nov 2023

Allergies linked to heightened risk of long COVID, new review suggests

Systematic review indicates that pre-existing allergic conditions like asthma and allergic rhinitis may be linked to an increased risk of developing long COVID. Despite some evidence, the certainty remains low due to potential biases and confounding factors, highlighting the need for more rigorous research to determine the impact of these allergies on prolonged COVID-19 symptoms.

9 Nov 2023

WHO experts update guidance on COVID-19 treatments

A panel of international experts representing the World Health Organization's Guideline Development Group has updated its guidance on treatments for patients with covid-19.

9 Nov 2023

HMS immunologist unravels the mysteries of how the immune system communicates

The immune system is a crucial part of our survival, regularly fending off wide-ranging attacks on the body, both internal and external.

9 Nov 2023

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

The work of the COVID Moonshot Consortium is being published in the prestigious journal Science on 10 November, revealing their discovery of a potent SARS-CoV-2 antiviral lead compound.

9 Nov 2023

ICMRA celebrates 10 years of global cooperation in regulating medicinal products

This year marks ten years since the MHRA joined seven other global regulators to establish ICMRA to address the need for strong global cooperation and alignment in the regulation of medicinal products.

9 Nov 2023

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

The International Vaccine Institute (IVI), an international organization with a mission to discover, develop, and deliver safe, effective, and affordable vaccines for global health, and Bio Farma, a biotechnology company based in West Java, Indonesia, announced today that Bio Farma's Bio-TCV typhoid conjugate vaccine (TCV) was licensed in Indonesia following marketing approval from Badan Pengawas Obat dan Makanan (BPOM), the national regulatory authority.

9 Nov 2023

A new RSV shot could help protect babies this winter — if they can get it in time

Emily Bendt was in her third trimester of pregnancy when she first heard the Centers for Disease Control and Prevention had approved a new shot for infants to protect them from the respiratory syncytial virus, or RSV.

9 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Study compares the immunogenicity and safety of two SARS-CoV-2 vaccines

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019. Since then, extensive efforts have been made to develop and evaluate vaccines to combat the virus.

8 Nov 2023

Allergic conditions linked to higher risk of Long-COVID, study finds

In an analysis of published prospective studies of people of all ages with confirmed SARS-CoV-2 infection who were followed for at least 12 months, pre-existing allergic conditions were linked to higher risks of experiencing long-term symptoms associated with COVID-19, or Long-COVID.

8 Nov 2023

New antifungal molecule shows promise in combatting fungal infections without toxicity

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

8 Nov 2023

Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder?

Researchers assessed the efficacy and compared the relative effectiveness of various pharmacological treatments for alcohol use disorder.

8 Nov 2023

US to cover HIV prevention drugs for older Americans to stem spread of the virus

A proposed federal policy aims to protect older Americans from contracting HIV by offering free preventive medication, the latest effort to catch up to much of Europe and Africa in stemming the spread of the virus.

8 Nov 2023

Personal biases warp COVID-19 memories, posing a challenge for future pandemic policies

In a series of studies, researchers found that personal biases significantly influence how individuals remember the COVID-19 pandemic, which could potentially shape historical narratives and impact future pandemic policies. They suggest that recognizing these biases is crucial for developing long-term strategies that maintain societal trust and cohesion.

7 Nov 2023

Immune imprinting: The crux of waning COVID-19 booster effectiveness against new variants

The study in Nature Microbiology reviews the concept of immune imprinting and its influence on antibody responses to SARS-CoV-2, highlighting challenges for COVID-19 booster vaccination efficacy against emerging variants. Researchers suggest that understanding immune imprinting is crucial for developing vaccines that elicit broad and lasting immune protection.

7 Nov 2023

Pandemic isolation linked to cognitive decline in UK's older population, study finds

The Lancet study on UK older adults finds COVID-19 pandemic's social restrictions contributed to a marked decline in cognitive functions like working memory and executive function, with sustained effects into the second year despite eased restrictions.

7 Nov 2023

covid 19 News and Research

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

Who will care for older adults? We’ve plenty of know-how but too few specialists

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

Pediatric viral threats surge in the 21st century: A call for One Health approach

Allergies linked to heightened risk of long COVID, new review suggests

WHO experts update guidance on COVID-19 treatments

HMS immunologist unravels the mysteries of how the immune system communicates

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

ICMRA celebrates 10 years of global cooperation in regulating medicinal products

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

A new RSV shot could help protect babies this winter — if they can get it in time

Cannabis use alters DNA methylation, with implications beyond smoking effects

Study compares the immunogenicity and safety of two SARS-CoV-2 vaccines

Allergic conditions linked to higher risk of Long-COVID, study finds

New antifungal molecule shows promise in combatting fungal infections without toxicity

Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder?

US to cover HIV prevention drugs for older Americans to stem spread of the virus

Personal biases warp COVID-19 memories, posing a challenge for future pandemic policies

Immune imprinting: The crux of waning COVID-19 booster effectiveness against new variants

Pandemic isolation linked to cognitive decline in UK's older population, study finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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