in vivo News and Research

RSS

Revolutionary SPion technology enables remote analysis with mass spectrometry

Trace Matters Scientific today introduced SPion -a revolutionary technology that enables the world's most sensitive and versatile remote analysis with mass spectrometry.

16 Feb 2020

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Scientists from Far Eastern Federal University, University of Geneva (Switzerland), Minjiang University, and Fuzhou University (China) pointed out WDR74 protein playing an important role in lung cancer and melanoma primary tumors/metastases progression.

16 Feb 2020

Novel melatonin receptor molecules potentially address circadian rhythm disturbances

Like breathing or blinking, behaviors regulated by our circadian rhythms, such as digestion and sleep-wake cycles, go unnoticed by most people.

10 Feb 2020

New method to treat cancer with iron oxide nanoparticles

The concept is based on the interaction of resonant semiconductor iron oxide Fe2O3 nanoparticles with light. Particles previously loaded with the antitumor drug are injected in vivo and further accumulate at the tumor areas.

10 Feb 2020

Novel innate immunity factor inhibits HIV infection by targeting lipid rafts, study finds

The human protein apolipoprotein A-I binding protein inhibits HIV replication by targeting lipid rafts and reducing virus-cell fusion, according to a new study published in the premier American Society for Microbiology journal mBio by researchers from the George Washington University.

10 Feb 2020

New handheld 3D skin printer accelerates healing of large burn wounds

A new handheld 3D printer can deposit sheets of skin to cover large burn wounds - and its "bio-ink" can accelerate the healing process.

4 Feb 2020

Scientists describe genetic program behind primordial lung progenitors

For the first time, researchers describe the genetic program behind primordial lung progenitors--embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth.

31 Jan 2020

New combination treatment could help fight advanced melanoma

A study by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that using an immunotherapy drug called NKTR-214, also known as bempegaldesleukin, in combination with an infusion of anti-tumor immune cells, or T cells, may produce a stronger immune response that could help fight advanced melanoma.

31 Jan 2020

Researchers provide first insight into innovative approach for diabetes care

The circadian clock system (from Latin "circa diem", about a day) allows the organisms to anticipate periodical changes of geophysical time, and to adjust to these changes. Nearly all the cells in our body comprise molecular clocks that regulate and synchronize metabolic functions to a 24-hour cycle of day-night changes.

31 Jan 2020

Researchers identify potential target in the fight against MERS

First identified in 2012, the MERS-coronavirus is capable of causing severe and often fatal pneumonia. There are no effective treatments for MERS.

29 Jan 2020

New strategy using organoids to study childhood brain tumors

A new study reports the creation of in vitro models of brain tumors in children using organoids derived from stem cells, which will help to screen new drugs for efficacy and thus improve the rate of drug development. The study, titled 'Modeling medulloblastoma in vivo and with human cerebellar organoids,' is published in the journal Nature Communications.

29 Jan 2020

New way to treat stroke using an already FDA-approved drug shows promise

Stroke is the third leading cause of death and disability in the United States. More than 87 percent are ischemic strokes, caused by obstruction of one or more cerebral arteries. With limited progress in developing treatments, there is a critical need for neuroprotective agents to effectively treat stroke.

29 Jan 2020

New blood sugar tool could one day replace uncomfortable finger-prick test

Researchers have developed a new way to monitor blood sugar levels that could replace the needle-prick method that people with diabetes currently use.

29 Jan 2020

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

29 Jan 2020

Avacta demonstrates initial proof-of-concept for TMAC drug conjugates in pre-clinical study

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that it has demonstrated initial proof-of-concept for its proprietary new class of drug conjugate, TMAC, in a pre-clinical animal model of cancer.

From Avacta Life Sciences Ltd. 28 Jan 2020

Do biologists and physicists approach AFM differently?

This was the question at the forefront of my mind as I attended the Linz Winter Workshop back in February. Do biologists and physicists approach AFM differently and, does it matter?

From Nu Nano Ltd 28 Jan 2020

Improving drug testing with comprehensive 'Organ Chip' platform

The U.S. Food and Drug Administration approves only 13.8% of all tested drugs, and these numbers are even lower in "orphan" diseases that affect relatively few people.

27 Jan 2020

Biodegradable bridge for nerve injuries

Researchers have successfully tried a biodegradable bridge like device (biodegradable polycaprolactone PCL conduit) in vivo for management of nerve injuries. The team published their findings in a paper titled, “Long-gap peripheral nerve repair through sustained release of a neurotrophic factor in nonhuman primates,” in the latest issue of the journal Science Translational Medicine.

26 Jan 2020

Stanford scientists complete first global census of cell surface proteins

Stanford scientists have completed the first global census of diverse proteins sprouting tree-like from the outer membrane of a cell. These cell surface proteins govern how cells interact with one another and how they assemble into tissues and organs such as hearts and brains.

24 Jan 2020

Scientists visualize diabetes-related proteins at high resolution

Scientists have examined a key receptor for the first time at high resolution - broadening understanding of how it might function, and opening the door to future improvements in treating conditions such as type 2 diabetes.

24 Jan 2020