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New theory for how stem cells decide whether to become liver or pancreatic cells

Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell's fate, the researchers found, is determined by the nearby presence of prostaglandin E2, a messenger molecule best known for its role in inflammation and pain.

14 Feb 2014

New approach for treating leukemia

A group of researchers at the Institute for Research in Immunology and Cancer (IRIC) of Université de Montréal discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression.

14 Feb 2014

FDA-approved drug pregabalin effectively treats RLS symptoms with less side effects

A report in the Feb. 13 New England Journal of Medicine confirms previous studies suggesting that long-term treatment with the type of drugs commonly prescribed to treat restless leg syndrome (RLS) can cause a serious worsening of the condition in some patients.

14 Feb 2014

Longer looks: Women's advantages in health law; health effects of the 'American Dream'

Every week reporter Ankita Rao selects interesting reading from around the Web.

14 Feb 2014

Scientists identify network of genes that controls human brain activity, memory and schizophrenia

Many psychiatric disorders are accompanied by memory deficits. Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia.

14 Feb 2014

Intravenous magnesium fails to improve stroke-related disability

Giving intravenous magnesium to stroke patients soon after the start of symptoms, in an attempt to protect brain cells deprived of oxygen, failed to improve stroke-related disability 3 months later, according to research presented at the American Stroke Association's International Stroke Conference 2014

13 Feb 2014

Researchers discover promising new approach for leukemia treatment

A group of researchers at the Institute for Research in Immunology and Cancer of Universit- de Montr-al discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression. That gene, known as Brg1 is a key regulator of leukemia stem cells that are the root cause of the disease, resistance to treatment and relapse.

13 Feb 2014

Aerpio Therapeutics doses first patient in AKB-9778 Phase 2 trial for diabetic macular edema treatment

Aerpio Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on advancing innovative therapies for vascular diseases, today announced that it has dosed the first patient in a Phase 2 trial evaluating AKB-9778, a Tie2 activator, alone and in combination with ranibizumab (Lucentis) for the treatment of diabetic macular edema (DME). AKB-9778 is a first-in-class inhibitor of human protein tyrosine phosphatase beta (HPTPβ) that activates the Tie2 pathway to promote vascular stability, preventing abnormal blood vessel growth and vascular leak.

13 Feb 2014

Quintiles' growth in service revenues increases 7.7% in Q4 2013

Quintiles Transnational Holdings Inc. today reported its financial results for the fourth quarter ended December 31, 2013.

13 Feb 2014

FDA grants full approval of SYNRIBO for injection

Teva Pharmaceutical Industries Ltd. today announced that the U.S. Food and Drug Administration has granted full approval of SYNRIBO (omacetaxine mepesuccinate) for injection. This oncology portfolio product received an accelerated approval in October, 2012 with additional clinical trial data required to fulfill post marketing requirements set forth by the FDA.

13 Feb 2014

Clot-busting tPA therapy for ischemic stroke patients can avoid lengthy, restrictive monitoring in ICU

A Johns Hopkins study of patients with ischemic stroke suggests that many of those who receive prompt hospital treatment with "clot-busting" tissue plasminogen activator (tPA) therapy can avoid lengthy, restrictive monitoring in an intensive care unit (ICU).

13 Feb 2014

Study reveals that more than 14% of pregnant women are prescribed opioids for pain

More than 14 percent of pregnant women were prescribed opioids (narcotics) for pain at some time during their pregnancy, according to a study posted to the online version of Anesthesiology.

13 Feb 2014

Jersey Shore University wins AMA Grant to educate youth about prescription medication safety

Jersey Shore University Medical Center was recently awarded an American Medical Association (AMA) Foundation Healthy Living Grant to educate youth about prescription medication safety.

13 Feb 2014

CHOP develops unique laboratory test to characterize genes that encode HLA molecules

Immunogenetics experts at The Children's Hospital of Philadelphia (CHOP) have developed a unique laboratory test to characterize the genes that encode HLA molecules. The test relies on faster, more comprehensive gene sequencing technology to type human leukocyte antigens (HLAs)--complex, highly variable proteins on cell surfaces that are essential to immune function.

13 Feb 2014

Alvogen launches Inflectra into Central and Eastern Europe

Alvogen, the multinational pharmaceuticals company, today announced the launch of Inflectra (Infliximab) into Central and Eastern Europe. Inflectra, Europe's first biosimilar monoclonal antibody (mAb) therapy that has been approved for the treatment of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis, Crohn's disease (CD), ulcerative colitis (UC), psoriatic arthritis (PsA) and psoriasis.

13 Feb 2014

Drive for novel antibiotics against gram-negative bacteria

Over 30 European universities, research institutes, and companies, led by GlaxoSmithKline and Uppsala University, are joining forces in a 6 year programme supported by the Innovative Medicines Initiative (IMI) to develop novel antibiotics against Gram-negative pathogens.

13 Feb 2014

Researchers identify effective target for human autoimmune disease

Researchers at King's College London have identified a new gene (PIM1), which could be an effective target for innovative treatments and therapies for the human autoimmune disease, psoriasis.

13 Feb 2014

FDA approves InControl Medical's InToneMV device for treatment of female urinary incontinence

InControl Medical, LLC, a women's health company focusing on female urinary incontinence, has received FDA clearance for their proprietary, patented, InToneMV, providing women who suffer with vaginal atrophy a smaller, more comfortable medical device for the treatment of stress, urge and mixed female urinary incontinence without surgery or drugs.

12 Feb 2014

Scientists explain why women with dense breast tissue at greater risk of developing breast cancer

Scientists from The University of Manchester working with IBM Research have identified a key biological mechanism that for the first time explains why women with dense breast tissue are at greater risk of developing breast cancer.

12 Feb 2014

Horizon Discovery, Haplogen sign worldwide distribution agreement

Horizon Discovery, a leading provider of research tools to support translational genomics and the development of personalized medicines, today announced it has signed a worldwide distribution agreement with Haplogen GmbH, with immediate effect.

12 Feb 2014

Drugs News and Research

New theory for how stem cells decide whether to become liver or pancreatic cells

New approach for treating leukemia

FDA-approved drug pregabalin effectively treats RLS symptoms with less side effects

Longer looks: Women's advantages in health law; health effects of the 'American Dream'

Scientists identify network of genes that controls human brain activity, memory and schizophrenia

Intravenous magnesium fails to improve stroke-related disability

Researchers discover promising new approach for leukemia treatment

Aerpio Therapeutics doses first patient in AKB-9778 Phase 2 trial for diabetic macular edema treatment

Quintiles' growth in service revenues increases 7.7% in Q4 2013

FDA grants full approval of SYNRIBO for injection

Clot-busting tPA therapy for ischemic stroke patients can avoid lengthy, restrictive monitoring in ICU

Study reveals that more than 14% of pregnant women are prescribed opioids for pain

Jersey Shore University wins AMA Grant to educate youth about prescription medication safety

CHOP develops unique laboratory test to characterize genes that encode HLA molecules

Alvogen launches Inflectra into Central and Eastern Europe

Drive for novel antibiotics against gram-negative bacteria

Researchers identify effective target for human autoimmune disease

FDA approves InControl Medical's InToneMV device for treatment of female urinary incontinence

Scientists explain why women with dense breast tissue at greater risk of developing breast cancer

Horizon Discovery, Haplogen sign worldwide distribution agreement

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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