Protein C News and Research

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Researchers gain better understanding of HIV infection through electron microscopy

The human intestinal tract, or gut, is best known for its role in digestion. But this collection of organs also plays a prominent role in the immune system. In fact, it is one of the first parts of the body that is attacked in the early stages of an HIV infection. Knowing how the virus infects cells and accumulates in this area is critical to developing new therapies for the over 33 million people worldwide living with HIV. Researchers at the California Institute of Technology are the first to have utilized high-resolution electron microscopy to look at HIV infection within the actual tissue of an infected organism, providing perhaps the most detailed characterization yet of HIV infection in the gut.

30 Jan 2014

Alexion Pharmaceuticals reports full year 2013 GAAP and non-GAAP financial results

Alexion Pharmaceuticals, Inc. today announced financial results for the quarter and year ended December 31, 2013. For the three months ended December 31, 2013, Alexion Pharmaceuticals, Inc. ("Alexion" or the "Company") reported net product sales of Soliris® (eculizumab) of $441.9 million, compared to $320.5 million for the same period in 2012.

30 Jan 2014

TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified new potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease.

30 Jan 2014

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions.

30 Jan 2014

Exposure to DDT may increase likelihood of developing Alzheimer's disease later in life

Exposure to DDT may increase the likelihood of developing Alzheimer's disease later in life, a study with researchers at UT Southwestern Medical Center suggests. While previous studies have linked chronic diseases such as cancer and diabetes to DDT, this is the first clinical study to link the U.S.-banned pesticide to Alzheimer's disease.

30 Jan 2014

Bladder, lung cancers are marked by shared differences in genetics that control cell cycle

A University of Colorado Cancer Center study published in the journal PLoS ONE shows that bladder and lung cancers are marked by shared differences in the genetics that control the cell cycle.

30 Jan 2014

Research shows promise for developing a method of clearly identifying cancerous tissue during surgery

First-of-its-kind research by the Innovation Institute at Henry Ford Hospital shows promise for developing a method of clearly identifying cancerous tissue during surgery on one of the most common and deadliest types of brain tumor.

30 Jan 2014

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

Johns Hopkins researchers have discovered that valproic acid, a widely prescribed drug for treating epilepsy, has the additional benefits of reducing fat accumulation in the liver and lowering blood sugar levels in the blood of obese mice.

30 Jan 2014

Study details about healthful compounds contained in hempseed

Long stigmatized because of its "high"-inducing cousins, hemp - derived from low-hallucinogenic varieties of cannabis - is making a comeback, not just as a source of fiber for textiles, but also as a crop packed with oils that have potential health benefits.

30 Jan 2014

UNC researchers develop new radiation-free ultrasound technique to detect, monitor cancer

While ultrasound provides a less expensive and radiation-free alternative to detecting and monitoring cancer compared to technologies such as X-rays, CT scans, and MRIs, ultrasound has seen limited use in cancer treatment due to clarity and resolution issues.

29 Jan 2014

Researchers identify new subgroup of patients suffering from schizophrenia with motor disorders

Researchers led by Marta Barrachina, Institute of Neuropathology of the Bellvitge Biomedical Research Institute (IDIBELL) have identified a new subgroup of patients suffering from schizophrenia characterized by motor disorders.

29 Jan 2014

Researchers design semi-synthetic proteins to analyse body's vital signal processes

Proteins play a fundamental role in almost all biological processes. They consist of chains constructed of up to 20 different amino acids, and their composition, structure and function are controlled by the genetic code.

29 Jan 2014

Scientists develop monoclonal antibodies that may lead to new, innovative treatments for cancer patients

Using monoclonal antibodies to fight cancer is a complex, yet promising area of study. At Memorial Sloan Kettering Cancer Center, physician-scientists have focused their attention on expanding the current therapeutic antibody repertoire, and believe a newly developed platform will do just that - ultimately leading to new and innovative treatments for cancer patients with a broad range of malignancies.

29 Jan 2014

AMSilk completes preclinical testing of proprietary silicone breast implant coating

AMSilk has completed preclinical testing of its proprietary silicone implant coating made from spider silk. AMSilk's coating consists of a thin layer of spider silk proteins manufactured by AMSilk.

29 Jan 2014

Biologists identify protein targets for next-generation of anti-HIV drugs

People infected with the Human Immunodeficiency Virus (HIV) can stave off the symptoms of AIDS thanks to drug cocktails that mainly target three enzymes produced by the virus, but resistant strains pop up periodically that threaten to thwart these drug combos.

29 Jan 2014

Study: Genetic mutations in titin gene can cause skeletal muscle disease

A University of Arizona doctoral candidate has shown for the first time that genetic mutations in the titin gene can cause skeletal muscle myopathy, a disease in which muscle fibers do not function properly, resulting in muscle weakness.

29 Jan 2014

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

In recent years, mutations in two metabolic enzymes, isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2), have been identified in approximately 20 percent of all acute myeloid leukemias (AML). As a result, mutant IDH proteins have been proposed as attractive drug targets for this common form of adult leukemia.

29 Jan 2014

Researchers create vaginal cream using silver nanoparticles to control transmition of HIV

The product has proven efficiency in lab tests, although clinical trials are yet to be performed. After discovering that silver nanoparticles are capable of blocking the entry of Human Immunodeficiency Virus (HIV) into the organism, a group of researchers from the University of Texas, in collaboration with Humberto Lara Villegas, specialist in nanoparticles and virology from the University of Monterrey, Mexico (UDEM), create a vaginal cream to control the transmition of the virus.

28 Jan 2014

New halal testing method for detecting pig and horse contamination of meat

The mislabeling of meat products sold for human consumption has serious implications from a safety and ethical perspective. With recent news stories of pork and horsemeat contamination in different parts of the world, a renewed need for specialized testing of the food supply has rapidly arisen.

28 Jan 2014

Researchers discover protein required for growth of hair-like structures on cell surfaces

A team of researchers from Penn State University and the University of California has discovered a protein that is required for the growth of tiny, but critical, hair-like structures called cilia on cell surfaces.

28 Jan 2014

Protein C News and Research

Researchers gain better understanding of HIV infection through electron microscopy

Alexion Pharmaceuticals reports full year 2013 GAAP and non-GAAP financial results

TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

Exposure to DDT may increase likelihood of developing Alzheimer's disease later in life

Bladder, lung cancers are marked by shared differences in genetics that control cell cycle

Research shows promise for developing a method of clearly identifying cancerous tissue during surgery

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

Study details about healthful compounds contained in hempseed

UNC researchers develop new radiation-free ultrasound technique to detect, monitor cancer

Researchers identify new subgroup of patients suffering from schizophrenia with motor disorders

Researchers design semi-synthetic proteins to analyse body's vital signal processes

Scientists develop monoclonal antibodies that may lead to new, innovative treatments for cancer patients

AMSilk completes preclinical testing of proprietary silicone breast implant coating

Biologists identify protein targets for next-generation of anti-HIV drugs

Study: Genetic mutations in titin gene can cause skeletal muscle disease

Transgenic mouse model validates mutant IDH2 protein as candidate for targeted anticancer therapies

Researchers create vaginal cream using silver nanoparticles to control transmition of HIV

New halal testing method for detecting pig and horse contamination of meat

Researchers discover protein required for growth of hair-like structures on cell surfaces

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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