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Researchers develop and validate polygenic risk scores for six common diseases

A person's risk of developing diseases such as type 2 diabetes or breast cancer may be influenced by thousands of genetic differences.

18 Apr 2022

Insight into the future of genetic testing

In this interview, we speak to Sheetal Parmar, vice president of medical affairs and head of clinical services at Natera, about their cell-free DNA (cfDNA) testing services.

From Natera 15 Apr 2022

New short-course treatment effective against HIV-associated cryptococcal meningitis

A new short-course treatment is effective against HIV-associated cryptococcal meningitis with fewer serious side effects, and has the potential to reduce the length and cost of hospital admissions, a study shows.

15 Apr 2022

About one in four adults has a liver condition that is a risk factor for heart disease

It is estimated that about one in four adults worldwide has a liver condition that is a risk factor for heart disease, according to a new American Heart Association scientific statement published today in the Association's peer-reviewed journal Arteriosclerosis, Thrombosis, and Vascular Biology.

14 Apr 2022

Gut microbes play a key role in regulating pancreas function, size and hormone secretion

Gut microbes can regulate the exocrine and endocrine functions of the pancreas and hormone production of the gastrointestinal tract, findings that may help develop potential treatments for diabetes and other diseases, a team of researchers from Boston College, Joslin Diabetes Center, and Maastricht University, Netherlands, report in the journal Diabetes.

13 Apr 2022

Low-dose lithium attenuates kidney aging in mice

Best known therapeutically as a treatment for bipolar disorder, lithium has long intrigued researchers with its potential age-defying properties.

12 Apr 2022

Research using kidney organoids may lead to new targets to help prevent or treat CKD

To a certain extent, kidneys have the capacity to repair themselves after being injured, but a switch can occur from such intrinsic repair to incomplete repair that leads to irreversible damage and chronic kidney disease (CKD).

12 Apr 2022

Dog owners' feeding habits and the impact of FDA hygiene protocols on dog food dish contamination

A survey has recently been conducted by the North Carolina State University, USA, to evaluate the pet food and dish handling habits of pet owners and their impact on bacterial contamination.

12 Apr 2022

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

A recent study illustrated the enhanced distinct clustering of pseudotyped particles (PPs) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

12 Apr 2022

Novel strategy can shrink tumors and prolong survival in mice

A research team based at the University of Ottawa and The Ottawa Hospital has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attack.

11 Apr 2022

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Researchers identified an ultralong bovine antibody that neutralizes SARS-CoV-2 and SARS-CoV.

11 Apr 2022

Study explores phytochemical-based antivirals against SARS-CoV-2 infection

A new study depicted plant-based biologically active antiviral agents that are effective against SARS-CoV-2 infection.

11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

Cancer risk and related mortality significantly higher among patients with kidney disease

Patients with kidney disease may have an increased risk of cancer and may be more likely to die from cancer.

8 Apr 2022

City of Hope's late-breaking clinical trial data to be presented at AACR

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present late-breaking and clinical trial findings at this year's American Association for Cancer Research Annual Meeting, which begins today.

8 Apr 2022

SARS-CoV-2 Delta-Omicron recombinant identified in a transplant patient treated with Sotrovimab

Researchers described a case of co-infection with SARS-CoV-2 variants of concern, Delta and Omicron.

8 Apr 2022

Scientists are searching for the ‘perfect protein’ to develop mRNA-based malaria vaccine

After the success of mRNA vaccines against COVID-19, scientists are cautiously optimistic that the same technology can be used to tackle other widespread diseases such as malaria.

7 Apr 2022

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Nearly half of heart disease patients have insomnia, according to research presented at ESC Preventive Cardiology 2022, a scientific congress of the European Society of Cardiology, and published in SLEEP Advances.

7 Apr 2022

Patient outcomes after influenza, RSV, or SARS-CoV-2 hospitalization

A recent study posted to the medRxiv* preprint server investigated the elements that predicted all-cause mortality among individuals hospitalized due to influenza, respiratory syncytial virus (RSV), or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

7 Apr 2022

Severe COVID linked to RAAS and hyperlipidemia associated metabolic syndrome conditions

A recent study posted to the medRxiv* preprint server investigated the association of renin-angiotensin-aldosterone system (RAAS)-mediated hypertension (HT) with coronavirus disease 2019 (COVID-19).

6 Apr 2022

Kidney News and Research

Researchers develop and validate polygenic risk scores for six common diseases

Insight into the future of genetic testing

New short-course treatment effective against HIV-associated cryptococcal meningitis

About one in four adults has a liver condition that is a risk factor for heart disease

Gut microbes play a key role in regulating pancreas function, size and hormone secretion

Low-dose lithium attenuates kidney aging in mice

Research using kidney organoids may lead to new targets to help prevent or treat CKD

Dog owners' feeding habits and the impact of FDA hygiene protocols on dog food dish contamination

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

Novel strategy can shrink tumors and prolong survival in mice

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Study explores phytochemical-based antivirals against SARS-CoV-2 infection

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

Cancer risk and related mortality significantly higher among patients with kidney disease

City of Hope's late-breaking clinical trial data to be presented at AACR

SARS-CoV-2 Delta-Omicron recombinant identified in a transplant patient treated with Sotrovimab

Scientists are searching for the ‘perfect protein’ to develop mRNA-based malaria vaccine

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Patient outcomes after influenza, RSV, or SARS-CoV-2 hospitalization

Severe COVID linked to RAAS and hyperlipidemia associated metabolic syndrome conditions

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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