Pharmaceuticals News and Research

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Infantile spasms and multiple sclerosis relapse data presented at AAN

Mallinckrodt plc, a specialty pharmaceutical company, announced new results from two company-sponsored studies: one study on use of H.P. Acthar® Gel (repository corticotropin injection) in patients with infantile spasms (IS) and a second study on the economic burden of moderate-to-severe multiple sclerosis (MS) relapse.

2 May 2017

New chiral molecular sieves may lead to production of better drugs

An international team of researchers, led by Mark E. Davis at Caltech, has succeeded in making the first chiral molecular sieves. This discovery opens new areas of investigation in both chemistry and biology, and has broad implications for pharmaceutical companies and other specialized chemical manufacturers.

2 May 2017

Survey: One in three American adults could have experienced sign of warning stroke

About one in three American adults experienced a symptom consistent with a warning or "mini" stroke, but almost none - 3 percent - took the recommended action, according to a new survey from the American Heart Association/American Stroke Association.

2 May 2017

Takeda announces accelerated approval from FDA for new lung cancer treatment

Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that ALUNBRIG (brigatinib) has received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.

28 Apr 2017

FDA approves new drug and chemotherapy combination for treatment of adult patients with AML

The U.S. Food and Drug Administration today approved Rydapt (midostaurin) for the treatment of adult patients with newly diagnosed acute myeloid leukemia who have a specific genetic mutation called FLT3, in combination with chemotherapy.

28 Apr 2017

Cheaper topical steroids could lead to potential health care and out-of-pocket savings

Although topical steroids are among the most commonly prescribed medications by dermatologists, there are limited data on spending and use for this class of drugs.

28 Apr 2017

Experts defy exclusion of acupuncture in two British governmental guidelines

Even as news in the United States recently highlighted the growing inclusion of acupuncture and other complementary and integrative medicine therapies in guidelines for multiple pain conditions, the exclusion of acupuncture in two British governmental guidelines is challenged in a paper and a commentary that are presently available free on The Journal of Alternative and Complementary Medicine website until May 29, 2017.

28 Apr 2017

Stivarga receives expanded FDA approval for treatment of liver cancer

The U.S. Food and Drug Administration today expanded the approved use of Stivarga (regorafinib) to include treatment of patients with hepatocellular carcinoma (HCC or liver cancer) who have been previously treated with the drug sorafenib.

28 Apr 2017

FDA approves first drug for treating rare form of Batten disease

The U.S. Food and Drug Administration today approved Brineura (cerliponase alfa) as a treatment for a specific form of Batten disease. Brineura is the first FDA-approved treatment to slow loss of walking ability in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase-1 (TPP1) deficiency.

27 Apr 2017

Nose2Brain project aims to develop better therapy for multiple sclerosis

Medically active substances are normally distributed via the blood - either directly by injection into the bloodstream or indirectly, for example through the digestive tract after oral administration.

27 Apr 2017

Antidepressant improves drug delivery across the blood-brain barrier, rat study shows

NIH rat study suggests amitriptyline temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain.

27 Apr 2017

Scientists announce ‘outstanding’ results of new blood cancer study

Scientists have described new results of a blood cancer study as 'outstanding' in tackling previously untreatable forms of chronic lymphocytic leukemia.

27 Apr 2017

METTLER TOLEDO’s weighing and dosing solutions enable contract R&D lab to meet customers’ requirements

As pharmaceutical companies are held to increasingly aggressive product innovation targets, they rely on contracted partners to help with process innovation in drug formulation and manufacturing.

From Mettler-Toledo International Inc. 27 Apr 2017

Early blood test can predict vaccine immunogenicity

Within seven days of vaccination, a blood test early after vaccination can predict whether vaccines based on living, modified viruses have had the desired effect.

26 Apr 2017

Exposure to variable temperatures may have positive effect on health

Exposure to environments outside a comfortable temperature could help tackle major metabolic diseases, such as diabetes and obesity, and should be reflected in modern building practices, finds a study published today.

26 Apr 2017

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.

26 Apr 2017

Brown University researchers develop new multi-reaction catalyst

Brown University researchers have developed a new composite catalyst that can perform four separate chemical reactions in sequential order and in one container to produce compounds useful in making a wide range of pharmaceutical products.

25 Apr 2017

Orange essential oil may offer non-pharmaceutical option to help improve PTSD

About 8 percent of people will develop post-traumatic stress disorder at some point in their lives, according to the U.S. Department of Veterans Affairs, yet treatments for this debilitating condition remain limited.

25 Apr 2017

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

Researchers at UConn Health used stem cells derived from patients with Angelman syndrome to identify the underlying cellular defects that cause the rare neurogenetic disorder, an important step in the ongoing search for potential treatments for Angelman and a possible cure.

25 Apr 2017

New report suggests innovative approaches for better response to chemical inhalation disasters

Better medical responses to the accidental or intentional release of inhaled toxic chemicals are being developed, but the field faces considerable challenges, according to a new report by an international panel of experts.

21 Apr 2017

Pharmaceuticals News and Research

Infantile spasms and multiple sclerosis relapse data presented at AAN

New chiral molecular sieves may lead to production of better drugs

Survey: One in three American adults could have experienced sign of warning stroke

Takeda announces accelerated approval from FDA for new lung cancer treatment

FDA approves new drug and chemotherapy combination for treatment of adult patients with AML

Cheaper topical steroids could lead to potential health care and out-of-pocket savings

Experts defy exclusion of acupuncture in two British governmental guidelines

Stivarga receives expanded FDA approval for treatment of liver cancer

FDA approves first drug for treating rare form of Batten disease

Nose2Brain project aims to develop better therapy for multiple sclerosis

Antidepressant improves drug delivery across the blood-brain barrier, rat study shows

Scientists announce ‘outstanding’ results of new blood cancer study

METTLER TOLEDO’s weighing and dosing solutions enable contract R&D lab to meet customers’ requirements

Early blood test can predict vaccine immunogenicity

Exposure to variable temperatures may have positive effect on health

Study reveals promising results for primary liver cancer patients treated with SIR-Spheres Y-90 resin microspheres

Brown University researchers develop new multi-reaction catalyst

Orange essential oil may offer non-pharmaceutical option to help improve PTSD

Scientists use stem cells to identify underlying cellular defects that cause Angelman syndrome

New report suggests innovative approaches for better response to chemical inhalation disasters

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