Radiation Therapy News and Research

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Radiation therapy (also called radiotherapy, x-ray therapy, or irradiation) is the use of a certain type of energy (called ionizing radiation) to kill cancer cells and shrink tumors. Radiation therapy injures or destroys cells in the area being treated (the “target tissue”) by damaging their genetic material, making it impossible for these cells to continue to grow and divide. Although radiation damages both cancer cells and normal cells, most normal cells can recover from the effects of radiation and function properly. The goal of radiation therapy is to damage as many cancer cells as possible, while limiting harm to nearby healthy tissue.

Survival of head and neck cancer patients is greatly affected by coexisting ailments

Current estimates for head and neck cancer survival are largely inaccurate because they widely disregard many of the most common diseases such patients have in addition to their primary cancer, says Jay Piccirillo, M.D., a head and neck specialist at Washington University School of Medicine in St. Louis, the Siteman Cancer Center and Barnes-Jewish Hospital.

19 Nov 2008

Cytori announces seven new investigator-initiated clinical studies in Japan

All seven studies are investigator-initiated and to be performed under local and country guidelines. Cytori, who will not sponsor these studies, will continue work with country authorities, such as the Ministry of Health and Labor in Japan, to obtain specific regulatory approvals for its products.

19 Nov 2008

Gentium S.p.A. updates on phase 3 trial of Defibrotide for severe veno-occlusive disease

Gentium S.p.A. announced today interim results from an independent Data Safety Monitoring Board (DSMB) review of the Company's Phase 3 treatment trial of Defibrotide for Severe Veno-Occlusive Disease (VOD).

19 Nov 2008

CAPHOSOL shown to benefit cancer patients undergoing chemotherapy and radiation therapy

New data show that CAPHOSOL, an advanced electrolyte solution, results in low rates of oral mucositis and pain in patients with head and neck (HN) cancer who are undergoing chemotherapy and radiation therapy.

17 Nov 2008

Proton therapy may reduce serious side effect of lung cancer treatment

Patients with locally advanced lung cancer who receive chemotherapy and proton therapy, a specialized form a radiation therapy only available in a few centers in the United States, have fewer instances of a serious side effect called bone marrow toxicity than patients who receive chemotherapy and another type of radiation therapy called intensity modulated radiation therapy (IMRT), according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

16 Nov 2008

Gender found to be play important role as a prognostic factor in people diagnosed with lung cancer

Even though some combinations of gender, race and/or marital status can factor into the overall survival of nonoperative non-small cell lung cancer patients, gender is the most significant factor impacting overall survival, according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

16 Nov 2008

YM Biosciences reports on early trials of nimotuzumab in brain metastases and high-grade glioma

YM BioSciences Inc. has announced data from two clinical trials of nimotuzumab, its humanized monoclonal antibody that targets the epidermal growth factor receptor (EGFR). Preliminary results from the two trials which are evaluating nimotuzumab in combination with radiation therapy for the treatment of brain metastases and high-grade gliomas, conducted by YM's licensor, were presented at the 2008 EORTC-NCI-AACR annual meeting recently held in Geneva, Switzerland.

3 Nov 2008

Women need to be aware of changes, breast expert says

Every day, women face a barrage of headlines about breast cancer. What should they do with all of that information?

15 Oct 2008

OncoGenex achieves key regulatory milestone for lead product candidate

OncoGenex Pharmaceuticals Inc. today announced that it concluded a meeting with the U.S. Food and Drug Administration (FDA) on October 7, 2008, and that the FDA agreed that "durable pain palliation is an acceptable and desirable study endpoint" to support a product marketing approval for OGX-011 as a treatment for hormone refractory prostate cancer (HRPC).

13 Oct 2008

Lilly to acquire ImClone Systems for $6.5 billion

Eli Lilly and Company and ImClone Systems Inc. today announced that the boards of directors of both companies have approved a definitive merger agreement under which Lilly will acquire ImClone through an all cash tender offer of $70.00 per share, or approximately $6.5 billion.

6 Oct 2008

Cancer treatment by linear accelerator is a reality now in India

The first patient was successfully treated by the state-of-the-art technology in radiotherapy - linear accelerator, which began functioning last week at RR Cancer Institute and Research Centre, Sri Ram Murti Smarak Institute of Medical Sciences (SRMSIMS), Bareilly in India.

5 Oct 2008

Some cases of breast cancer overtreated

According to a new study standard radiation therapy for some breast cancer patients may not be medically required and may, therefore, be causing unnecessary serious side effects.

24 Sep 2008

One week radiation treatment for breast cancer as effective as standard 6 to 7 week course

A new type of radiation treatment rapidly speeds up treatment for some breast cancer sufferers.

24 Sep 2008

Breast MRI scan could determine need for radiation therapy

For women whose breast cancer has spread to their lymph nodes, a magnetic resonance imaging (MRI) scan could replace exploratory surgery as the method for determining whether those women need radiation therapy to treat their disease, according to a study to be presented during the annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) which opens today in Boston.

21 Sep 2008

Radiation treatment less likely for African American women fighting breast cancer

According to a new study, African American women with breast cancer who have a lumpectomy are less likely to receive radiation treatment compared to white women-the standard for early stage breast cancer.

10 Sep 2008

The Cancer Genome Atlas reports first results

The Cancer Genome Atlas (TCGA) has reported results from its first comprehensive study which focused on the deadly brain cancer glioblastoma.

8 Sep 2008

Black women less likely than white women to receive follow-up treatments after breast cancer surgery

Black women who undergo a lumpectomy surgery to treat early-stage breast cancer are less likely than their white counterparts to receive the recommended follow-up radiation therapy treatments, according to study released on Wednesday, Reuters/Boston Globe reports. Standard care after a lumpectomy includes a series of radiation treatments to ensure that all cancerous cells have been treated.

5 Sep 2008

Normalizing tumor vessels to improve chemotherapy drug delivery

Chemotherapy drugs often never reach the tumors they're intended to treat, and radiation therapy is not always effective, because the blood vessels feeding the tumors are abnormal-"leaky and twisty" in the words of the late Judah Folkman, MD, founder of the Vascular Biology program at Children's Hospital Boston.

25 Aug 2008

Brachytherapy may benefit obese prostate cancer patients

Brachytherapy, also called seed implants, may be a more beneficial treatment than surgery or external beam radiation therapy for overweight or obese prostate cancer patients, according to a study published in the August issue of the International Journal of Radiation Oncology-Biology-Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.

19 Aug 2008

Alternative vaccine strategy shows promise in prostate cancer patients

New research indicates that giving patients a continuous low dose of an immune system booster, a method known as metronomic dosing, as part of a therapeutic prostate cancer vaccine strategy is safe and produces similar immune responses and fewer side effects than the more common dosing method, which is not well tolerated by many patients. This study, led by researchers at that National Cancer Institute (NCI), part of the National Institutes of Health, was published in the Aug. 15, 2008, issue of Clinical Cancer Research.

17 Aug 2008

Radiation Therapy News and Research

Further Reading

Survival of head and neck cancer patients is greatly affected by coexisting ailments

Cytori announces seven new investigator-initiated clinical studies in Japan

Gentium S.p.A. updates on phase 3 trial of Defibrotide for severe veno-occlusive disease

CAPHOSOL shown to benefit cancer patients undergoing chemotherapy and radiation therapy

Proton therapy may reduce serious side effect of lung cancer treatment

Gender found to be play important role as a prognostic factor in people diagnosed with lung cancer

YM Biosciences reports on early trials of nimotuzumab in brain metastases and high-grade glioma

Women need to be aware of changes, breast expert says

OncoGenex achieves key regulatory milestone for lead product candidate

Lilly to acquire ImClone Systems for $6.5 billion

Cancer treatment by linear accelerator is a reality now in India

Some cases of breast cancer overtreated

One week radiation treatment for breast cancer as effective as standard 6 to 7 week course

Breast MRI scan could determine need for radiation therapy

Radiation treatment less likely for African American women fighting breast cancer

The Cancer Genome Atlas reports first results

Black women less likely than white women to receive follow-up treatments after breast cancer surgery

Normalizing tumor vessels to improve chemotherapy drug delivery

Brachytherapy may benefit obese prostate cancer patients

Alternative vaccine strategy shows promise in prostate cancer patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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