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Gut microbiome may help improve immunotherapy response in melanoma patients

Patients with malignant melanoma - whose disease has spread - are more likely to respond to immunotherapy treatment if they had greater diversity in their gut bacteria, according to new research presented at the National Cancer Research Institute's Cancer Conference in Liverpool.

6 Nov 2016

C-Path, CDISC and TransCelerate announce availability of TA Standard for Kidney Transplantation

The Clinical Data Interchange Standards Consortium, Critical Path Institute, and TransCelerate BioPharma, Inc., announce the open availability of a CDISC Therapeutic Area (TA) Standard for Kidney Transplantation.

3 Nov 2016

Study shows promise for successful ovarian transplantation in future

Approximately 11% of women worldwide suffer from premature ovarian failure. This can have many different causes: chemotherapy administered for a malignant disease might irreversibly damage the ovaries and, because of the advances in modern cancer therapy, the number of young women surviving cancer is on the increase.

2 Nov 2016

Researchers develop new way to test strength of immune response

The immune system orchestrates large and small scale attacks on innumerous targets: viruses, bacteria, cancer, but it also misfires causing allergy or autoimmune reactions.

27 Oct 2016

Sheffield Teaching Hospitals NHS Foundation Trust sees huge increase in clinical research

Sheffield Teaching Hospitals NHS Foundation Trust has seen one of the biggest rises in the number of research studies it is offering to its patients, according to a national league table of NHS research activity published by the National Institute for Health Research Clinical Research Network today (Tuesday 26 October).

27 Oct 2016

Gut microbes can modify our mood and behaviour, research reveals

If aliens were to examine a human, they would think we were just slavish organisms designed to feed microbes and carry them around.

21 Oct 2016

Novel device that uses gold nanowires may benefit biomedical professionals during medical procedures

Grown like a snowflake and sharpened with a sewing machine, a novel device by Kansas State University researchers may benefit biomedical professionals and the patients they serve during electrode and organ transplant procedures.

20 Oct 2016

Gene deletion shows new way to treat influenza

Researchers at Houston Methodist kept mice from getting the flu by removing a gene that regulates their immune system.

19 Oct 2016

Innovative procedure may improve outcomes in people with keratoconus

An innovative procedure may improve outcomes in people with a degenerative eye disease, suggest five-year results from a study presented at AAO 2016, the 120th annual meeting of the American Academy of Ophthalmology.

19 Oct 2016

San Antonio scientists aim to develop effective method for stem cell delivery to the brain

A national science publication has featured the work of San Antonio scientists aiming to develop a more effective method for delivering neural stem cells to the brain in an effort to move forward stem cell therapies to treat neurological disorders.

18 Oct 2016

Salk scientist receives NIH Pioneer Award to support innovative biomedical research

Salk Professor Juan Carlos Izpisua Belmonte has been awarded a 2016 National Institutes of Health Pioneer Award, a highly coveted grant that supports the most innovative biomedical research, for his work in stem cell biology and regeneration.

18 Oct 2016

Researchers find new path to stop metastatic growth of cancer

Investigators from the Research Institute of the McGill University Health Centre, and the Institute of Cancer Research, London, have discovered that some cancer cells can draw blood from existing mature blood vessels allowing them to continue to spread.

18 Oct 2016

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Cleveland Clinic cancer researchers receive $2.4 million grant from NIH NHLBI

The National Institutes of Health National Heart, Lung and Blood Institute has awarded a $2.4 million grant over four years to Cleveland Clinic cancer researchers Jaroslaw Maciejewski, M.D., and Richard Padgett, Ph.D., to test the hypothesis that alterations in the pattern of splicing of target genes play a major role in the establishment or progression of myelodysplastic syndromes (MDS).

14 Oct 2016

Many Canadian territories restrict access to medications for treating hepatitis C, study finds

A study conducted by Canadian and Australian researchers shows that nearly everywhere in Canada, the provinces and territories impose obstacles to reimbursement of new direct-acting antivirals (DAA) to treat hepatitis C by because of their cost.

14 Oct 2016

Science Museum acquires first 3D printed models for new Medicine Galleries

The Science Museum has acquired the first 3D printed models used by surgeons to plan a complex paediatric kidney transplant.

14 Oct 2016

Mount Sinai awarded $10 million grant to explore cellular, molecular mechanisms of GVHD

Researchers from the Icahn School of Medicine at Mount Sinai have been awarded a $10 million from the National Cancer Institute to explore the cellular and molecular mechanisms of acute graft-versus-host disease (GVHD), a common side effect that occurs after allogeneic bone marrow transplantation (BMT), and to develop novel therapeutic strategies for BMT patients with cancer that begin in the cells of blood-forming tissue or hematologic malignancies.

13 Oct 2016

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

A multi-center team of researchers are planning a clinical trial using cardiosphere-derived cells (CDCs) (a heterogeneous cluster of proliferating cardiac cells that include mesenchymal stem cells) to regenerate the tissue and improve function of the heart in patients who have suffered heart attacks (myocardial infarction, MI).

13 Oct 2016

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

In a study using Real-time intraoperative magnetic resonance imaging (RT-IMRI) to guide the transplantation of induced pluripotent stem cell (iPSC)-derived neurons into the brains of non-human primates modeled with Parkinson's disease, researchers found that RT-IMRI guidance not only allows for better visualization and monitoring of the procedure, but also helps cell survival.

13 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Transplant News and Research

Gut microbiome may help improve immunotherapy response in melanoma patients

C-Path, CDISC and TransCelerate announce availability of TA Standard for Kidney Transplantation

Study shows promise for successful ovarian transplantation in future

Researchers develop new way to test strength of immune response

Sheffield Teaching Hospitals NHS Foundation Trust sees huge increase in clinical research

Gut microbes can modify our mood and behaviour, research reveals

Novel device that uses gold nanowires may benefit biomedical professionals during medical procedures

Gene deletion shows new way to treat influenza

Innovative procedure may improve outcomes in people with keratoconus

San Antonio scientists aim to develop effective method for stem cell delivery to the brain

Salk scientist receives NIH Pioneer Award to support innovative biomedical research

Researchers find new path to stop metastatic growth of cancer

Penn researchers identify new immune system mechanism to fight against infections

Cleveland Clinic cancer researchers receive $2.4 million grant from NIH NHLBI

Many Canadian territories restrict access to medications for treating hepatitis C, study finds

Science Museum acquires first 3D printed models for new Medicine Galleries

Mount Sinai awarded $10 million grant to explore cellular, molecular mechanisms of GVHD

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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