B Cell News and Research

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Human iPS cell-derived inner ear cells may improve hereditary hearing loss

A Japanese research group has successfully grafted human iPS cell-derived inner ear cells that express human-derived proteins into the inner ears of embryonic mice.

8 Feb 2018

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Cleveland Clinic researchers have published findings in Nature Communications on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.

8 Feb 2018

Special protein improves survival and lung function of mice with influenza, study shows

GM-CSF, a protein that modifies the immune response to the flu, may also help reduce lung inflammation and improve survival during influenza, according to Penn State researchers.

8 Feb 2018

Researchers describe human blood-nerve barrier transcriptome for the first time

Human peripheral nerves -- all the nerves outside of the central nervous system -- are protected by the blood-nerve barrier. This is a tight covering of endothelial cells that maintains the microenvironment within the nerves by restricting the amounts or types of water, ions, solutes and nutrients that can reach the axons, or electric cables within the nerves, from the blood circulation system.

8 Feb 2018

New algorithm provides personalized treatment approach for patients with metastatic spine cancer

Every kind of cancer can spread to the spine, yet two physician-scientists who treat these patients describe a paucity of guidance for effectively providing care and minimizing pain.

8 Feb 2018

Research project succeeds in palliating kidney disease caused by diabetes in mice

Diabetes has become a major health problem worldwide; some estimates suggest that in twenty years' time there will be around 600 million diabetics. The disease is caused by impaired insulin secretion, which in turn hinders cell glucose uptake; as a result, sugar levels in the bloodstream remain excessively high.

8 Feb 2018

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule.

7 Feb 2018

Research could pave way for treatments to reduce risk of heart disease and stroke

The discovery of a previously unknown interaction between proteins could provide a breakthrough in the prevention of damage to healthy blood vessels.

7 Feb 2018

Study provides insight into mechanisms for increased male susceptibility to ASD

Exposure to androgens (male hormones) during brain development alters genes related to autism spectrum disorder (ASD), according to a new study published in Biological Psychiatry.

7 Feb 2018

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic.

7 Feb 2018

Scientists find new way to kill liver cancer cells

Scientists at the University of Delaware and the University of Illinois at Chicago have found a new way to kill liver cancer cells and inhibit tumor growth. First, they silence a key cellular enzyme, and then they add a powerful drug.

7 Feb 2018

Novel technology platform for custom designing bacteriophages

Bacteriophages, known informally as phages, are viruses that can attack and kill specific bacteria. They occur everywhere in the natural world. Precisely because they are matched to just one specific type of bacteria, researchers and medics hope that phages can be engineered to combat certain bacterial infections.

7 Feb 2018

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Scientists have for the first time discovered a mechanism that limits the number of "cellular janitors" in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.

7 Feb 2018

Altered immune cell clocks may contribute to metabolic diseases in shift workers

About 15 million Americans don't have a typical nine-to-five workday, and many of these--nurses, firefighters and flight attendants, among many other professions--may see their schedule change drastically one week to the next.

7 Feb 2018

Loss of coenzyme Q10 increases pre-diabetes risk

Levels of CoQ and the presence of insulin resistance were analyzed in a range of experimental laboratory settings, mouse models and samples from humans, as part of an ambitious research collaboration conducted with the University of Sydney, Victor Chang Cardiac Research Institute, Duke University School of Medicine, Garvan Institute of Medical Research, Genentech Inc. and the University of New South Wales.

7 Feb 2018

Study sheds light on Salmonella death at low temperatures

The most economical way to kill bacteria that cause common food-borne illnesses -- mostly caused by Salmonella enterica -- is heat, but, the mechanisms that kill Salmonella at lower temperatures were not fully understood until now, according to a team of researchers.

7 Feb 2018

B Cell News and Research

Human iPS cell-derived inner ear cells may improve hereditary hearing loss

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Special protein improves survival and lung function of mice with influenza, study shows

Researchers describe human blood-nerve barrier transcriptome for the first time

New algorithm provides personalized treatment approach for patients with metastatic spine cancer

Research project succeeds in palliating kidney disease caused by diabetes in mice

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

Research could pave way for treatments to reduce risk of heart disease and stroke

Study provides insight into mechanisms for increased male susceptibility to ASD

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Scientists find new way to kill liver cancer cells

Novel technology platform for custom designing bacteriophages

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Altered immune cell clocks may contribute to metabolic diseases in shift workers

Loss of coenzyme Q10 increases pre-diabetes risk

Study sheds light on Salmonella death at low temperatures

Study shows why insulin secretion does not work properly in type 2 diabetic individuals

Researchers develop novel antibody-based therapy to treat organ fibrosis

Scientists develop new system to match genetic anomalies with precision medicine treatments

Microscope technology reveals full-length serotonin receptor structure for first time

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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