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APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

Leading physiology and pharmacology researchers will speak in a four-part series centered on the gut microbiome--the microbe population living in the digestive tract--and its role in wound recovery, hypertension and nervous system function.

29 Mar 2019

New targetable vulnerability in breast cancer cells discovered

Researchers at the University of Helsinki and Karolinska Institutet have discovered new molecular mechanisms of breast cancer cell signaling that contribute to aggressive behavior of cancer cells.

29 Mar 2019

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Research efforts to comprehensively map adult human cells are in progress. But in a Perspective publishing March 28 in the journal Developmental Cell, researchers argue that there is a need to map children’s cells with the same level of granularity.

29 Mar 2019

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Scientists once thought that mammals entered adulthood with all of the neurons they would ever have, but studies from the 60s found that new neurons are generated in certain parts of the adult brain and pioneering studies from the 90s helped identify their origins and function.

29 Mar 2019

ProteoNic’s 2G UNic protein production technology licensed to Bayer

ProteoNic Biotechnology BV today announced that it has licensed its 2G UNic technology for boosting recombinant protein production to the pharmaceutical company Bayer.

29 Mar 2019

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Queen’s University Belfast and Domainex are pleased to announce that their joint project team has successfully identified novel first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP.

29 Mar 2019

Breakthrough study could lead to new treatments for sickle cell disease

In a breakthrough study of sickle cell disease, biomedical engineers in the University of Minnesota College of Science and Engineering have revealed that the building blocks of the disease are much less efficient at organizing than previously thought.

29 Mar 2019

Researchers show potential of biomimicry to grow prevascularized tissues for cardiac patches

A team led by Feng Zhao, associate professor of biomedical engineering at Michigan Technological University, recently published two new papers on best practices in engineering prevascularized tissues.

29 Mar 2019

Study reveals new way to increase population of intestinal stem cells

Cells that line the intestinal tract are replaced every few days, a high rate of turnover that relies on a healthy population of intestinal stem cells. MIT and University of Tokyo biologists have now found that aging takes a toll on intestinal stem cells and may contribute to increased susceptibility to disorders of the gastrointestinal tract.

29 Mar 2019

Walnut consumption could change gene expression in pathologically-confirmed breast cancers

New research from Marshall University links walnut consumption as a contributing factor that could suppress growth and survival of breast cancers.

29 Mar 2019

Promising new way to thwart tricky Mtb pathogen

Tuberculosis, an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective.

29 Mar 2019

Allergic reactions trigger changes in brain behavior development in unborn males and females

Researchers at the University of Maryland School of Medicine and colleagues at Ohio State University have discovered that allergic reactions trigger changes in brain behavior development in unborn males and females.

29 Mar 2019

Researchers identify 30 genes associated with schizophrenia

The research group led by Prof. Alex Schier, Director of the University of Basel's Biozentrum, has identified 30 genes associated with schizophrenia.

29 Mar 2019

Researchers discover 'taste bud cells' in mice lungs after severe bout of flu

Most people who weather an infection with influenza fully recover after a week or two. But for some, a severe case of the flu can actually reshape the architecture of their lungs and forever compromise their respiratory function.

29 Mar 2019

Cancer prevention drug also reduces virulence of H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

Study uncovers details about human immune response to dengue infection

About 40 percent of the global population is at risk for contracting dengue - the most important mosquito-borne viral infection and a close "cousin" of the Zika virus - and yet, no effective treatment or safe licensed vaccine exists.

29 Mar 2019

World’s first HIV-to-HIV kidney transplant with living donor succeeds

The world's first kidney transplant from a living HIV-positive donor to another HIV-positive person was successfully performed Monday by doctors at a Johns Hopkins University hospital.

28 Mar 2019

New strategy for potential treatment of HBV associated liver cancer

Researchers from Duke-NUS Medical School, Singapore General Hospital and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma, a commonly occurring liver cancer.

28 Mar 2019

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers have shown that cancer immunotherapy targeting the tumor biomarker epithelial cell adhesion molecule is safe and nontoxic in mice and can significantly delay tumor formation and growth.

28 Mar 2019

Cell News and Research

APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

New targetable vulnerability in breast cancer cells discovered

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

ProteoNic’s 2G UNic protein production technology licensed to Bayer

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Breakthrough study could lead to new treatments for sickle cell disease

Researchers show potential of biomimicry to grow prevascularized tissues for cardiac patches

Study reveals new way to increase population of intestinal stem cells

Walnut consumption could change gene expression in pathologically-confirmed breast cancers

Promising new way to thwart tricky Mtb pathogen

Allergic reactions trigger changes in brain behavior development in unborn males and females

Researchers identify 30 genes associated with schizophrenia

Researchers discover 'taste bud cells' in mice lungs after severe bout of flu

Cancer prevention drug also reduces virulence of H. pylori bacterium

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Study uncovers details about human immune response to dengue infection

World’s first HIV-to-HIV kidney transplant with living donor succeeds

New strategy for potential treatment of HBV associated liver cancer

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

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