Clinical Trial News and Research

RSS

Critical gaps found in pediatric medical device trials: Lack of control groups and low infant participation

Clinical trials addressing high-risk pediatric medical devices used in children.

2 Oct 2023

Wildling mice provide insights into how microbes affect allergies

The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis.

29 Sep 2023

New drug could transform how doctors treat grade 2 IDH-mutant gliomas

A top UVA Health cancer expert is highlighting how a new drug could transform how doctors treat a brain tumor that typically strikes younger people.

29 Sep 2023

Survey: Racial and ethnic minorities less likely to participate in clinical trials

A survey conducted in one cancer center's catchment area found that while a majority of respondents would be willing to participate in a clinical trial, members of racial and ethnic minority groups were significantly less likely to participate than non-Hispanic whites, according to results presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held September 29-October 2, 2023.

29 Sep 2023

NCI-sponsored cancer clinical trials become more representative of broader patient population

Compared to the year 2000, a greater proportion of NCI-sponsored early-phase clinical trial participants in 2022 were older, from minority racial/ethnic groups, and lived in historically underrepresented regions of the U.S., according to a study presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held September 29-October 2, 2023.

29 Sep 2023

Extending FDA-approved cancer drug indications requires high patient numbers, study finds

Number of patient participants needed for secondary approval of a new cancer drug.

29 Sep 2023

Mobile AI rivals specialists in diagnosing skin cancer, outperforms junior doctors

This multicenter clinical trial compared AI-powered mobile phone diagnostic tools with human medical experts in diagnosing pigmented skin cancer. The study found that the AI system was equivalent to specialists in accuracy and superior to novices, showcasing mobile technology's potential for accessible and accurate skin cancer diagnosis.

28 Sep 2023

Nicotine e-cigarettes, varenicline, and cytisine most effective for long-term smoking cessation, analysis finds

A comprehensive new analysis has found that nicotine e-cigarettes, varenicline and cytisine are the most effective options currently available for helping smokers quit long-term (going at least six months without smoking).

28 Sep 2023

Study focuses on empowering minoritized patients with chronic pain to receive best care

A new study led by a U.S. Department of Veterans Affairs, Regenstrief Institute and Indiana University School of Medicine researcher focuses on empowering minoritized patients with chronic back and other musculoskeletal pain to receive care best suited to their individual values and preferences.

28 Sep 2023

Brain compensation may delay worsening of Parkinson's symptoms

In Parkinson's disease, the cerebral cortex can take over tasks from a deeper part of the brain that has been damaged, where cells that make dopamine have been lost.

28 Sep 2023

Virtual reality vs. opioids: clinical trial of non-pharmacological pain management during burn wound care

Researchers assessed the feasibility and efficacy of virtual reality as a non-pharmaceutical intervention for managing procedural pain in adult burn patients during dressing changes compared to standard opioid-based approaches.

28 Sep 2023

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

Researchers discovered molnupiravir-associated mutational signatures in SARS-CoV-2 genomes.

27 Sep 2023

$45M awarded to develop sense-and-respond implant technology for cancer treatment

The Advanced Research Projects Agency for Health (ARPA-H) has awarded $45 million to rapidly develop sense-and-respond implant technology that could slash U.S. cancer-related deaths by more than 50%.

26 Sep 2023

Study finds mixed results for mobile health app in cardiac rehabilitation

Nearly one in three Americans wear a wearable device, like a smartwatch, to track their health and fitness.

26 Sep 2023

Stem cell transplant offers hope for patients with multiple sclerosis

Stem cells harvested from a person's own bone marrow or blood, can safely slow progression of the most common form of the autoimmune disease, multiple sclerosis, or MS as it's usually known, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

26 Sep 2023

Stem cell transplant offers hope for MS patients, study finds

Autologous hematopoietic stem cell transplantation, or aHSCT for short, is usually used to treat blood cancers, and involves harvesting stem cells from the person's own bone marrow or blood followed by chemotherapy and antibody treatment.

25 Sep 2023

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy - one that boosts T cells, and another that boosts dendritic cells - can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone.

25 Sep 2023

Kombucha tea shows promise in lowering blood sugar levels for type 2 diabetics

A recent clinical trial conducted at Georgetown University Hospital suggests that kombucha tea may hold potential as an anti-hyperglycemic agent, reducing fasting blood glucose levels in adult patients with type 2 diabetes. While the results are promising, further research with larger sample sizes is needed to solidify the health benefits of kombucha in managing diabetes.

25 Sep 2023

Breast cancer patients treated with alpelisib have elevated rates of high blood sugar

New research has uncovered elevated rates of high blood sugar, or hyperglycemia, among patients with breast cancer who are treated with the oral medication alpelisib.

25 Sep 2023

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

A clinical trial has launched to test whether early intensive immune modulation for hospitalized COVID-19 patients with relatively mild illness is beneficial.

22 Sep 2023

Clinical Trial News and Research

Critical gaps found in pediatric medical device trials: Lack of control groups and low infant participation

Wildling mice provide insights into how microbes affect allergies

New drug could transform how doctors treat grade 2 IDH-mutant gliomas

Survey: Racial and ethnic minorities less likely to participate in clinical trials

NCI-sponsored cancer clinical trials become more representative of broader patient population

Extending FDA-approved cancer drug indications requires high patient numbers, study finds

Mobile AI rivals specialists in diagnosing skin cancer, outperforms junior doctors

Nicotine e-cigarettes, varenicline, and cytisine most effective for long-term smoking cessation, analysis finds

Study focuses on empowering minoritized patients with chronic pain to receive best care

Brain compensation may delay worsening of Parkinson's symptoms

Virtual reality vs. opioids: clinical trial of non-pharmacological pain management during burn wound care

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

$45M awarded to develop sense-and-respond implant technology for cancer treatment

Study finds mixed results for mobile health app in cardiac rehabilitation

Stem cell transplant offers hope for patients with multiple sclerosis

Stem cell transplant offers hope for MS patients, study finds

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Kombucha tea shows promise in lowering blood sugar levels for type 2 diabetics

Breast cancer patients treated with alpelisib have elevated rates of high blood sugar

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer