Membrane News and Research

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Study: TMEM41B transmembrane protein is a critical factor for SARS-CoV-2 replication

A single protein that appears necessary for the COVID-19 virus to reproduce and spread to other cells is a potential weakness that could be targeted by future therapies.

10 Dec 2020

Organic hydrogels can be a promising candidate for building long-term functioning glucose biosensors

In a new study, published online in the journal American Chemical Society (ACS) Applied Polymer Materials, scientists at Texas A&M University reported they have designed a hydrogel membrane that may be used to house optical glucose sensing materials, toward building a biosensor for monitoring sugar levels in diabetics.

10 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Researchers use advanced methods to investigate structure and interactions of proteins

Michael Gross, professor of chemistry in Arts & Sciences at Washington University in St. Louis and of immunology and internal medicine at the School of Medicine, and his team are experts in footprinting proteins -- that is, using advanced methods for investigating the structure and interactions of proteins within larger molecules.

8 Dec 2020

Researchers use novel technology to prevent destruction of specific proteins inside cells

Columbia researchers have created a new technology using synthetic llama antibodies to prevent specific proteins from being destroyed inside cells.

8 Dec 2020

D614/G614 variants of SARS-CoV-2 affect neuronal transmission; G614 better at membrane fusion

The COVID-19 pandemic is showing a strong comeback after an initial reduction in the number of cases, following energetic public health interventions.

7 Dec 2020

Rice biochemist discovers hidden structure in essential metabolic machinery

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.

5 Dec 2020

Matrix-induced autologous chondrocyte implantation shows comparable benefit to therapy alternatives

Autologous chondrocyte implantation (ACI) has been used in adults with deep cartilage defects for over 30 years and has been further developed and modified over time.

5 Dec 2020

Findings about primary cilia may be relevant for transplantation therapies in diabetes

A new study from Karolinska Institutet and the Helmholtz Diabetes Research Center shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery of glucose to the insulin-producing beta cells in the pancreatic islets.

5 Dec 2020

Can melatonin help prevent severe COVID-19?

A team of researchers at the University of Toronto in Canada has found that melatonin can be an adjuvant to augment the efficacy of anti-SARS-CoV-2 vaccines. They believe that the drug is a potential “silver bullet” to combat the COVID-19 pandemic.

3 Dec 2020

New tool to predict breast cancer recurrences

A new tool combining traditional pathology with machine learning could predict which breast cancer patients actually need surgery.

3 Dec 2020

Long-range allosteric influences on SARS-COV-2-ACE2 stability and detachment

The COVID-19 pandemic is caused by SARS-CoV-2, a novel beta-coronavirus which has numerous spike proteins on its membrane.

3 Dec 2020

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

The sugar residues decorating the spike (S) protein of SARS-CoV-2 are essential to the viral-receptor binding.

3 Dec 2020

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

The COVID-19 pandemic has led to millions of deaths across the globe. The causative agent of this disease is the novel coronavirus, SARS-CoV-2.

3 Dec 2020

Novel “multitope” vaccine shows promise in the fight against COVID-19

Researchers have demonstrated the potential of a protein-peptide vaccine to protect against infection with SARS-CoV-2, the agent that causes COVID-19.

3 Dec 2020

Expansion microscopy allows imaging of cell membranes in super resolution

For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes.

2 Dec 2020

New insight into role of autophagy in controlling SARS-CoV-2 infection

A team of researchers at the University of Manitoba in Canada said that nanoparticle targeting of autophagy at the sites could be a potent tool to effectively overcome COVID-19 while preventing the common adverse effects of the drug.

2 Dec 2020

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

If there is a silver lining in cancer's chaotic biology, it's that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them.

2 Dec 2020

Researchers devise new molecular imaging strategy to observe the sperm selection process

A protein called CatSper1 may act as a molecular 'barcode' that helps determine which sperm cells will make it to an egg and which are eliminated along the way.

2 Dec 2020

UCLA, UCSF obtain FDA approval for PSMA PET imaging in men with prostate cancer

The University of California's two nationally ranked medical centers, UCSF and UCLA, and their nuclear medicine teams have obtained approval from the U.S. Food and Drug Administration to offer a new imaging technique for prostate cancer that locates cancer lesions in the pelvic area and other parts of the body to which the tumors have migrated.

2 Dec 2020

Membrane News and Research

Study: TMEM41B transmembrane protein is a critical factor for SARS-CoV-2 replication

Organic hydrogels can be a promising candidate for building long-term functioning glucose biosensors

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

Researchers use advanced methods to investigate structure and interactions of proteins

Researchers use novel technology to prevent destruction of specific proteins inside cells

D614/G614 variants of SARS-CoV-2 affect neuronal transmission; G614 better at membrane fusion

Rice biochemist discovers hidden structure in essential metabolic machinery

Matrix-induced autologous chondrocyte implantation shows comparable benefit to therapy alternatives

Findings about primary cilia may be relevant for transplantation therapies in diabetes

Can melatonin help prevent severe COVID-19?

New tool to predict breast cancer recurrences

Long-range allosteric influences on SARS-COV-2-ACE2 stability and detachment

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

SARS-CoV-2 enters the CNS via multiple routes and causes various neurological disorders

Novel “multitope” vaccine shows promise in the fight against COVID-19

Expansion microscopy allows imaging of cell membranes in super resolution

New insight into role of autophagy in controlling SARS-CoV-2 infection

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

Researchers devise new molecular imaging strategy to observe the sperm selection process

UCLA, UCSF obtain FDA approval for PSMA PET imaging in men with prostate cancer

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

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