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Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

A research group from the University of Texas in Austin described a high-yield production of a stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) that may accelerate the development of vaccines and diagnostic tests. This methodological 'tour de force' paper is currently available on the bioRxiv* preprint server.

1 Jun 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Using functional MRI to demonstrate neural suppression in autism

According to the National Autism Association, people with autism spectrum disorder (ASD) may experience sensory hypersensitivity.

29 May 2020

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Patients with advanced non-small cell lung cancer (NSCLC) and the MET exon 14 (METex14) skipping mutation had a 46.5% objective response rate to the targeted therapy drug tepotinib, as shown in a study published today in the New England Journal of Medicine and presented at the 2020 American Society of Clinical Oncology Annual Meeting ASCO20 Virtual Meeting (Abstract 9556 - Poster 322) by researchers from The University of Texas MD Anderson Cancer Center.

29 May 2020

Combination therapy does not show superior efficacy in newly diagnosed myeloma

The combination of carfilzomib, lenalidomide, and dexamethasone (KRd) did not show superior efficacy in patients with newly diagnosed myeloma absent a high-risk disease prognosis, compared with the standard of care--bortezomib, lenalidomide, and dexamethasone (VRd).

29 May 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

PCR and CRF partner to deliver practical education in virtual format

PCR and CRF are pleased to announce the creation of virtual Partners in Learning sessions that will be broadcast during the PCR e-Course (June 25-27, 2020) and CRF’s TVT Connect meeting (June 18-28, 2020).

28 May 2020

SCN study outlines impacts of targeted skills training on Canada’s regenerative medicine sector

Today, Canada’s Stem Cell Network (SCN) released a study entitled, Training Tomorrow’s Research Leaders, outlining the impacts of nearly 20 years of targeted skills training on Canada’s emergent regenerative medicine sector.

28 May 2020

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Thermo Fisher Scientific, the world leader in serving science, and Biognosys, a leading developer of next-generation proteomics solutions, announce they are continuing their collaboration to advance data independent acquisition mass spectrometry-based workflows.

From Thermo Fisher Scientific Inc. 28 May 2020

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

A recent paper by researchers from China demonstrated comparable expression levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry mediators in adults and children, suggesting that previously implied difference in viral-entry associated genes is likely not responsible for milder symptoms in children. The study is currently available on the medRxiv preprint server.

27 May 2020

Promising researchers to receive funding through AGA Research Foundation Awards Program

The American Gastroenterological Association (AGA) is excited to announce the 17 researchers selected to receive funding through the AGA Research Foundation Awards Program.

27 May 2020

Researchers develop rapid electro-optical test to identify COVID-19 carriers

Ben-Gurion University of the Negev's Prof. Gabby Sarusi has developed a one-minute electro-optical test of nose, throat, or breath samples that will identify both asymptomatic and affected carriers of the COVID-19 virus in under one minute with greater than 90% accuracy.

27 May 2020

New data may help understand the evolution of Austrian SARS-CoV-2 strains

216 SARS-CoV-2 genome sequences have now been completed and released in the framework of the "Mutational Dynamics of SARS-CoV-2 in Austria" project from CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, in close collaboration with the Medical University of Vienna, the Medical University of Innsbruck and the Austrian Agency for Health and Food Safety (AGES).

27 May 2020

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

A new federal grant will allow young scientists to delve into the mechanisms of emotional eating and preeclampsia and other disorders not considered "classic" metabolic diseases.

26 May 2020

Methods to move precision medicine from evaluation into practice and policy

Value in Health, the official journal of ISPOR - the professional society for health economics and outcomes research, announced today the publication of a series of articles focused on methods for moving from the evaluation of precision medicine into practice and policy.

26 May 2020

New AI tool could predict risk of lung cancer recurrence

Computer scientists working with pathologists have trained an artificial intelligence tool to determine which patients with lung cancer have a higher risk of their disease coming back after treatment, as part of Cancer Research UK’s landmark TRACERx study.

26 May 2020

The infection of lung stem cells may determine SARS-CoV-2 pathogenicity

A group of researchers from Russia and France has demonstrated how stem cells in the lungs can be readily infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to significant defects in their regeneration capacity and more severe coronavirus disease (COVID-19). Their manuscript is currently available on the preprint server bioRxiv.

25 May 2020

Next Generation News and Research

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

Using functional MRI to demonstrate neural suppression in autism

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Combination therapy does not show superior efficacy in newly diagnosed myeloma

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

PCR and CRF partner to deliver practical education in virtual format

SCN study outlines impacts of targeted skills training on Canada’s regenerative medicine sector

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

Promising researchers to receive funding through AGA Research Foundation Awards Program

Researchers develop rapid electro-optical test to identify COVID-19 carriers

New data may help understand the evolution of Austrian SARS-CoV-2 strains

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

Methods to move precision medicine from evaluation into practice and policy

New AI tool could predict risk of lung cancer recurrence

The infection of lung stem cells may determine SARS-CoV-2 pathogenicity

Improving IVF Treatments by Imaging Sperm Cells

New water-tasting approach could help pinpoint reserves of valuable minerals

New technique reveals potentially treatable mutations in subset of prostate cancer patients

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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