Protein C News and Research

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Over 80% of women are iron deficient by their third trimester

Iron deficiency is prevalent among pregnant women, impacting health outcomes. This study emphasizes the importance of monitoring and nutrition during pregnancy.

30 Sep 2024

Researchers identify a protein that recharges T cells for long-lasting cancer remission

Research shows Fc–IL-4 revitalizes exhausted CD8+ T cells, boosting antitumor responses and highlighting the potential of combining type 1 and type 2 immunity.

30 Sep 2024

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Researchers mapped the biological influences on 4,775 plasma proteins, revealing the interplay of modifiable and non-modifiable factors, with key implications for disease biomarkers and drug targets.

30 Sep 2024

How viral persistence and immune dysfunction drive long COVID

Study explores the biological drivers and mechanisms of long COVID, shedding light on its epidemiology and potential therapeutic interventions. It emphasizes the role of viral persistence, immune dysfunction, and coagulation in the development of this condition.

29 Sep 2024

Exploring the role of chemokines in atrial fibrillation development

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Chemokines are a subclass of cytokines, a large family of small secreted proteins that communicate via G protein-coupled heptahelical chemokine receptors on the cell surface.

29 Sep 2024

New breath-based test for lower respiratory tract infections shows 100% sensitivity in critical care settings

Researchers have developed a breath-based in vitro assay that accurately detects lower respiratory tract infections (LRTIs) by measuring neutrophil elastase activity. This non-invasive test offers high diagnostic sensitivity and could revolutionize LRTI detection.

29 Sep 2024

Innovative genomic approach identifies rare Long QT syndrome carriers

An innovative analysis of shared segments within the genome - an indication of distant "relatedness" - has identified undiagnosed cases of Long QT syndrome, a rare disorder that can lead to abnormal heart rhythms, fainting and sudden cardiac death.

27 Sep 2024

WHO announces recommended viral composition for 2025 influenza vaccines

The World Health Organization (WHO) today announced the recommendations for the viral composition of influenza vaccines for the 2025 influenza season in the southern hemisphere.

27 Sep 2024

Defective DNA repair mechanism linked to Huntington's disease progression

Researchers with McMaster University have discovered that the protein mutated in patients with Huntington's Disease doesn't repair DNA as intended, impacting the ability of brain cells to heal themselves.

27 Sep 2024

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential to tumor progression, may be effective in treating breast cancer.

27 Sep 2024

Understanding gametogenesis mechanisms in budding yeast

Sexual reproduction, a common mode of reproduction among numerous species, involves gametogenesis in which offspring are produced through fertilization, conjugation, or mating.

27 Sep 2024

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

27 Sep 2024

Scientists unravel the process of pore formation in cells

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine to form large pores in the cell membrane, which allow the release of inflammatory messengers.

26 Sep 2024

New insights into serine hydroxymethyltransferase aid cancer drug design

In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers.

26 Sep 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

Iron deficiency common among pregnant women despite supplements

When a woman becomes pregnant, her iron requirements increase almost tenfold to support fetal development as well as her own increased iron needs.

26 Sep 2024

Novel gene responsible for some inherited retinal diseases identified

Scientists at the National Institutes of Health (NIH) and their colleagues have identified a gene responsible for some inherited retinal diseases (IRDs), which are a group of disorders that damage the eye's light-sensing retina and threatens vision.

26 Sep 2024

Carotenoid phytoene shows potential in slowing Alzheimer’s plaque formation and increasing lifespan

Researchers from the Colour and Food Quality group at the Faculty of Pharmacy (University of Seville), in collaboration with Dr. Marina Ezcurra's group at the University of Kent (UK), have shown that the carotenoid phytoene increases the lifespan of the nematode Caenorhabditis elegans and can slow the onset of paralysis associated with the formation of amyloid plaques in a model of Alzheimer's disease.

26 Sep 2024

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Glioblastoma is the most common and most aggressive primary brain tumor, with an average survival after diagnosis of less than two years, and against which current treatments remain ineffective.

26 Sep 2024

New discovery could lead to improved treatments for age- and cancer-related muscle degeneration

With the global population aging rapidly, sarcopenia, a condition that affects millions of older adults and severely diminishes their quality of life, is emerging as an urgent public health issue.

26 Sep 2024