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Hopkins scientists design new mouse that mimics common form of leukemia

Johns Hopkins Kimmel Cancer Center investigators have genetically engineered a new mouse that mimics a common form of leukemia in humans. Studying the model could lead to new understanding of the disease, they say.

6 Jan 2014

Justice dept. defends birth control rule

The administration responded to a lawsuit by a group of nuns challenging how the health law exempts them from the rule.

6 Jan 2014

New study by bioethicists indicates patients give "broad endorsement" to iPSC research

In an early indication of lay opinions on research with induced pluripotent stem cells, which are stem cells made from skin or other tissues, a new study by bioethicists at Johns Hopkins University indicates that despite some ethical concerns, patients give the research "broad endorsement".

6 Jan 2014

People with severe mental illness may have higher risk for substance use

People with severe mental illness such as schizophrenia or bipolar disorder have a higher risk for substance use, especially cigarette smoking, and protective factors usually associated with lower rates of substance use do not exist in severe mental illness, according to a new study funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

5 Jan 2014

RegeneRx's Tβ4 gets FDA Orphan Drug designation for treatment of Neurotrophic Keratopathy

RegeneRx Biopharmaceuticals, Inc. announced that it has received Orphan Drug designation from U.S. FDA's Office of Orphan Products Development for its drug candidate, Thymosin beta 4 (Tβ4), for the treatment of Neurotrophic Keratopathy, a serious degenerative disease of the corneal epithelium (the outside layer of the eye).

5 Jan 2014

Viewpoints: Michael Moore finds health law affordability 'a cruel joke'; can more marketing help sell insurance?

Now that the individual mandate is officially here, let me begin with an admission: Obamacare is awful. That is the dirty little secret many liberals have avoided saying out loud for fear of aiding the president's enemies, at a time when the ideal of universal health care needed all the support it could get. ... For many people, the "affordable" part of the Affordable Care Act risks being a cruel joke. ... And yet -- I would be remiss if I didn't say this -- Obamacare is a godsend (Michael Moore, 12/31/13).

3 Jan 2014

State roundup: 'Hope' for Texas' mental health system; rural farmers staying out of health exchanges; Oregon's medical error law

A selection of health policy news from Oregon, Texas, Maryland, California, Georgia and Wisconsin.

3 Jan 2014

Discovery opens new pathways for treatment of toxoplasmosis and malaria

A newly identified protein and other proteins it interacts with could become effective targets for new drugs to control the parasite that cause toxoplasmosis, researchers led by investigators at Indiana University School of Medicine have reported.

3 Jan 2014

Biologists discover effective strategy that could prevent immune system from rejecting grafts

Biologists at UC San Diego have discovered an effective strategy that could prevent the human immune system from rejecting the grafts derived from human embryonic stem cells, a major problem now limiting the development of human stem cell therapies.

3 Jan 2014

Molecule produced by brain acts as natural defence mechanism against cannabis

Two INSERM research teams led by Pier Vincenzo Piazza and Giovanni Marsicano (INSERM Unit 862 "Neurocentre Magendie" in Bordeaux) recently discovered that pregnenolone, a molecule produced by the brain, acts as a natural defence mechanism against the harmful effects of cannabis in animals.

3 Jan 2014

Scientists discover new class of cells expressing olfactory receptors in human airways

Your nose is not the only organ in your body that can sense cigarette smoke wafting through the air. Scientists at Washington University in St. Louis and the University of Iowa have showed that your lungs have odor receptors as well.

3 Jan 2014

Chinese herbal medicine effective at alleviating acute inflammatory and nerve pain

A compound derived from a traditional Chinese herbal medicine has been found effective at alleviating pain, pointing the way to a new nonaddictive analgesic for acute inflammatory and nerve pain, according to UC Irvine pharmacology researchers.

3 Jan 2014

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance, hyperalgesia

Currently, opioids are the standard treatment for chronic pain. Patients on opioids for long periods of time become desensitized to these drugs or become paradoxically hypersensitive to pain (hyperalgesia); however, the adaptive mechanisms are not well understood.

3 Jan 2014

University of Utah discovers cellular mechanism that stops metastasis of breast cancer

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah discovered a cellular mechanism that drives the spread of breast cancer to other parts of the body (metastasis), as well as a therapy which blocks that mechanism. The research results were published online in the journal Cell Reports on January 2.

3 Jan 2014

Computer algorithm developed to identify genes that could be transformed to stop aging process

Restricting calorie consumption is one of the few proven ways to combat aging. Though the underlying mechanism is unknown, calorie restriction has been shown to prolong lifespan in yeast, worms, flies, monkeys, and, in some studies, humans.

2 Jan 2014

Cerenis' Phase IIb CHI-SQUARE study fails to meet primary endpoint in post-ACS patients

Cerenis Therapeutics, the biopharmaceutical company, today announced that its Phase IIb CHI-SQUARE (Can HDL Infusions Significantly Quicken Atherosclerosis REgression?) study did not reach its primary endpoint in post-Acute Coronary Syndrome patients.

2 Jan 2014

MD Buyline announces availability of SmartMatch to improve patient safety by tracking recalls

MD Buyline announced today the availability of SmartMatch as a value-added enhancement to its Buyline Recall Tracker recall management solution. SmartMatch helps healthcare providers ensure patient safety and mitigate risks by focusing staff on recalled products in their facilities.

2 Jan 2014

Women with high blood pressure need more optimal treatment than men

Doctors may need to treat high blood pressure in women earlier and more aggressively than they do in men, according to scientists at Wake Forest Baptist Medical Center.

2 Jan 2014

Researchers identify two novel BRAF fusions in melanomas

Stand Up To Cancer, the charitable initiative supporting ground-breaking research aimed at getting new cancer treatments to patients in an accelerated timeframe, announces that Jeffrey A. Sosman, M.D., a Stand Up To Cancer Melanoma Dream Team investigator, William Pao, M.D., Ph.D., a 2009 Stand Up To Cancer Innovative Research Grant recipient and colleagues identified two novel BRAF fusions in melanomas previously considered to be negative for molecular targets, and that melanomas with these fusions were found to be potentially sensitive to anticancer drugs called MEK inhibitors, according to a study recently published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

2 Jan 2014

Rates of smoking, drinking and drug use are higher among people with psychotic disorders

In the largest ever assessment of substance use among people with severe psychiatric illness, researchers at Washington University School of Medicine in St. Louis and the University of Southern California have found that rates of smoking, drinking and drug use are significantly higher among those who have psychotic disorders than among those in the general population.

2 Jan 2014

Drugs News and Research

Hopkins scientists design new mouse that mimics common form of leukemia

Justice dept. defends birth control rule

New study by bioethicists indicates patients give "broad endorsement" to iPSC research

People with severe mental illness may have higher risk for substance use

RegeneRx's Tβ4 gets FDA Orphan Drug designation for treatment of Neurotrophic Keratopathy

Viewpoints: Michael Moore finds health law affordability 'a cruel joke'; can more marketing help sell insurance?

State roundup: 'Hope' for Texas' mental health system; rural farmers staying out of health exchanges; Oregon's medical error law

Discovery opens new pathways for treatment of toxoplasmosis and malaria

Biologists discover effective strategy that could prevent immune system from rejecting grafts

Molecule produced by brain acts as natural defence mechanism against cannabis

Scientists discover new class of cells expressing olfactory receptors in human airways

Chinese herbal medicine effective at alleviating acute inflammatory and nerve pain

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance, hyperalgesia

University of Utah discovers cellular mechanism that stops metastasis of breast cancer

Computer algorithm developed to identify genes that could be transformed to stop aging process

Cerenis' Phase IIb CHI-SQUARE study fails to meet primary endpoint in post-ACS patients

MD Buyline announces availability of SmartMatch to improve patient safety by tracking recalls

Women with high blood pressure need more optimal treatment than men

Researchers identify two novel BRAF fusions in melanomas

Rates of smoking, drinking and drug use are higher among people with psychotic disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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