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EEG marker unlikely to predict epilepsy death

Prolonged postictal generalized electroencephalography suppression is an “inconsistent” finding in patients with epilepsy, say researchers.

30 Aug 2013

Research findings could lead to new therapeutic approaches for liver cancer

Liver cancer (Hepatocellular Carcinoma, HCC) usually arises as the result of a chronic, inflammatory liver disease. The most common causes here are excessive alcohol consumption as well as a high-fat diet and also chronic infection with the hepatitis viruses B and C. In the course of the inflammatory process, the liver cells (hepatocytes) die more frequently due to programmed cell death.

30 Aug 2013

Mayo Clinic’s programs offer hope and treatment to tobacco-dependent patients

Mayo Clinic's Nicotine Dependence Center (NDC) in Rochester is celebrating its 25th anniversary this year. As one of the first centers in the country to focus exclusively on treatments for tobacco dependence when it opened in 1988, the NDC has been at the forefront of the battle of nicotine addiction nationally as well as globally, offering the latest education and training programs, advancing research aimed at tobacco dependence interventions and offering treatment approaches to tobacco users.

30 Aug 2013

European Commission approves Stivarga tablets for treatment of patients with mCRC

Bayer HealthCare and Onyx Pharmaceuticals, Inc. (NASDAQ: ONXX) announced today that the European Commission has approved Stivarga® (regorafenib) tablets for the treatment of adult patients with metastatic colorectal cancer (mCRC).

30 Aug 2013

Statins offer great potential as anti-aging therapy

Not only do statins extend lives by lowering cholesterol levels and reducing the risks of cardiovascular disease, but new research in the September 2013 issue of The FASEB Journal suggests that they may extend lifespans as well. Specifically, statins may reduce the rate at which telomeres shorten, a key factor in the natural aging process. This opens the door for using statins, or derivatives of statins, as an anti-aging therapy.

30 Aug 2013

Glucose monitoring systems detect RBC and other interferents in burn patients blood

Glucose monitoring systems with an autocorrect feature that can detect red blood cells (hematocrit), vitamin C and other common interferents in burn patients' blood are better for monitoring care, a pilot study conducted by UC Davis researchers at the School of Medicine and College of Engineering has found.

30 Aug 2013

Head, neck cancer patients receiving radiation complied with SPP likely to suffer side effects

A study from UCLA's Jonsson Comprehensive Cancer Center (JCCC) has found that head and neck cancer patients receiving radiation as part of their treatment were less likely to suffer unwanted side effects such as worsening of diet, need for a feeding tube, or narrowing of the throat passage if they complied with a set of prescribed swallowing exercises called a swallow preservation protocol (SPP) during therapy.

30 Aug 2013

Study provides first genomic characterization of remission in juvenile rheumatoid arthritis patients

More children with juvenile rheumatoid arthritis are experiencing remission of their symptoms, thanks to new biological therapies, but the remission is not well-understood. A new study published today in Arthritis Research & Therapy provides the first genomic characterization of remission in juvenile rheumatoid arthritis patients.

30 Aug 2013

Researchers receive $5M grant from agency to advance stem cell technologies in segmental bone defects

A Cedars-Sinai team of researchers led by principal investigator Dan Gazit, PhD, DMD, has been awarded a $5.18 million grant from California's stem cell research agency to advance stem cell technologies in segmental bone defects, a complex medical problem caused by large portions of bone tissue loss.

30 Aug 2013

Researchers receive $3M R01 award to test new approach to treating brain tumors

With a five-year, $3 million R01 award from the National Institutes of Health, through the National Cancer Institute, a team of researchers led by Gregory Fischer, PhD, assistant professor of mechanical engineering and robotics engineering at Worcester Polytechnic Institute and director of WPI's Automation and Interventional Medicine Laboratory, will test a new, minimally invasive approach to treating brain tumors that promises to accurately destroy malignant tissue while leaving surrounding tissue unaffected.

30 Aug 2013

Some insurers refusing to pay for proton-beam cancer therapy

Blue Shield of California joins two other insurers who contend that other cancer treatments are just as good, and far less expensive.

30 Aug 2013

Researchers identify mutation in CNGB1 gene causing PRA in Phalene and Papillon

Professor Hannes Lohi's research group at the University of Helsinki and Folkh-lsan Research Center, Finland, has identified a mutation in CNGB1 gene, causing progressive retinal atrophy (PRA) in the Phalene and Papillon dog breeds.

30 Aug 2013

Stem cell researchers receive Early Translational research awards from CIRM

Four prominent researchers from UCLA's Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational research awards totaling approximately $13 million from the California Institute for Regenerative Medicine (CIRM) the state stem cell agency. The UCLA researchers received four of the 12 total awards; no other applicant institution received more than one award.

30 Aug 2013

BP and headache drug effectively speeds up treatment of TB

Infectious disease experts at Johns Hopkins have found, in studies in mice, that a drug better known as a treatment for high blood pressure and headaches effectively speeds up treatment of TB when added to the standard, daily antibiotic regimen. Test animals were cured in four months instead of the usual six.

30 Aug 2013

Diabetic patients could benefit from breakthrough cell study

Diabetic patients could benefit from a breakthrough that enables scientists to take cells from the pancreas and change their function to produce insulin.

30 Aug 2013

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team lead by researchers at The University of Texas MD Anderson Cancer Center reported online today in the journal Cancer Cell.

30 Aug 2013

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

First Edition: August 29, 2013

Today's headlines include reports about ongoing fiscal fights surrounding efforts to raise the nation's debt limit and to defund the health law. Also, the White House enlists former President Bill Clinton to help spread the word about the overhaul.

29 Aug 2013

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Pharmacyclics, Inc. (Nasdaq: PCYC) today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing its New Drug Application (NDA) for the investigational oral Bruton's tyrosine kinase (BTK) inhibitor ibrutinib, for two B-cell malignancy indications: previously treated mantle cell lymphoma (MCL) and previously treated chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).

29 Aug 2013

Reformulated OxyContin®: an interview with Dr. Paul Coplan, Executive Director, Risk Management and Epidemiology, Purdue Pharma

OxyContin contains oxycodone, which is an opioid agonist. It is used for the management of moderate to severe pain when a constant opioid analgesic is needed for a prolonged period of time.

29 Aug 2013

Therapy News and Research

EEG marker unlikely to predict epilepsy death

Research findings could lead to new therapeutic approaches for liver cancer

Mayo Clinic’s programs offer hope and treatment to tobacco-dependent patients

European Commission approves Stivarga tablets for treatment of patients with mCRC

Statins offer great potential as anti-aging therapy

Glucose monitoring systems detect RBC and other interferents in burn patients blood

Head, neck cancer patients receiving radiation complied with SPP likely to suffer side effects

Study provides first genomic characterization of remission in juvenile rheumatoid arthritis patients

Researchers receive $5M grant from agency to advance stem cell technologies in segmental bone defects

Researchers receive $3M R01 award to test new approach to treating brain tumors

Some insurers refusing to pay for proton-beam cancer therapy

Researchers identify mutation in CNGB1 gene causing PRA in Phalene and Papillon

Stem cell researchers receive Early Translational research awards from CIRM

BP and headache drug effectively speeds up treatment of TB

Diabetic patients could benefit from breakthrough cell study

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

First Edition: August 29, 2013

FDA approves NDA filing for ibrutinib inhibitor in two B-cell malignancies

Reformulated OxyContin®: an interview with Dr. Paul Coplan, Executive Director, Risk Management and Epidemiology, Purdue Pharma

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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