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Macrophage nanosponges offer promising solution for effectively managing sepsis

A team of researchers at the University of California San Diego has developed macrophage "nanosponges" that can safely absorb and remove molecules from the bloodstream that are known to trigger sepsis.

4 Jan 2018

Study reveals a loophole in treatment of chronic lymphocytic leukemia

A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients.

4 Jan 2018

Researchers develop new compound that inhibits growth of melanoma cells

An international team of researchers has developed a novel compound that successfully inhibits growth of melanoma cells by targeting specific epigenetic modifying proteins in these cells.

4 Jan 2018

Scientists discover mechanism that amplifies autoimmune reaction in early stage islet autoimmunity

Scientists at Helmholtz Zentrum München have discovered a mechanism that amplifies the autoimmune reaction in an early stage of pancreatic islet autoimmunity prior to the progression to clinical type 1 diabetes.

4 Jan 2018

Newly solved glucagon receptor structure provides most accurate template for drug design

Class B G protein-coupled receptors (GPCRs) exert essential action in hormonal homeostasis and are important therapeutic targets for a variety of diseases including metabolic disorders such as type 2 diabetes.

4 Jan 2018

Researchers optimize method to increase resolution of proteomic analysis

One of the key challenges of proteomics, the study of all proteins expressed by a cell or organism, is managing to distinguish between molecules that are structurally different yet have the same mass.

4 Jan 2018

Scientists show how alcohol exposure leads to permanent genetic damage

Scientists have shown how alcohol damages DNA in stem cells, helping to explain why drinking increases your risk of cancer, according to research part-funded by Cancer Research UK and published in Nature today (Wednesday).

4 Jan 2018

Genetic labeling helps researchers track behavior of blood cells

By tagging bone marrow cells of mice with a genetic label, or barcode, researchers were able to track and describe the family tree of individual blood cells as they form in their natural environment.

4 Jan 2018

Genetic changes help mosquitoes to develop pesticide resistance

For decades, chemical pesticides have been the most important way of controlling insects like the Anopheles mosquito species that spreads malaria to humans.

4 Jan 2018

Powerful imaging technique sheds light on how the brain responds to vascular injury

Pericytes, a little-understood type of cell on the brain's blood vessels, grow into the empty space left when neighboring pericytes die, report researchers at the Medical University of South Carolina in a January 2nd, 2018 article in Cell Reports.

4 Jan 2018

Researchers grow hairy skin using mouse stem cells

Indiana University School of Medicine researchers have cultured the first lab-grown skin tissue complete with hair follicles.

3 Jan 2018

Unique mechanism of drug resistance found in pandemic cholera

Cholera is a devastating disease for millions worldwide, primarily in developing countries, and the dominant type of cholera today is naturally resistant to one type of antibiotic usually used as a treatment of last resort.

3 Jan 2018

'Thunder' protein activity may be associated with behavioral disorders like schizophrenia

Researchers at Johns Hopkins Medicine report they have identified rare genetic variations in a protein called Thorase, which is responsible for breaking down receptors at the connections between neurons in the brain.

3 Jan 2018

Generic skin cream may reduce squamous cell carcinoma risk

New results from a clinical trial involving more than 900 military veterans at high risk for keratinocyte carcinoma skin cancer provides evidence that using the generic skin cream fluorouacil 5 percent for two to four weeks may reduce the risk of a squamous cell carcinoma (SCC) needing surgery by 75 percent within a year.

3 Jan 2018

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Attempts to eradicate cancer are often compared to a "moonshot" -- the successful effort that sent the first astronauts to the moon.

3 Jan 2018

Study suggests potential means of stalling or even reversing diabetes-related blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness.

3 Jan 2018

Advanced live cell imaging reveals brain’s response to blood vessel injury

Live cell imaging and laser beam ablation reveals the damage response of pericytes surrounding blood vessels in the brain.

3 Jan 2018

Researchers discover way to enhance effectiveness and safety of sonogenetics

Researchers at Duke University have discovered a way to enhance the effectiveness and safety of sonogenetics or ultrasonic modulation, emerging techniques that use sound waves to control the behavior of individual neurons or to promote tissue growth and wound healing in other cells.

3 Jan 2018

Researchers use Nobel prize-winning technology to zoom in and see vital kidney protein

Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones.

3 Jan 2018

Spider's web inspires new device that could revolutionize management of type 1 diabetes

For the more than 1 million Americans who live with type 1 diabetes, daily insulin injections are literally a matter of life and death. And while there is no cure, a Cornell University-led research team has developed a device that could revolutionize management of the disease.

3 Jan 2018

B Cell News and Research

Macrophage nanosponges offer promising solution for effectively managing sepsis

Study reveals a loophole in treatment of chronic lymphocytic leukemia

Researchers develop new compound that inhibits growth of melanoma cells

Scientists discover mechanism that amplifies autoimmune reaction in early stage islet autoimmunity

Newly solved glucagon receptor structure provides most accurate template for drug design

Researchers optimize method to increase resolution of proteomic analysis

Scientists show how alcohol exposure leads to permanent genetic damage

Genetic labeling helps researchers track behavior of blood cells

Genetic changes help mosquitoes to develop pesticide resistance

Powerful imaging technique sheds light on how the brain responds to vascular injury

Researchers grow hairy skin using mouse stem cells

Unique mechanism of drug resistance found in pandemic cholera

'Thunder' protein activity may be associated with behavioral disorders like schizophrenia

Generic skin cream may reduce squamous cell carcinoma risk

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Study suggests potential means of stalling or even reversing diabetes-related blindness

Advanced live cell imaging reveals brain’s response to blood vessel injury

Researchers discover way to enhance effectiveness and safety of sonogenetics

Researchers use Nobel prize-winning technology to zoom in and see vital kidney protein

Spider's web inspires new device that could revolutionize management of type 1 diabetes

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