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A new approach to selectively turn on gene therapies in target cells

Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells.

28 Oct 2021

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

Kawasaki disease (KD) is rare, with fewer than 6,000 diagnosed cases per year in the United States. It is most common in infants and young children and causes inflammation in the walls of some blood vessels in the body.

27 Oct 2021

NIH invests $74.5 million to advance data science research and spur health discoveries across Africa

The National Institutes of Health is investing about $74.5 million over five years to advance data science, catalyze innovation and spur health discoveries across Africa.

26 Oct 2021

UCL researchers record sharpest images ever of living bacteria

The sharpest images ever of living bacteria have been recorded by UCL researchers, revealing the complex architecture of the protective layer that surrounds many bacteria and makes them harder to be killed by antibiotics.

25 Oct 2021

Researchers reveal mechanism which allows antibiotics like penicillin to kill MRSA

The mechanism which allows β-lactam antibiotics, including penicillin, to kill MRSA has been revealed for the first time.

25 Oct 2021

Study finds link between genes and amount of bacterial toxins in the blood

Lipopolysaccharide, a virulence factor produced by bacteria, is a toxin that can cause a systemic inflammation via the circulation. In a recently completed study, genetic markers were discovered which are associated with a heightened lipopolysaccharide level in the blood.

25 Oct 2021

Study findings may lead to new treatments to fight deadly C. difficile infections

A University of California, Irvine-led study suggests that the glucosyltransferase domain (GTD) is an ideal molecular target for therapeutic interventions for Clostridioides difficile infection (CDI). These findings may lead to new treatments to fight this deadly disease.

22 Oct 2021

Machine learning approach effective in predicting antibiotic resistance spread

Genes aren't only inherited through birth. Bacteria have the ability to pass genes to each other, or pick them up from their environment, through a process called horizonal gene transfer, which is a major culprit in the spread of antibiotic resistance.

22 Oct 2021

Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Researchers tested analogs of disulfiram on SARS-CoV-2 Mpro and PLpro to find more efficient and effective inhibitors that take advantage of disulfiram’s mechanism of binding to the cysteine residue.

22 Oct 2021

Bacteria defend themselves against viral predators with exchangeable genetic elements

Bacterial viruses, so-called phages, destroy bacteria. Bacteria are constantly exposed to viral attacks. A research team led by Martin Polz, a microbiologist at the University of Vienna, has now studied how bacteria defend themselves against viral predators.

22 Oct 2021

Study finds distinct lower airways in children with cystic fibrosis

In the largest study of its kind, researchers found that the lower airways in children with cystic fibrosis (CF) have a higher burden of infection, more inflammation and lower diversity of microorganisms, compared to children with other illnesses who also have lung issues.

21 Oct 2021

Red blood cells play a much larger role in the immune system than previously thought

New research has revealed that red blood cells function as critical immune sensors by binding cell-free DNA, called nucleic acid, present in the body's circulation during sepsis and COVID-19, and that this DNA-binding capability triggers their removal from circulation, driving inflammation and anemia during severe illness and playing a much larger role in the immune system than previously thought.

20 Oct 2021

Cat bacteria likely to form the basis for novel therapeutics against severe skin infections

Researchers at University of California San Diego School of Medicine used bacteria found on healthy cats to successfully treat a skin infection on mice. These bacteria may serve as the basis for new therapeutics against severe skin infections in humans, dogs and cats.

20 Oct 2021

Study reveals potential new approach to fight urinary tract infections

Identifying the dynamic events occurring during urinary tract infections (UTI) has revealed a new potential strategy to combat this condition, considered the most common type of infection.

19 Oct 2021

Researchers reveal the mechanism of artificial chromosome formation in C. elegans' embryos

A research team led by Dr Karen Wing Yee YUEN, Associate Professor from the School of Biological Sciences at the University of Hong Kong (HKU), revealed the mechanism of artificial chromosome (AC) formation in the embryos of the model organism Caenorhabditis elegans, a 1-mm long, transparent nematode.

18 Oct 2021

Two defense systems in bacteria work in a complementary manner to protect from viruses

A new study led by a team of bioscientists from Durham University, UK, in collaboration with University of Liverpool, Northumbria University and New England Biolabs, hopes to exploit newly characterized defense systems in bacteria to compare changes to the human genome.

18 Oct 2021

Does vitamin D deficiency increase the risk of SARS-CoV-2 infections?

A recent study posted to the medRxiv* preprint server attempted to understand the relationship between vitamin D levels and COVID-19 by studying a population of UK healthcare workers who exhibited symptoms for COVID-19.

17 Oct 2021

Nasal photodisinfection therapy for COVID-19 patients may reduce the severity of lower tract respiratory disease

Research on the efficacy of nasal photodisinfection therapy for treating asymptomatic and early stage COVID-19 patients has found that it may reduce the severity of lower tract respiratory disease.

15 Oct 2021

RUDN study reveals macrophage dynamics in the regenerating liver after resection

RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis. The results are published in the Biomedicine.

15 Oct 2021

Instability in gut microbiota associated with COVID-19-related complications and mortality, study finds

Researchers from Germany recently analyzed saliva and fecal samples from SARS-CoV-2 infected and post-COVID-19 patients and controls while considering multiple influencing factors during hospitalization. This study is available on the bioRxiv* preprint server.

13 Oct 2021

Bacterial News and Research

A new approach to selectively turn on gene therapies in target cells

Studies test intravenous immunoglobulin for treatment of Kawasaki disease and MIS-C

NIH invests $74.5 million to advance data science research and spur health discoveries across Africa

UCL researchers record sharpest images ever of living bacteria

Researchers reveal mechanism which allows antibiotics like penicillin to kill MRSA

Study finds link between genes and amount of bacterial toxins in the blood

Study findings may lead to new treatments to fight deadly C. difficile infections

Machine learning approach effective in predicting antibiotic resistance spread

Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Bacteria defend themselves against viral predators with exchangeable genetic elements

Study finds distinct lower airways in children with cystic fibrosis

Red blood cells play a much larger role in the immune system than previously thought

Cat bacteria likely to form the basis for novel therapeutics against severe skin infections

Study reveals potential new approach to fight urinary tract infections

Researchers reveal the mechanism of artificial chromosome formation in C. elegans' embryos

Two defense systems in bacteria work in a complementary manner to protect from viruses

Does vitamin D deficiency increase the risk of SARS-CoV-2 infections?

Nasal photodisinfection therapy for COVID-19 patients may reduce the severity of lower tract respiratory disease

RUDN study reveals macrophage dynamics in the regenerating liver after resection

Instability in gut microbiota associated with COVID-19-related complications and mortality, study finds

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