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Johns Hopkins researchers identify new marker for early detection of colorectal cancers

Johns Hopkins researchers have identified a protein involved in cell proliferation and the development of new blood vessels that could serve as a marker for the early detection of colorectal cancers.

7 Jan 2019

A Light Source in Quantitative Analysis: What Role Does it Play?

In this interview, Claudia Jaffe discusses the importance of illuminators in microscopy and the different types of light used in life science research.

From Lumencor, Inc 7 Jan 2019

Scavenging molecule offers long-lasting protection against toxic nerve agents in rodents

For the first time, scientists have created a scavenging molecule that provides long-lasting preventative protection against toxic nerve agents in rodents.

3 Jan 2019

Researchers review applications, properties, and pharmacological potentials of rose hip

The genus Rosa from family Rosaceae is one of the most widespread species from the family. One species, rose hip, is known as a good source of different types of micronutrients and phytochemicals such as phenolic acids, tannins, and flavonoids. It is known as a traditional treatment in folk medicine.

28 Dec 2018

Scientists discover two therapies that slow progression of pediatric leukemia in mice

Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the final paper published Dec. 20 in Genes & Development.

24 Dec 2018

Study finds how pyruvate helps improve cardiac output in pediatric patients with LCOS

Can pyruvate, the end product of glycolysis, help improve cardiovascular function in children who have cardiopulmonary bypass surgery and suffer from low cardiac output syndrome? This question is one that Rafael Jaimes, Ph.D., a staff scientist at Children's National Heart Institute, a division of Children's National Health System, is studying, thanks to a two-year grant from the American Heart Association.

19 Dec 2018

Researchers synthesize new compound that inhibits replication of hepatitis C virus

A new compound that inhibits the replication of hepatitis C virus in several stages of its lifecycle - and is also capable of acting on bacteria, fungi and cancer cells - has been synthesized by researchers at São Paulo State University in Brazil.

19 Dec 2018

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

Developing the Next Generation of Water-soluble DREADDs

An interview with James Flanaghan, discussing the uses of DREADDs in neurobiological research and the advantages of water-soluble ligands.

From Hello Bio 19 Dec 2018

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

Study may identify new diagnostics and treatment option for CVD

Forty-two percent of all deaths in the United States are related to cardiovascular disease. According to the Global Cardiovascular Drugs Market Forecast, by 2030 the number of deaths from CVD will rise to 23.6 million per year in the U.S. alone.

19 Dec 2018

Researchers discover promising new compound against Buruli ulcer

Buruli ulcer - one of the most neglected among the NTDs - is a debilitating and stigmatizing disease. Affecting mainly children in West and Central Africa, the chronic disease results in devastating skin lesions and can lead to permanent disfigurement and long-term disabilities.

18 Dec 2018

New compound blocks genetic cause of familial ALS and frontotemporal dementia

Since the ice bucket challenge went viral in 2014, raising awareness and funding for ALS research, scientists have learned much about a disease that disconnects muscles from nerves, leading to muscle atrophy and eventual death. Their ultimate goal is to create medications capable of stopping ALS in its tracks.

18 Dec 2018

A promising, effective vaccine for common respiratory disease

Skin vaccination using a microneedle patch that contains the inactivated respiratory syncytial virus (RSV) and a compound that stimulates immune responses to the virus has been found to enhance protection against this serious disease and reduce inflammation in the body after exposure to the virus, according to a study led by Georgia State University.

18 Dec 2018

A Story of Innovative Molecules: From Machines to Cyclic Compounds

2016 Nobel Laureate in Chemistry Fraser Stoddart outlines his research involving mechanically interlocked molecules and molecular machines, and introduces the work of some of the students in his lab, to be discussed at Pittcon 2018.

From Pittcon 17 Dec 2018

CTF along with NTAP and Sage announce first-ever open data portal for neurofibromatosis

The Children's Tumor Foundation, together with the Neurofibromatosis Therapeutic Acceleration Program and Sage Bionetworks, has announced the first-ever open data portal for scientific research results in the field of neurofibromatosis.

17 Dec 2018

New drug shows promise in treating sarcomas

A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports.

14 Dec 2018

UA scientists uncover biological processes leading to rare brain disorder in babies

Babies born with pontocerebellar hypoplasia type Ib often do not survive past one year. Born with an underdeveloped brain, infants struggle to move, feed and even breathe.

14 Dec 2018

Recent developments and challenges in hMAT inhibitors

Zhu et al. have reviewed the recent developments in the knowledge about the binding, inhibitory mechanisms and structure-activity relationships of hSERT, hNET and hDAT, which are primary human monoamine transporters hMATs.

14 Dec 2018

Study finds drug targets for Ebola, Dengue, and Zika viruses

No drugs are currently available to treat Ebola, Dengue, or Zika viruses, which infect millions of people every year and result in severe illness, birth defects, and even death. New research from the Gladstone Institutes and UC San Francisco may finally change that. Scientists identified key ways the three viruses hijack the body's cells, and they found at least one potential drug that can disrupt this process in human cells.

13 Dec 2018

Compound News and Research

Johns Hopkins researchers identify new marker for early detection of colorectal cancers

A Light Source in Quantitative Analysis: What Role Does it Play?

Scavenging molecule offers long-lasting protection against toxic nerve agents in rodents

Researchers review applications, properties, and pharmacological potentials of rose hip

Scientists discover two therapies that slow progression of pediatric leukemia in mice

Study finds how pyruvate helps improve cardiac output in pediatric patients with LCOS

Researchers synthesize new compound that inhibits replication of hepatitis C virus

Active ingredient in eye drops shows promise for treating aggressive blood cancer

Developing the Next Generation of Water-soluble DREADDs

Potential combination therapy against rare disease of the bone marrow could improve treatment

Study may identify new diagnostics and treatment option for CVD

Researchers discover promising new compound against Buruli ulcer

New compound blocks genetic cause of familial ALS and frontotemporal dementia

A promising, effective vaccine for common respiratory disease

A Story of Innovative Molecules: From Machines to Cyclic Compounds

CTF along with NTAP and Sage announce first-ever open data portal for neurofibromatosis

New drug shows promise in treating sarcomas

UA scientists uncover biological processes leading to rare brain disorder in babies

Recent developments and challenges in hMAT inhibitors

Study finds drug targets for Ebola, Dengue, and Zika viruses

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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