Sclerosis News and Research

RSS

New research may have profound impact on future development of anti-depressant medications

Major depression, which afflicts one in six people at some point in their life, is the leading global cause of disability - surpassing cardiovascular and respiratory diseases, cancer and HIV/AIDS combined.

22 Oct 2015

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

Dietary fatty acids affect the development and progression of autoimmune chronic-inflammatory diseases such as multiple sclerosis. In a collaborative study between the Departments of Neurology at the Ruhr-Universität Bochum (St. Josef-Hospital) and the Friedrich Alexander Universtiy Erlangen, researchers now found that long-chain fatty acids promote the development and propagation of CNS reactive immune cells in the intestinal wall. On the contrary, short-chain fatty acids promote the development and propagation of regulatory cells in the immune system.

22 Oct 2015

RUCDR Infinite Biologics awarded $6 million grant from NINDS

The National Institute of Neurological Disorders and Stroke has awarded a five-year grant worth up to $6,034,323 to RUCDR Infinite Biologics, a unit of Rutgers' Human Genetics Institute of New Jersey. RUCDR, which is located on Rutgers' Busch Campus in Piscataway, is the world's largest university-based biorepository.

20 Oct 2015

Asterias’ Phase 1/2a study evaluates dose escalation of AST-OPC1 for cervical spinal cord injury

Asterias Biotherapeutics, Inc. (NYSE MKT: AST), a biotechnology company focused on the emerging field of regenerative medicine, today announced that its Data Monitoring Committee has reviewed the initial safety data from all three patients in the first cohort and has recommended dose escalation to the second cohort.

20 Oct 2015

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

Glutamate imaging may guide surgery in ‘nonlesional’ epilepsy

Glutamate imaging may be capable of identifying the focus of epileptic seizures in patients who appear to have nonlesional epilepsy on standard imaging techniques, researchers report in Science Translational Medicine.

16 Oct 2015

Seizure control improves for TSC patients undergoing more extensive surgery

Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery, reports the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

16 Oct 2015

OHSU designs new iPhone app to advance melanoma research

Oregon Health & Science University today released an iPhone app designed to advance melanoma research by giving users the ability to accurately measure and monitor moles, and contribute photos of how their potential trouble spots evolve over time.

16 Oct 2015

GATE opens for generic equivalent to glatiramer acetate in MS

Findings from the GATE study have shown equivalent efficacy and tolerability for a generic version of glatiramer acetate to that of the original brand version in the treatment of relapsing–remitting multiple sclerosis.

15 Oct 2015

Researchers uncover how small heat shock protein interacts with other proteins

In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich and the Helmholtz Zentrum Muenchen have now uncovered how the protein interacts with other proteins.

15 Oct 2015

Having a high stress job may increase risk of stroke

Having a high stress job may be linked to a higher risk of stroke, according to an analysis of several studies. The meta-analysis is published in the October 14, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Oct 2015

Merck unveils new global brand as a science and technology company

Merck, a leading science and technology company, today announced the relaunch of its brand identity. The fundamental revision of the visual appearance as well as the introduction of a new logo reflect the transformation into a global science and technology company. At the same time, the brand architecture at business level has been simplified. Outside the United States and Canada, the company will operate uniformly as Merck.

15 Oct 2015

Brain areas linked to social behaviors underdeveloped in youths with high functioning ASD

A team of UCLA scientists has found that brain areas linked to social behaviors are both underdeveloped and insufficiently networked in youths with high functioning autism spectrum disorder (ASD) compared to study participants without ASD.

14 Oct 2015

Small heat shock protein as model for Alzheimer’s medication

In Alzheimer’s disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München have now uncovered how the protein interacts with other proteins.

13 Oct 2015

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Chronic pain results from disease or trauma to the nervous system. Damaged nerve fibres with heightened responses to normal stimuli send incorrect messages to pain centres in the brain. This phenomenon, called "peripheral and central sensitization" is one of the key mechanisms involved in the condition which touches people with diabetes, cancer, and those suffering from multiple sclerosis, among others.

12 Oct 2015

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS). This is the first demonstration that introduction of blood in the healthy brain is sufficient to cause peripheral immune cells to enter the brain, which then go on to cause brain damage.

12 Oct 2015

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Three phase III studies being presented at the European Committee for Treatment Research in Multiple Sclerosis congress demonstrate that treating MS with ocrelizumab reduces relapse rate and delay onset of disability progression compared to interferon beta-1a in relapsing forms of MS and disability progression in primary progressive MS compared to placebo.

12 Oct 2015

Role for endogenous retrovirus proposed in ALS pathogenesis

Expression of the human endogenous retrovirus-K is upregulated in some patients with sporadic amyotrophic lateral sclerosis and causes degeneration of motor neurons when overexpressed in mice, research shows.

9 Oct 2015

Daclizumab HYP superior to interferon in relapsing–remitting MS

The DECIDE study shows that 4-weekly daclizumab high-yield process reduces disease activity in patients with relapsing–remitting multiple sclerosis more effectively than weekly interferon beta-1a, albeit at the cost of more adverse effects.

8 Oct 2015

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Mallinckrodt plc, a leading specialty biopharmaceutical company, today announced that data from a pilot study for its H.P. Acthar Gel (repository corticotropin injection) will be presented at the American College of Rheumatology 2015 Annual Meeting to be held November 7-11 in San Francisco.

8 Oct 2015

Sclerosis News and Research

New research may have profound impact on future development of anti-depressant medications

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

RUCDR Infinite Biologics awarded $6 million grant from NINDS

Asterias’ Phase 1/2a study evaluates dose escalation of AST-OPC1 for cervical spinal cord injury

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Glutamate imaging may guide surgery in ‘nonlesional’ epilepsy

Seizure control improves for TSC patients undergoing more extensive surgery

OHSU designs new iPhone app to advance melanoma research

GATE opens for generic equivalent to glatiramer acetate in MS

Researchers uncover how small heat shock protein interacts with other proteins

Having a high stress job may increase risk of stroke

Merck unveils new global brand as a science and technology company

Brain areas linked to social behaviors underdeveloped in youths with high functioning ASD

Small heat shock protein as model for Alzheimer’s medication

Study opens new doors to research possible treatment for patients suffering from neuropathic pain

Single drop of blood in the brain can activate autoimmune response akin to multiple sclerosis

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Role for endogenous retrovirus proposed in ALS pathogenesis

Daclizumab HYP superior to interferon in relapsing–remitting MS

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Latest News