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Confocal microscopy may help identify biomarkers for chemotherapy-induced neuropathy

A University of Arizona Comprehensive Cancer Center researcher received a $2.4 million National Cancer Institute grant to develop a noninvasive, confocal microscope to examine nerve endings of cancer patients with chemotherapy-induced peripheral neuropathy in the hopes of identifying potential biomarkers for the disease.

22 May 2025

Integrating phytomedicine and nanotechnology in managing COVID-19 related heart disease

Acute coronary syndrome (ACS) in patients with SARS-CoV-2 infection represents a critical intersection of viral-induced inflammation and cardiovascular pathology.

22 May 2025

Cutting back on sugary drinks may protect men’s fertility, review finds

Regular consumption of sugar-sweetened beverages is associated with lower sperm count, motility, and increased DNA damage, potentially impairing male reproductive health. This narrative review highlights dose-response effects, mechanisms, and research gaps, calling for further studies on diverse populations.

22 May 2025

Metabolite profiles in spinal fluid predict mortality in tuberculous meningitis

Radboudumc researchers Kirsten van Abeelen, Edwin Ardiansyah, Sofiati Dian, Vinod Kumar, Reinout van Crevel and Arjan van Laarhoven used metabolomics to study cerebrospinal fluid (CSF) samples from tuberculous meningitis patients in Vietnam and Indonesia, with long-standing collaborators from Bandung and Jakarta (Indonesia), the Broad Institute (Boston) and the Oxford University Research Unit in Ho Chi Minh City (Vietnam).

22 May 2025

Guideline-directed medical therapy boosts survival in the oldest heart attack patients

Researchers have found that prescribing guideline-directed medical treatment (GDMT), regardless of the number of medications, can improve survival rates in patients 90 years of age and older following their first heart attack, with the greatest benefit observed in patients who received all four recommended post-acute myocardial infarction (AMI) therapies.

22 May 2025

Understanding how cholera bacteria resist phage predation

When we think of cholera, most of us picture contaminated water and tragic outbreaks in vulnerable regions. But behind the scenes, cholera bacteria are locked in a fierce, microscopic war-one that could shape the course of pandemics.

22 May 2025

Meta analysis highlights prognostic role of circPVT1 in solid tumors

circPVT1 has emerged as a key regulator in disease progression and clinical outcomes. However, its prognostic relevance and association with clinicopathological parameters in solid malignancies remain to be fully elucidated.

22 May 2025

New AI blood test tracks pancreatic cancer treatment response

An artificial intelligence technique for detecting DNA fragments shed by tumors and circulating in a patient's blood, developed by Johns Hopkins Kimmel Cancer Center investigators, could help clinicians more quickly identify and determine if pancreatic cancer therapies are working.

22 May 2025

Gut bacteria and diet found to affect cancer treatment outcomes

A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.

22 May 2025

Reducing Polypharmacy with Innovative Drug Formulation Technologies

Discover how hot melt extrusion supports polypharmacy reduction and novel therapies for stroke and snakebite with expert insights.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 22 May 2025

Closed Loop Medicine appoints Kate Woolland as CEO

Closed Loop Medicine Ltd. (“CLM”), a leader in pharmaceutical precision dosing, today announced the appointment of Kate Woolland as Chief Executive Officer.

22 May 2025

Reduced monitoring after stroke found safe for low risk patients

Halving the number of times vital signs and neurological function are checked in low-risk patients after treatment for acute ischaemic stroke does not compromise care or recovery, according to new findings presented at the 11th European Stroke Organisation Conference in Helsinki, Finland.

22 May 2025

Vagus nerve stimulation shows unprecedented recovery rates in spinal cord injuries

In a new clinical study, researchers from the Texas Biomedical Device Center (TxBDC) at The University of Texas at Dallas demonstrated unprecedented rates of recovery for spinal cord injuries.

21 May 2025

Long-term antidepressant use linked to higher risk of withdrawal symptoms

People who have been taking antidepressants for more than two years are substantially more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new study led by UCL researchers.

21 May 2025

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy.

21 May 2025

New genetic mutation linked to increased prostate cancer risk in Ashkenazi Jewish men

Identifying and classifying gene mutations - which are the permanent changes in a person's DNA genetic code - are critical in better understanding, and with research, eventually treating or preventing, the diseases with which they are linked.

21 May 2025

Study explains why some AML patients do not respond to standard treatment

An international study led by the University of Colorado Cancer Center has uncovered why a widely used treatment for acute myeloid leukemia (AML) doesn't work for everyone.

21 May 2025

Blood filtration may offer new hope for removing microplastics from the body

Researchers report the first evidence that therapeutic apheresis, a blood-filtration technique, can remove microplastic- and nanoplastic-like particles from humans with ME/CFS. While promising, further studies are needed to quantify removal and assess clinical benefits.

21 May 2025

UArizona researchers uncover new way to ease postoperative pain in women

University of Arizona Health Sciences researchers identified a potential way to reduce female post-operative pain by inhibiting pituitary prolactin generated by pre-operative stress.

20 May 2025

Post-Intensive Care Syndrome patients experience long-term deficits in cognitive and physical function

More than half of ICU survivors may experience Post-Intensive Care Syndrome (PICS), which involves new or worsening physical, psychological, or cognitive impairments after a critical illness.

20 May 2025

Therapy News and Research

Confocal microscopy may help identify biomarkers for chemotherapy-induced neuropathy

Integrating phytomedicine and nanotechnology in managing COVID-19 related heart disease

Cutting back on sugary drinks may protect men’s fertility, review finds

Metabolite profiles in spinal fluid predict mortality in tuberculous meningitis

Guideline-directed medical therapy boosts survival in the oldest heart attack patients

Understanding how cholera bacteria resist phage predation

Meta analysis highlights prognostic role of circPVT1 in solid tumors

New AI blood test tracks pancreatic cancer treatment response

Gut bacteria and diet found to affect cancer treatment outcomes

Reducing Polypharmacy with Innovative Drug Formulation Technologies

Closed Loop Medicine appoints Kate Woolland as CEO

Reduced monitoring after stroke found safe for low risk patients

Vagus nerve stimulation shows unprecedented recovery rates in spinal cord injuries

Long-term antidepressant use linked to higher risk of withdrawal symptoms

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

New genetic mutation linked to increased prostate cancer risk in Ashkenazi Jewish men

Study explains why some AML patients do not respond to standard treatment

Blood filtration may offer new hope for removing microplastics from the body

UArizona researchers uncover new way to ease postoperative pain in women

Post-Intensive Care Syndrome patients experience long-term deficits in cognitive and physical function

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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