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Study could boost development of personalised medicine in cancer care and therapy

A team of scientists led by Associate Professor Zeng Qi from A*STAR's Institute of Molecular and Cell Biology have discovered a new biomarker which will help physicians predict how well cancer patients respond to cancer drugs. Having the means to identify patients who are most likely to benefit from currently available cancer drugs not only reduces substantially the healthcare cost for the patient, it could mean saving precious lives by getting the right drugs to the right patient at the onset of the treatment.

7 Aug 2013

New guidelines for treating mental health consequences of trauma and loss

WHO is releasing new clinical protocols and guidelines to health-care workers for treating the mental health consequences of trauma and loss.

7 Aug 2013

Viewpoints: Health law's marketing challenge; GOP not to blame for implementation challenges

More than half of working-class whites say [the federal health law] is a bad idea. Perhaps most stunningly, so do 48% of those currently without health insurance - the very people who stand to gain the most, in the form of help finding and paying for coverage. Meanwhile, by a 30-point margin, political independents think they will be worse off under the law.

7 Aug 2013

Findings may allow lower doses of chemotherapy, limit toxic side effects

In research recently published in Nature Structural & Molecular Biology, Alessandro Vindigni, Ph.D., associate professor of biochemistry and molecular biology at Saint Louis University, discovered how cancer cells respond to the damage caused by an important class of anti-cancer drugs, topoisomerase I inhibitors.

7 Aug 2013

Expansion of heroin, opioid medical treatment needed to reduce overdose deaths

A new report from Simon Fraser University researcher Bohdan Nosyk calls for the expansion of heroin and opioid medical treatment to stem the increase of overdose deaths.

7 Aug 2013

Scientists discover biomarker that helps physicians predict how well cancer patients respond to drugs

A team of scientists led by Associate Professor Zeng Qi from A*STAR's Institute of Molecular and Cell Biology (IMCB) have discovered a new biomarker which will help physicians predict how well cancer patients respond to cancer drugs.

7 Aug 2013

Prolonged exposure therapy does not increase drinking in PTSD and alcohol dependent patients

Contrary to past concerns, using prolonged exposure therapy to treat patients with post-traumatic stress disorder (PTSD) and comorbid alcohol dependence does not increase drinking or cravings, Penn Medicine psychiatrists report in the August 7 issue of JAMA, a theme issue on violence/human rights.

7 Aug 2013

Study finds cancer survivors do not always have best access to primary care

While cancer survivors require follow-up care to prevent a recurrence of their cancer and to watch for after effects of treatment, they also need the same preventive check-ups suggested for all people.

7 Aug 2013

Genetic variations in genes could put patients at risk for statin-associated muscle injury: Study

Statins, a class of drugs used to lower cholesterol, are among the best selling drugs in North America and around the world. However, statin myopathy, which results in muscle pain and weakness, is a common side effect affecting up to 10 percent of statin users. A recent study led by Dr. Richard Kim of the Lawson Health Research Institute, in collaboration with Dr. Robert Hegele of Robarts Research Institute, and researchers from Vanderbilt University, found that commonly occurring genetic variations in a person's genes could put them at risk for statin-associated muscle injury.

7 Aug 2013

UCLA researchers combine cellular and gene therapies to develop treatment for breast cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center have successfully combined cellular therapy and gene therapy in a mouse-model system to develop a viable treatment strategy for breast cancer that has spread to a patient's brain.

7 Aug 2013

Single antibiotic treatment safe and effective for children with invasive bloodstream infections

Children with invasive bloodstream infections treated with a single antibiotic are just as likely to overcome their infections as those who get two-drug therapy, but at half the risk of drug-induced kidney damage, according to results of a Johns Hopkins Children’s Center study.

6 Aug 2013

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Investigators have linked aluminum accumulation in the brain as a possible contributing factor to neurodegenerative disorders such as Alzheimer's disease. A new study published in Restorative Neurology and Neuroscience sheds light on the mechanism underlying aluminum-induced neuronal cell death and identifies necrostatin-1 as a substance which counteracts several of aluminum's neurotoxic effects.

6 Aug 2013

Regeneron, Bayer report positive results from Phase 3 VIVID-DME and VISTA-DME trials of EYLEA for DME

Regeneron Pharmaceuticals, Inc. and Bayer HealthCare today announced that in the Phase 3 VIVID-DME and VISTA-DME trials of EYLEA (aflibercept) Injection for the treatment of diabetic macular edema, EYLEA 2 milligrams (mg) dosed monthly and EYLEA 2 mg dosed every two months (after 5 initial monthly injections) achieved the primary endpoint of a significantly greater improvement in best-corrected visual acuity from baseline compared to laser photocoagulation at 52 weeks.

6 Aug 2013

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

A team of scientists, led by Napoleone Ferrara, MD, has shown for the first time that a signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy.

6 Aug 2013

Columbia researchers identify 18 new genes that drive glioblastoma multiforme

A team of researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center has identified 18 new genes responsible for driving glioblastoma multiforme, the most common-and most aggressive-form of brain cancer in adults. The study was published August 5, 2013, in Nature Genetics.

6 Aug 2013

Life Tech, Raintree Launch Oncology Testing, Patient Data Initiatives

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6 Aug 2013

BioLineRx reports positive results from pre-clinical trials with RHB-104 for treatment of thrombocytopenia

BioLineRx, a biopharmaceutical development company, announced today that BL-8040 has been shown in pre-clinical trials to be effective for the treatment of thrombocytopenia, or reduced platelet production.

5 Aug 2013

Study opens door to possible treatments for variety of mitochondrial diseases

By borrowing a tool from bacteria that infect plants, scientists have developed a new approach to eliminate mutated DNA inside mitochondria-the energy factories within cells. Doctors might someday use the approach to treat a variety of mitochondrial diseases, including the degenerative eye disease Leber hereditary optic neuropathy. The research, published online today in Nature Medicine, was funded by the National Eye Institute, a part of the National Institutes of Health.

5 Aug 2013

European authorisation of Aegerion Pharmaceuticals' Lojuxta brings hope for HoFH patients

Aegerion Pharmaceuticals, Inc., a biopharmaceutical company dedicated to the development and commercialisation of novel, life-altering therapies for patients with debilitating, often fatal, rare diseases, announced today that the European Commission has authorised Lojuxta (lomitapide) hard capsules as an adjunct to a low-fat diet and other lipid-lowering medicinal products with or without low density lipoprotein apheresis in adult patients with homozygous familial hypercholesterolaemia.

3 Aug 2013

Life Care’s thoughts on neck pain from cervical herniated disc

Thoughts on neck pain from a Cervical Herniated Disc from Life Care Solutions Group's Sacramento Injury Lawyer, Dr. Greg Vigna.

3 Aug 2013

Therapy News and Research

Study could boost development of personalised medicine in cancer care and therapy

New guidelines for treating mental health consequences of trauma and loss

Viewpoints: Health law's marketing challenge; GOP not to blame for implementation challenges

Findings may allow lower doses of chemotherapy, limit toxic side effects

Expansion of heroin, opioid medical treatment needed to reduce overdose deaths

Scientists discover biomarker that helps physicians predict how well cancer patients respond to drugs

Prolonged exposure therapy does not increase drinking in PTSD and alcohol dependent patients

Study finds cancer survivors do not always have best access to primary care

Genetic variations in genes could put patients at risk for statin-associated muscle injury: Study

UCLA researchers combine cellular and gene therapies to develop treatment for breast cancer

Single antibiotic treatment safe and effective for children with invasive bloodstream infections

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Regeneron, Bayer report positive results from Phase 3 VIVID-DME and VISTA-DME trials of EYLEA for DME

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

Columbia researchers identify 18 new genes that drive glioblastoma multiforme

Life Tech, Raintree Launch Oncology Testing, Patient Data Initiatives

BioLineRx reports positive results from pre-clinical trials with RHB-104 for treatment of thrombocytopenia

Study opens door to possible treatments for variety of mitochondrial diseases

European authorisation of Aegerion Pharmaceuticals' Lojuxta brings hope for HoFH patients

Life Care’s thoughts on neck pain from cervical herniated disc

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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