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Researchers discover drug that halts growth of brain tumor cells

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of - and ultimately left no detectable trace of - brain tumor cells taken from adult human patients.

24 Sep 2013

Researchers reveals key role for stem cells that promote inflammation in atherosclerosis

University at Buffalo translational researchers are developing a richer understanding of atherosclerosis in humans, revealing a key role for stem cells that promote inflammation.

24 Sep 2013

Mild COPD phenotype discovery offers treatment hope

Research indicates that smokers with and without mild chronic obstructive pulmonary disease can be classified into distinct phenotypes on the basis of computed tomography findings.

23 Sep 2013

European Commission and Japan approve once-daily dual bronchodilator Ultibro Breezhaler (QVA149) nearly simultaneously, for COPD patients

Novartis announced today that the European Commission approved once-daily Ultibro® Breezhaler® (indacaterol 85 mcg / glycopyrronium 43 mcg) as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD). In addition, the Japanese Ministry of Health, Labour and Welfare (MHLW) approved once-daily Ultibro® Inhalation Capsules (glycopyrronium 50 mcg / indacaterol 110 mcg), delivered through the Breezhaler® device, for relief of various symptoms due to airway obstruction in chronic obstructive pulmonary disease (COPD). Ultibro® Breezhaler® / Ultibro® Inhalation Capsules were developed under the name QVA149.

23 Sep 2013

Abbvie, Ablynx Ink Up To $840M RA, SLE Collaboration

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23 Sep 2013

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Janssen Biotech, Inc., announced today that the U.S. Food and Drug Administration (FDA) has approved STELARA® (ustekinumab) alone or in combination with methotrexate for the treatment of adult patients (18 years or older) with active psoriatic arthritis.

23 Sep 2013

Researchers lead two major trials to test potential treatments for asbestos-related cancer

University of Leicester researchers are leading two major trials into treatments for a type of cancer which affects those exposed to asbestos.

23 Sep 2013

Almirall and GKV-SV reach agreement on pricing of Sativex medicine in Germany

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23 Sep 2013

Older women with newly diagnosed breast cancer are more likely to experience functional disability

Many older women with newly diagnosed breast cancer have difficulty accomplishing daily tasks, and African-Americans seem to be disproportionately affected.

23 Sep 2013

Study explains why survival is low in peritoneal dialysis patients

Clinicians and scientists from Keele and Cardiff universities have published data from a landmark study that explains why survival in patients on peritoneal dialysis is low.

23 Sep 2013

Abbvie, Ablynx ink license agreement to develop anti-IL-6R Nanobody against inflammatory diseases

Ablynx and AbbVie today announced that they have entered into a global license agreement to develop and commercialize the anti-IL-6R Nanobody, ALX-0061, to treat inflammatory diseases.

23 Sep 2013

Researchers report encouraging results from T1DAL study on type 1 diabetes

Encouraging results from the T1DAL study (Targeting effector memory T cells with alefacept in new onset type 1 diabetes), led by Mark R. Rigby MD, PhD from Indiana University and Riley Hospital for Children in Indianapolis and sponsored by the Immune Tolerance Network (ITN) with additional support from JDRF, are published today in The Lancet Diabetes & Endocrinology.

23 Sep 2013

Evidence shows that fear memories can be reduced during sleep

A fear memory was reduced in people by exposing them to the memory over and over again while they slept. It's the first time that emotional memory has been manipulated in humans during sleep, report Northwestern Medicine- scientists.

23 Sep 2013

Accuray to present advanced radiation oncology treatment solutions at 2013 ASTRO

Accuray Incorporated (Nasdaq: ARAY) announced today its momentum in gaining adoption for both the new CyberKnife® M6™ Series and TomoTherapy® H™ Series Systems at the 55th Annual American Society for Radiation Oncology (ASTRO) Meeting taking place at the Georgia World Congress Center in Atlanta.

23 Sep 2013

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

The Cardiovascular Research Foundation (CRF) has announced the late breaking trials and first report investigations that will be presented at next month's Transcatheter Cardiovascular Therapeutics (TCT) 2013 scientific symposium.

21 Sep 2013

State highlights: 850K Texas kids lack health coverage; Calif. counties brace for health department cuts; autism coverage change hailed in Calif.

Texas continued to have the highest rate of people without health insurance in 2012 at 24.6 percent, or more than 6 million residents, according to the Current Population Survey estimates released by the U.S. Census Bureau this week.

21 Sep 2013

Phase III EINSTEIN trial program: XARELTO reduces risk of DVT and PE

Janssen Pharmaceuticals, Inc. announced today a newly published, pooled analysis of the Phase III EINSTEIN trial program, showing XARELTO (rivaroxaban) is as effective as the standard of care in reducing the risk of deep vein thrombosis and pulmonary embolism in people with symptomatic DVT or PE, while reducing the incidence of major bleeding by 46 percent.

21 Sep 2013

More AIDS-defining illnesses and severe side effects occur with appropriate comparator therapy

The drug combination of elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil (elvitegravir fixed combination, trade name: Stribild) has been approved in Germany since May 2013 for the treatment of adults infected with human immunodeficiency virus type 1 (HIV-1).

21 Sep 2013

Higher calorie diets produce twice rate of weight gain for adolescents hospitalized with anorexia

Higher calorie diets produce twice the rate of weight gain compared to the lower calorie diets that currently are recommended for adolescents hospitalized with anorexia nervosa, according to a study by researchers at UCSF Benioff Children-s Hospital.

21 Sep 2013

Digoxin linked with higher rate of death among adults with diagnosed systolic heart failure

Digoxin, a drug commonly used to treat heart conditions, was associated with a 72 percent higher rate of death among adults with newly diagnosed systolic heart failure, according to a Kaiser Permanente study that appears in the current online issue of Circulation: Cardiovascular Quality and Outcomes.

21 Sep 2013

Therapy News and Research

Researchers discover drug that halts growth of brain tumor cells

Researchers reveals key role for stem cells that promote inflammation in atherosclerosis

Mild COPD phenotype discovery offers treatment hope

European Commission and Japan approve once-daily dual bronchodilator Ultibro Breezhaler (QVA149) nearly simultaneously, for COPD patients

Abbvie, Ablynx Ink Up To $840M RA, SLE Collaboration

FDA approves STELARA (Ustekinumab) for treatment of active psoriatic arthritis

Researchers lead two major trials to test potential treatments for asbestos-related cancer

Almirall and GKV-SV reach agreement on pricing of Sativex medicine in Germany

Older women with newly diagnosed breast cancer are more likely to experience functional disability

Study explains why survival is low in peritoneal dialysis patients

Abbvie, Ablynx ink license agreement to develop anti-IL-6R Nanobody against inflammatory diseases

Researchers report encouraging results from T1DAL study on type 1 diabetes

Evidence shows that fear memories can be reduced during sleep

Accuray to present advanced radiation oncology treatment solutions at 2013 ASTRO

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

State highlights: 850K Texas kids lack health coverage; Calif. counties brace for health department cuts; autism coverage change hailed in Calif.

Phase III EINSTEIN trial program: XARELTO reduces risk of DVT and PE

More AIDS-defining illnesses and severe side effects occur with appropriate comparator therapy

Higher calorie diets produce twice rate of weight gain for adolescents hospitalized with anorexia

Digoxin linked with higher rate of death among adults with diagnosed systolic heart failure

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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