Protein C News and Research

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Researchers identify factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

5 Nov 2013

Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

Leicester scientists have mapped the "bouquet-like" structure of a key part of the body's immune system responsible for neutralising bacteria and viruses.

5 Nov 2013

LMU researchers identify a factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

4 Nov 2013

GeNeuro's GNbAC1 antibody demonstrates safety profile in Phase 2a study for MS

GeNeuro announced today that its GNbAC1 humanized monoclonal antibody was found to have a very good safety profile when administered to patients with relapsing and progressive forms of Multiple Sclerosis as part of a Phase 2a study.

4 Nov 2013

Research findings offer new therapeutic paradigm for periodontal disease

The red, swollen and painful gums and bone destruction of periodontal disease could be effectively treated by beckoning the right kind of immune system cells to the inflamed tissues, according to a new animal study conducted by researchers at the University of Pittsburgh.

4 Nov 2013

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

Women vaccinated with one dose of a human papillomavirus (HPV) vaccine had antibodies against the viruses that remained stable in their blood for four years, suggesting that a single dose of vaccine may be sufficient to generate long-term immune responses and protection against new HPV infections, and ultimately cervical cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

4 Nov 2013

McMaster University researchers discover how metformin drug works on fat in the liver

About 120 million people around the world with Type 2 diabetes - and two million in Canada - take the drug metformin to control their disease.

4 Nov 2013

Experimental drug effective in treating patients with non-small cell lung cancer

An experimental cancer drug that has shown promise in the treatment of melanoma has also shown early potential as an effective treatment for patients with non-small cell lung cancer, the leading cause of cancer death among men and women worldwide.

4 Nov 2013

Discovery may lead to curing of Alzheimer's and Parkinson's disease via photo therapy

Researchers at Chalmers University of Technology in Sweden, together with researchers at the Polish Wroclaw University of Technology, have made a discovery that may lead to the curing of diseases such as Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease (the so called mad cow disease) through photo therapy.

3 Nov 2013

Oncology drug development services: an interview with Dr. Jean-Pierre Wery, President of Crown Bioscience, Inc.

Crown serves pharmaceutical companies and biotech companies. We have two areas of focus: oncology and metabolic diseases. In the oncology space we focus on pre-clinical services. Essentially, we have all the tools to help our customers move from target discovery, target validation, to a clinical candidate.

31 Oct 2013

Scientists uncover new mechanism through which gene expression is regulated

A new study by Weill Cornell Medical College scientists reveals a mechanism through which the expression of genes is controlled -- a finding that highlights genetic mutations that can impair the timing of gene expression.

31 Oct 2013

Prana's PBT2 effective in reversing memory, learning losses associated with aging process

Prana Biotechnology, a leading global developer of first-in-class treatments for neurodegenerative disease, has today announced the publication of an article in the peer reviewed Aging Cell showing the effects of PBT2 on neurogenesis and in reversing the memory and learning losses associated with the aging process, in normal (ie non transgenic) old mice.

31 Oct 2013

Kamada announces new data from Glassia Phase I/II study in pediatric patients with type 1 diabetes

Kamada Ltd., a plasma-derived protein therapeutics company focused on orphan indications, today reported preliminary data from the Company's ongoing extension study of a Phase I/II clinical trial with its lead product Glassia® to treat pediatric patients with a recently diagnosed type 1 diabetes (T1D).

31 Oct 2013

Meal replacements and high protein diet can help weight loss maintenance

New research shows that there are several effective strategies available to people wanting to avoid regaining weight after a successful diet. Anti-obesity drugs, meal replacements and a high protein diet can help weight loss maintenance, according to a meta-analysis published in the scientific periodical The American Journal of Clinical Nutrition.

31 Oct 2013

"Good" cholesterol improves blood glucose levels, say scientists

High density lipoprotein cholesterol (HDL), the so-called "good" cholesterol improves blood glucose levels by enhancing skeletal muscle function and reducing adiposity, scientists of the Helmholtz Zentrum München report in the current issue of the renown American Heart Association Journal ‚Circulation'.

31 Oct 2013

S14G-humanin: New effective treatment for Alzheimer's disease

Humanin is a potential therapeutic agent for Alzheimer's disease, and its derivative, S14G-humanin, is 1 000-fold stronger in its neuroprotective effect against Alzheimer's disease-relevant insults. Al-though effective, the detailed molecular mechanism through which S14G-humanin exerts its effects remains unclear.

31 Oct 2013

Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

Experiments by scientists at Johns Hopkins and in Boston have unraveled two biological mechanisms as the major cause of protein citrullination in rheumatoid arthritis. Protein citrullination is suspected of sparking the immune system and driving the cascade of events leading to the disease.

31 Oct 2013

Reduced SMG1 protein expression may contribute to neurological disorders

The absence of a protein called SMG1 could be a contributing factor in the development of Parkinson's disease and other related neurological disorders, according to a study led by the Translational Genomics Research Institute.

31 Oct 2013

EZH2 protein may aid prognostication in resected NSCLC

A protein called “enhancer of zeste homolog-2” is frequently expressed in non-small-cell lung cancer and may have prognostic value following surgical resection, US researchers believe.

30 Oct 2013

Promising melanoma drug demonstrates potential for non-small cell lung cancer treatment

An experimental new cancer drug called MK-3475, which has shown dramatic promise for treating melanoma is also showing early potential as an effective treatment for patients with non-small cell lung cancer, the leading cause of cancer death of men and women worldwide.

30 Oct 2013

Protein C News and Research

Researchers identify factor that promotes metastasis of colon tumors

Scientists map structure of key part of immune system responsible for neutralizing bacteria, viruses

LMU researchers identify a factor that promotes metastasis of colon tumors

GeNeuro's GNbAC1 antibody demonstrates safety profile in Phase 2a study for MS

Research findings offer new therapeutic paradigm for periodontal disease

Study: Single dose of HPV vaccine may be sufficient to protect cervical cancer

McMaster University researchers discover how metformin drug works on fat in the liver

Experimental drug effective in treating patients with non-small cell lung cancer

Discovery may lead to curing of Alzheimer's and Parkinson's disease via photo therapy

Oncology drug development services: an interview with Dr. Jean-Pierre Wery, President of Crown Bioscience, Inc.

Scientists uncover new mechanism through which gene expression is regulated

Prana's PBT2 effective in reversing memory, learning losses associated with aging process

Kamada announces new data from Glassia Phase I/II study in pediatric patients with type 1 diabetes

Meal replacements and high protein diet can help weight loss maintenance

"Good" cholesterol improves blood glucose levels, say scientists

S14G-humanin: New effective treatment for Alzheimer's disease

Scientists unravel the major cause of protein citrullination in rheumatoid arthritis

Reduced SMG1 protein expression may contribute to neurological disorders

EZH2 protein may aid prognostication in resected NSCLC

Promising melanoma drug demonstrates potential for non-small cell lung cancer treatment

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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