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Parenting stress among caregivers of children with chronic illness: A systematic review

The extra demands on parents of chronically ill children cause stress that affects the whole family, according to a systematic review conducted by Case Western Reserve University researchers that also explored what factors in the child's care most contribute to the added strain.

19 Sep 2013

Overactivity of EGFR protein leads to heightened cancer growth and chemotherapy resistance

Overactivity of a protein that normally cues cells to divide sabotages the body-s natural cellular recycling process, leading to heightened cancer growth and chemotherapy resistance, UT Southwestern Medical Center researchers have found.

19 Sep 2013

Research opens up longer therapy window for children with neurodevelopmental disorders

The development of fine motor control-the ability to use your fingertips to manipulate objects-takes longer than previously believed, and isn't entirely the result of brain development, according to a pair of complementary studies.

19 Sep 2013

Study: Neurocognitive impairment is one of common side effects of HIV and AIDS

One of the common side effects of HIV and AIDS is neurocognitive impairments - changes in how fast a person can process information, pay attention, multi-task and remember things - yet there are no adequate tests to screen patients for these problems, according to a new study out of St. Michael's Hospital.

19 Sep 2013

New information about how estrogens regulate memory formation

The loss of estrogens at menopause increases a woman's risk of dementia and Alzheimer's disease, yet hormone replacement therapy can cause harmful side effects.

19 Sep 2013

New gonorrhea treatment eliminates gonococcal infection from female mice

A new gonorrhea treatment, based on an anti-cancer therapy developed by a Buffalo startup company, has successfully eliminated gonococcal infection from female mice and prevented reinfection, according to research published today by University at Buffalo scientists in the Journal of Infectious Diseases.

19 Sep 2013

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Over the last decade researchers have amassed increasing evidence that relatively low levels of a protein called sex hormone binding globulin (SHBG) can indicate an elevated risk of type 2 diabetes and metabolic syndrome years in advance.

19 Sep 2013

Wayne State University initiates groundbreaking multiple sclerosis study

A groundbreaking study in multiple sclerosis focusing on "remyelination in the brain" has been initiated by Omar Khan, M.D., professor and chair of neurology at the Wayne State University School of Medicine.

19 Sep 2013

Researchers discover why multiple myeloma recurs after initially effective treatment

Researchers have discovered why multiple myeloma, a difficult to cure cancer of the bone marrow, frequently recurs after an initially effective treatment that can keep the disease at bay for up to several years.

19 Sep 2013

Guidance for medication in bipolar depression published

Solid evidence to guide the use of antidepressants in patients with bipolar disorder is “remarkably limited,” says the International Society for Bipolar Disorders Task Force.

18 Sep 2013

GSK Returns Vercirnon Rights To Chemocentryx After Phase III Flop

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18 Sep 2013

Gout: An Interview with Dr. Lawrence Edwards, Chairman and CEO of GUAES

Gout is the most common form of inflammatory arthritis that affects adults. It's a disease caused by the presence of uric acid crystals in and around the joints. It's a disease that's becoming more and more common. It probably has doubled in its prevalence worldwide over the past twenty to thirty years.

18 Sep 2013

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Results of a Pfizer-commissioned study published this month in Annals of Internal Medicine reveal that smokers with a past or present diagnosis of major depressive disorder (MDD)* taking varenicline had a significantly higher likelihood of quitting smoking (after 12 weeks and at 52 weeks) than those who were given a placebo.

18 Sep 2013

UAB paper suggests that physical activity, exercise important for healthy aging

A clinical review from geriatricians at the University of Alabama at Birmingham suggests that mobility limitations are a litmus test for healthy aging and urges primary care physicians to take a more aggressive role in ascertaining the mobility of their older patients.

18 Sep 2013

AAPM commends FDA’s move to introduce labeling changes on ER/LA opioids

The physicians of the American Academy of Pain Medicine (AAPM) hailed long-awaited labeling changes and other steps taken by the U.S. Food and Drug Administration (FDA) last week to enhance safety in the prescribing of extended-release and long-acting (ER/LA) opioids.

18 Sep 2013

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

Boehringer Ingelheim and Eli Lilly and Company today announced they will feature five oral and 12 poster presentations for linagliptin and the investigational compound empagliflozin* at the 49th Annual Meeting of the European Association for the Study of Diabetes (EASD) which will take place in Barcelona, from 23 – 27 September. The presentations will add to the already existing body of data on safety and efficacy of these two compounds.

18 Sep 2013

GW Pharmaceuticals starts GWP42006 Phase 1 clinical trial for epilepsy treatment

GW Pharmaceuticals plc announced today it has commenced a Phase 1 clinical trial of product candidate GWP42006 for the treatment of epilepsy.

18 Sep 2013

Study proves advantages of immediate surgery for patients with acute cholecystitis

Should surgery be performed immediately, or is it better to first administer antibiotics and then perform surgery? A study led by Heidelberg University Hospital Department of Surgery has demonstrated that patients suffering from acute cholecystitis should be operated on immediately. There are no advantages to delaying surgery until antibiotic therapy has been administered for several weeks. After undergoing surgery performed within 24 hours of diagnosis, the patients have fewer complications, are back on their feet earlier, and can leave the hospital more quickly.

18 Sep 2013

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

Researchers from the University of Chicago have been awarded a five-year, $1.5 million grant from the National Institutes of Health to develop stimulated dendritic cell-derived exosomes that show remarkable promise as a treatment for multiple sclerosis and other neurological diseases involving loss of myelin, the insulation around nerve fibers.

18 Sep 2013

SignaBlok's novel peptide inhibitor of TREM-1 suppresses cancer progression

SignaBlok, Inc., a Massachusetts-based biopharmaceutical company, today announced the successful in vivo proof of concept data that demonstrate that the company's novel mechanism-based, first-in-class peptide inhibitor of TREM-1 effectively suppresses cancer progression in mouse models of lung cancer and dramatically improves survival in septic mice.

18 Sep 2013

Therapy News and Research

Parenting stress among caregivers of children with chronic illness: A systematic review

Overactivity of EGFR protein leads to heightened cancer growth and chemotherapy resistance

Research opens up longer therapy window for children with neurodevelopmental disorders

Study: Neurocognitive impairment is one of common side effects of HIV and AIDS

New information about how estrogens regulate memory formation

New gonorrhea treatment eliminates gonococcal infection from female mice

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Wayne State University initiates groundbreaking multiple sclerosis study

Researchers discover why multiple myeloma recurs after initially effective treatment

Guidance for medication in bipolar depression published

GSK Returns Vercirnon Rights To Chemocentryx After Phase III Flop

Gout: An Interview with Dr. Lawrence Edwards, Chairman and CEO of GUAES

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

UAB paper suggests that physical activity, exercise important for healthy aging

AAPM commends FDA’s move to introduce labeling changes on ER/LA opioids

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

GW Pharmaceuticals starts GWP42006 Phase 1 clinical trial for epilepsy treatment

Study proves advantages of immediate surgery for patients with acute cholecystitis

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

SignaBlok's novel peptide inhibitor of TREM-1 suppresses cancer progression

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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