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Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Mature cells also play role in initiating cancer, study suggests

Rapidly dividing, yet aberrant stem cells are a major source of cancer. But a new study suggests that mature cells also play a key role in initiating cancer - a finding that could upend the way scientists think about the origin of the disease.

18 Dec 2017

New review provides guidance to doctors who may treat infants with ‘bubble boy disease’

A new review provides guidance on a deadly, but rare, disease that is potentially curable if identified early. Severe combined immunodeficiency disease (SCID), known as the "bubble boy disease" in the 1970s, is treatable with a stem cell transplant, gene therapy and other treatments if identified at birth or soon after.

18 Dec 2017

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Cell phones should be kept away from the body warn California health officials

Last week the California Department of Public Health (CDPH) issued a guideline that would help the public reduce the radiation exposure from cell phones. The guidelines clearly state that cell phones need to be kept away from the body.

18 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Study reveals biology behind why muscle stem cells respond differently to aging or injury

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute describes the biology behind why muscle stem cells respond differently to aging or injury.

15 Dec 2017

HKBU experts develop new generation of smart anti-cancer drug molecules

The toxic nature of chemotherapy poses a great challenge to clinical treatment of cancer. A team of scholars from the School of Chinese Medicine of Hong Kong Baptist University devoted their efforts to the development of a new generation of smart anti-cancer drug molecules.

15 Dec 2017

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, and how to improve the treatment of illness in the future.

15 Dec 2017

Scientists use nanoparticles to fight Mucoviscidosis

Scientists of the Friedrich Schiller University Jena, Germany succeeded in developing an efficient method to treat Mucoviscidosis. Crucial are nanoparticles that transport the antibiotics more efficiently to their destination.

15 Dec 2017

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level.

15 Dec 2017

Scientists use AI-enhanced microscope system to quickly, accurately identify bacteria

Microscopes enhanced with artificial intelligence could help clinical microbiologists diagnose potentially deadly blood infections and improve patients' odds of survival, according to microbiologists at Beth Israel Deaconess Medical Center

15 Dec 2017

Researchers uncover THOR gene involved in cancer development

It turns out Thor, the Norse god of thunder and the Marvel superhero, has special powers when it comes to cancer too.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Researchers have glimpsed how the toxic protein clusters that are associated with Parkinson's Disease disrupt the membranes of healthy brain cells, creating defects in the cell walls and eventually causing a series of events that induce neuronal death.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

Extracellular vesicles can be used to effectively delay progression of kidney damage

Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage in mice with a type of chronic kidney disease.

15 Dec 2017

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Researchers at Kanazawa University report in EMBO Reports, 7 December 2017, new molecular mechanisms regulating cellular fate of squamous cell carcinomas.

15 Dec 2017

Scientists create atomic scale map that tracks how brain signals connect to neurons

Scientists at Johns Hopkins have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to a neuron in the brain. The findings, say the scientists, shed light on the dynamic physics of the chemical's pathway, as well as the speed of nerve cell communications.

15 Dec 2017

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

B Cell News and Research

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Mature cells also play role in initiating cancer, study suggests

New review provides guidance to doctors who may treat infants with ‘bubble boy disease’

Excessive copper in diabetes impedes ability to make new blood vessels

Cell phones should be kept away from the body warn California health officials

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

Study reveals biology behind why muscle stem cells respond differently to aging or injury

HKBU experts develop new generation of smart anti-cancer drug molecules

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

Scientists use nanoparticles to fight Mucoviscidosis

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

Scientists use AI-enhanced microscope system to quickly, accurately identify bacteria

Researchers uncover THOR gene involved in cancer development

Researchers examine human mutations' impact on therapeutic effect of medicine

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Extracellular vesicles can be used to effectively delay progression of kidney damage

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Scientists create atomic scale map that tracks how brain signals connect to neurons

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

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