Therapy News and Research

RSS

UPCI research could provide roadmap for developing personalized therapies for breast cancer

More than 230,000 women will be diagnosed with breast cancer in the U.S. this year, a diagnosis that comes with treatment choices that can be overwhelming to patients and complex to their doctors. But what if there was only one treatment for your breast cancer? And what if it was based on your genetics and specific cancer type in the hope of maximizing its effectiveness?

24 Jul 2013

Study: Breathing oxygen during radiation therapy can delay tumor growth

A multidisciplinary team at UT Southwestern Medical Center has found that measuring the oxygenation of tumors can be a valuable tool in guiding radiation therapy, opening the door for personalized therapies that keep tumors in check with oxygen enhancement.

24 Jul 2013

Study reveals fungus coating on stored food may worsen AIDS epidemic

A type of fungus coating much of the stored corn, wheat, rice and nuts in developing countries may be quietly worsening the AIDS epidemic, according to a paper published today in the World Mycotoxin Journal.

24 Jul 2013

Research team receives NCI grant to develop precision therapies that kill cancer cells

A research team headed by Fred Hutchinson Cancer Research Center scientists Christopher Kemp, Ph.D., and Carla Grandori, M.D., Ph.D., has received a $4 million grant from the National Cancer Institute to develop precision therapies that selectively kill cancer cells while sparing normal, healthy tissue.

24 Jul 2013

Four research teams receive NIH grants to explore use of genome sequencing in medical care

The National Institutes of Health has awarded four grants for up to four years to multidisciplinary research teams to explore the use of genome sequencing in medical care. The awards total approximately $6.7 million in the first year and, if funding remains available, approximately $27 million in total.

24 Jul 2013

Genentech announces that Phase III CLL11 study meets primary endpoint

Genentech, a member of the Roche Group, today announced positive results from the Phase III CLL11 study. At a pre-planned interim analysis, an independent data monitoring committee determined that the study met its primary endpoint showing that GA101 plus chlorambucil helped people live significantly longer without their disease worsening (progression-free survival; PFS) compared to Rituxan (rituximab) plus chlorambucil.

24 Jul 2013

Digital versions of standard molecular biology tool to detect common tumor-associated mutation in CSF

Massachusetts General Hospital (MGH) researchers and their colleagues have used digital versions of a standard molecular biology tool to detect a common tumor-associated mutation in the cerebrospinal fluid (CSF) of patients with brain tumors. In their report being published in the open-access journal Molecular Therapy - Nucleic Acids, the investigators describe using advanced forms of the gene-amplification technology polymerase chain reaction (PCR) to analyze bits of RNA carried in membrane-covered sacs called extracellular vesicles for the presence of a tumor-associated mutation in a gene called IDH1.

24 Jul 2013

New treatment guidelines on diagnosis and management of achalasia

New treatment guidelines on the diagnosis and management of achalasia, a primary motor disorder of the esophagus, appear in the August issue of The American Journal of Gastroenterology.

24 Jul 2013

BD Saf-T-Intima Safety Integrated IV Catheter System gets European approval for subcutaneous infusion therapy

BD (Becton, Dickinson and Company), a leading global medical technology company, announces the approval of the BD Saf-T-Intima Safety Integrated IV Catheter System for use in subcutaneous infusion therapies in Europe.

From BD (Becton, Dickinson and Company) 23 Jul 2013

Array BioPharma announces positive results from ARRY-502 Phase 2 trial for allergic asthma

Array BioPharma Inc. today announced positive results from a placebo-controlled, randomized, double‑blind Phase 2 trial in mild to moderate persistent allergic asthma for ARRY-502, an oral CRTh2 antagonist.

23 Jul 2013

Potential breakthrough to help prevent diabetes

The resistance to insulin seen in type 2 diabetics is caused partly by the lack of a protein that has not previously been associated with diabetes. This breakthrough could potentially help to prevent diabetes.

23 Jul 2013

Study documents reversal of established medical practices in last decade

While there is an expectation that newer medical practices improve the standard of care, the history of medicine reveals many instances in which this has not been the case. Reversal of established medical practice occurs when new studies contradict current practice. Reporters may remember hormone replacement therapy as an example of medical reversal. A new analysis published in Mayo Clinic Proceedings documents 146 contemporary medical practices that have subsequently been reversed.

23 Jul 2013

Researchers develop microbial washing technique to decontaminate fetal tissues

The use of central nervous system fetal tissues derived from routine elective abortions to provide stem cells for transplantation procedures aimed at restoring damage done by neurodegenerative diseases is an established therapy.

23 Jul 2013

Melatonin pre-treatment greatly increases cell survival, say researchers

When melatonin, a hormone secreted by the pineal gland, was used as a pre-treatment for mesenchymal stem cells prior to their transplantation into the brains of laboratory animals to repair damage from stroke, researchers in China found that the stem cells survived longer after transplantation. Previous studies had shown that 80 percent of transplanted MSCs died within 72 hours of transplantation.

23 Jul 2013

Scientists identify circuitry in brain that drives compulsive drinking in rats

A research team led by scientists from the Ernest Gallo Clinic and Research Center at the University of California, San Francisco has identified circuitry in the brain that drives compulsive drinking in rats, and likely plays a similar role in humans.

23 Jul 2013

NF-κB protein complex may boost immune system to eliminate cancerous cells

Researchers at Moffitt Cancer Center and Tianjin Medical University Cancer Institute and Hospital in China have discovered a gene expression signature that may lead to new immune therapies for lung cancer patients.

23 Jul 2013

Imprimis to begin IRB-approved Impracor Phase III trial for acute pain associated with OA of the knee

Imprimis Pharmaceuticals, Inc., which is focused on the commercialization of compounded drug formulations utilizing the FDA 505(b)(2) development pathway, today announced it has received IRB approval for its Phase III clinical trial protocol of its lead product candidate, Impracor.

23 Jul 2013

New finding provides fresh hope for women with oestrogen receptor positive breast cancer

A new finding provides fresh hope for the millions of women worldwide with oestrogen receptor positive breast cancer. Australian scientists have shown that a specific change, which occurs when tumours become resistant to anti-oestrogen therapy, might make the cancers susceptible to treatment with chemotherapy drugs.

23 Jul 2013

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

P53 is a tumor suppressor gene. The gene encodes for a protein that monitors the state of the cell. If something goes wrong, it stops the cell from dividing or causes the cell to commit suicide. I call it the “guardian of the genome” as it is the molecule that seems to keep cells normal. It is one of our big defenses against cancer.

22 Jul 2013

Great Lakes NeuroTechnologies receives patent for Parkinson’s disease monitoring technology

Great Lakes NeuroTechnologies announced today they have received allowance of claims from the U.S. Patent Office for an application covering their system and method of stimulating the brain during sleep to treat movement disorder symptoms.

22 Jul 2013

Therapy News and Research

UPCI research could provide roadmap for developing personalized therapies for breast cancer

Study: Breathing oxygen during radiation therapy can delay tumor growth

Study reveals fungus coating on stored food may worsen AIDS epidemic

Research team receives NCI grant to develop precision therapies that kill cancer cells

Four research teams receive NIH grants to explore use of genome sequencing in medical care

Genentech announces that Phase III CLL11 study meets primary endpoint

Digital versions of standard molecular biology tool to detect common tumor-associated mutation in CSF

New treatment guidelines on diagnosis and management of achalasia

BD Saf-T-Intima Safety Integrated IV Catheter System gets European approval for subcutaneous infusion therapy

Array BioPharma announces positive results from ARRY-502 Phase 2 trial for allergic asthma

Potential breakthrough to help prevent diabetes

Study documents reversal of established medical practices in last decade

Researchers develop microbial washing technique to decontaminate fetal tissues

Melatonin pre-treatment greatly increases cell survival, say researchers

Scientists identify circuitry in brain that drives compulsive drinking in rats

NF-κB protein complex may boost immune system to eliminate cancerous cells

Imprimis to begin IRB-approved Impracor Phase III trial for acute pain associated with OA of the knee

New finding provides fresh hope for women with oestrogen receptor positive breast cancer

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

Great Lakes NeuroTechnologies receives patent for Parkinson’s disease monitoring technology

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News