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Rensselaer professors team up to develop innovative biomanufacturing technology

Two chemical engineering professors at Rensselaer Polytechnic Institute are contributing to a collaboration among academia, industry, and the federal government to develop a method for rapidly manufacturing biologic drugs.

4 Dec 2013

Scientists receive $12.5M NIH grant to continue research on targeted therapies for melanoma

Despite recent advances in therapy, melanoma remains the deadliest, most aggressive form of skin cancer as incidence rates continue to climb. Now, a team of melanoma scientists from The Wistar Institute and the University of Pennsylvania received a $12.5 M, five-year program project grant (P01) from the National Institutes of Health to continue trailblazing research on targeted therapies in melanoma.

4 Dec 2013

Gladstone scientist devise new molecular sensor that can detect MS at earliest stages

For some, the disease multiple sclerosis attacks its victims slowly and progressively over a period of many years. For others, it strikes without warning in fits and starts. But all patients share one thing in common: the disease had long been present in their nervous systems, hiding under the radar from even the most sophisticated detection methods. But now, scientists at the Gladstone Institutes have devised a new molecular sensor that can detect MS at its earliest stages-even before the onset of physical signs.

3 Dec 2013

LabCorp's HCV GenoSure NS3/4 test now available for Q80K polymorphism screening

Laboratory Corporation of America Holdings announced today the immediate availability of an enhanced version of its HCV GenoSure NS3/4, a drug resistance test that screens for the Q80K polymorphism. Q80K is a naturally occurring polymorphism that develops in certain strains of HCV, making the virus less susceptible to Janssen Therapeutics' OLYSIO (simeprevir), which was recently approved by the U.S. Food and Drug Administration for the treatment of certain adult patients diagnosed with genotype 1chronic hepatitis C.

3 Dec 2013

Researchers find way to replace Paneth cells with two small molecules that maintain stem cells

Researchers at MIT and Brigham and Women's Hospital have shown that they can grow unlimited quantities of intestinal stem cells, then stimulate them to develop into nearly pure populations of different types of mature intestinal cells. Using these cells, scientists could develop and test new drugs to treat diseases such as ulcerative colitis.

3 Dec 2013

Biotest, EpiVax partner to develop novel, non-immunogenic Factor VIII for hemophilia treatment

Biotest AG, Dreieich, Germany and EpiVax, Inc., Providence, Rhode Island, USA are pleased to announce a new Collaborative Research Agreement. With this collaboration a novel, non-immunogenic Factor VIII should be developed.

3 Dec 2013

CUMC researchers make new breakthrough in regenerative medicine

As fast-growing biotech company Rainbow Coral Corp. works to deliver new cutting-edge treatments in the field of regenerative medicine, a major new breakthrough could soon lead to growing new lungs for patients in a laboratory.

3 Dec 2013

EU pledges over $500 million to fight AIDS, TB and malaria

The European Union today announced at the Global Fund's Replenishment Conference in Washington, DC, new support of over US $500 million to fight AIDS, tuberculosis and malaria for the 2014-2016 period. The conference takes place just one day after World AIDS Day.

3 Dec 2013

Microneedle technique may provide a painless way to deliver drugs, vaccines

Microneedles on a sticking-plaster-like patch may be the painless and safe way doctors will test for drugs and some infections in the future, thanks to work supported by the Engineering and Physical Sciences Research Council (EPSRC).

3 Dec 2013

Researchers offer promise of strategy for curing HIV infection

Researchers have used radioimmunotherapy (RIT) to destroy remaining human immunodeficiency virus (HIV)-infected cells in the blood samples of patients treated with antiretroviral therapy, offering the promise of a strategy for curing HIV infection. Results of the study were presented today at the annual meeting of the Radiological Society of North America (RSNA).

3 Dec 2013

Scientists figure out how transporters work

Researchers have tried for decades to understand the undulations and gyrations that allow transport proteins to shuttle molecules from one side of a cell membrane to the other.

3 Dec 2013

New catalog brings interactions between pharmacological molecules and proteins

The three-dimensional structures of proteins determine how, when and where they bind to drugs and other compounds. In 2012 alone, thousands of structures like this were resolved.

3 Dec 2013

Research proves effectiveness of vaccine against leishmaniasis

The disease is considered endemic in the south states of Mexico. A research executed in the Autonomous University of Yucatan (UADY) has successfully proved, in test animals, the effectiveness of a vaccine that immunizes the organism against leishmaniasis, an ailment transmitted through insects very similar to mosquitos and mainly presents symptoms in the skin, liver or spleen.

3 Dec 2013

New robot to guide surgery, needle insertion, catheters and stents

This robot has a hybrid powerstrain structure which will allow a precise, repetitive, planned and controlled insertion enhancing the current procedures used so far. In addition, it has a lower cost and it requires a brief period of learning.

3 Dec 2013

Scientists investigate factors that influence choice of abused drugs

Prescription opioid abuse has reached epidemic levels in the past 15 years. Scientists investigating why people favor one drug over another have found that oxycodone and hydrocodone are the drugs of choice for 75% of opioid-dependent individuals.

3 Dec 2013

Researchers use hyperthermia to treat patients with malignant glioma

Malignant glioma is very sensitive to heat. Prof. Yunlong Ge and team from the Second Affiliated Hospital of Harbin Medical University, China used a brain tumor hyperthermia apparatus to treat malignant glioma patients, and achieved good therapeutic efficacy.

3 Dec 2013

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently published an article stressing the importance of standardizing drug screening studies in the prestigious scientific journal Nature. The study supports the need for further development and standardization to improve the reproducibility of drug screening studies, as they are important in identifying new therapeutic agents and their potential combinations with existing drugs.

3 Dec 2013

New finding links obesity and high-fat, high-sugar diets with changes in inflammatory status

Scientists have moved a step closer to an "obesity drug" that may block the effects of diets high in sugar and fats. In a new research report published in the December 2013 issue of The FASEB Journal, scientists show that there is an abnormal amount of an inflammatory protein called PAR2 in the abdominal fat tissue of overweight and obese humans and rats.

3 Dec 2013

Oxygen levels play critical role in determining effectiveness of anti-inflammatory drugs

A new research discovery published in the December 2013 issue of the Journal of Leukocyte Biology yields an important clue toward helping curb runaway inflammation. Oxygen levels play a critical role in determining the severity of the inflammatory response and ultimately the effectiveness of anti-inflammatory drugs.

3 Dec 2013

Scientists explain new family of proteins that appear to play key role in cancer

Scientists have described a new family of proteins that appear to play a key role in cancer and might be targets for future cancer drugs.

3 Dec 2013

Drugs News and Research

Rensselaer professors team up to develop innovative biomanufacturing technology

Scientists receive $12.5M NIH grant to continue research on targeted therapies for melanoma

Gladstone scientist devise new molecular sensor that can detect MS at earliest stages

LabCorp's HCV GenoSure NS3/4 test now available for Q80K polymorphism screening

Researchers find way to replace Paneth cells with two small molecules that maintain stem cells

Biotest, EpiVax partner to develop novel, non-immunogenic Factor VIII for hemophilia treatment

CUMC researchers make new breakthrough in regenerative medicine

EU pledges over $500 million to fight AIDS, TB and malaria

Microneedle technique may provide a painless way to deliver drugs, vaccines

Researchers offer promise of strategy for curing HIV infection

Scientists figure out how transporters work

New catalog brings interactions between pharmacological molecules and proteins

Research proves effectiveness of vaccine against leishmaniasis

New robot to guide surgery, needle insertion, catheters and stents

Scientists investigate factors that influence choice of abused drugs

Researchers use hyperthermia to treat patients with malignant glioma

IRCM researcher sheds light on inconsistencies between pharmacogenomic studies

New finding links obesity and high-fat, high-sugar diets with changes in inflammatory status

Oxygen levels play critical role in determining effectiveness of anti-inflammatory drugs

Scientists explain new family of proteins that appear to play key role in cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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