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Study demonstrates intrahost MPXV variation within a single lesion

Researchers reported on the clinical and molecular characteristics of MPXV infections in Finland.

31 Jan 2023

Impaired glucose tolerance and cardiovascular risk factors associated with fertility problems

The present study provided strong evidence that supported the hypothesis that hyperinsulinemia and glucose intolerance cause infertility in women.

31 Jan 2023

Study finds link between tumor microbiome and immune system in sarcoma patients

In a significant new study, UC Davis Comprehensive Cancer Center researchers have uncovered a link between a patient's microbiome and their immune system that can potentially be used to improve the treatment of soft tissue sarcoma.

30 Jan 2023

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Researchers identified serological Hepatitis C virus (HCV) signatures and human immunodeficiency virus (HIV) signatures through the secondary utilization of ribonucleic acid sequencing (RNA-seq) analysis data among previous and existing smokers with or without COPD (chronic obstructive pulmonary disease).

30 Jan 2023

Using systems biology research to alter the properties of carcinogenic cells in the lungs

KAIST (President Kwang Hyung Lee) announced on January 30th that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering succeeded in using systems biology research to change the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.

29 Jan 2023

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

A recent study evaluates the presence of SARS-CoV-2 in children’s tonsils during the COVID-19 pandemic.

29 Jan 2023

Researchers discover how measles virus can cause a rare but fatal neurological disorder

Researchers in Japan have uncovered the mechanism for how the measles virus can cause subacute sclerosing panencephalitis, or SSPE, a rare but fatal neurological disorder that can occur several years after a measles infection.

27 Jan 2023

DePaul and Rosalind Franklin fund research projects that bring together AI, biomedical discovery and health care

DePaul University and Rosalind Franklin University of Science and Medicine are funding three faculty research projects that bring together artificial intelligence, biomedical discovery and health care.

27 Jan 2023

Researchers identify an unexpected driver of cancer immunotherapy resistance

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signaling on tumor-killing CD8+ T cells.

27 Jan 2023

Research offers hope for patients affected by rare, hereditary metabolic disease

Methylmalonic aciduria (MMA) is a metabolic disorder that affects approximately one in 90,000 newborns; both parents must carry a genetic predisposition to the disease.

26 Jan 2023

Novel papillomaviruses identified in Malayan and Chinese pangolins

Researchers identify two novel lineages of papillomaviruses by mining the genome data of Chinese and Malayan pangolins.

26 Jan 2023

Scientists receive $2.9 million NIH grant to better understand the genetics of IBD in Hispanics

After studying the genetic sequences of more than 100,000 people, researchers around the country have started to uncover the root causes of inflammatory bowel disease (IBD), Crohn's disease, and ulcerative colitis.

26 Jan 2023

Study identifies the DNA roots of resistance to targeted cancer therapy

A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics.

26 Jan 2023

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

Study reveals the inevitability of Zika virus dumbbell-1 structure for viral pathogenesis

In a recent study posted to the bioRxiv* preprint server, researchers designed two dumbbell-1 (DB-1) mutant Zika virus (ZIKV) infectious clones termed ZIKV-TL.PK and ZIKV-p.2.5’.

26 Jan 2023

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Researchers performed a prospective case-control study on pregnant women with confirmed coronavirus disease 2019 (COVID-19).

26 Jan 2023

Researchers report on a genome-wide reconstruction of human microbes to develop personalized therapies

Researchers reported on AGORA2, an expansion of their previously published resource, AGORA, of genomewide metabolic reconstructions of human intestinal microbes.

26 Jan 2023

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital used a next-generation protein degradation technology to study CTCF.

26 Jan 2023

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

25 Jan 2023

New method analyzes long-range interactions in the interactome

Researchers at the Josep Carreras Leukaemia Research Institute have developed a method to analyze long-range interactions in the DNA -the interactome- from a very low amount of starting material.

25 Jan 2023

Genome News and Research

Study demonstrates intrahost MPXV variation within a single lesion

Impaired glucose tolerance and cardiovascular risk factors associated with fertility problems

Study finds link between tumor microbiome and immune system in sarcoma patients

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Using systems biology research to alter the properties of carcinogenic cells in the lungs

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

Researchers discover how measles virus can cause a rare but fatal neurological disorder

DePaul and Rosalind Franklin fund research projects that bring together AI, biomedical discovery and health care

Researchers identify an unexpected driver of cancer immunotherapy resistance

Research offers hope for patients affected by rare, hereditary metabolic disease

Novel papillomaviruses identified in Malayan and Chinese pangolins

Scientists receive $2.9 million NIH grant to better understand the genetics of IBD in Hispanics

Study identifies the DNA roots of resistance to targeted cancer therapy

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Study reveals the inevitability of Zika virus dumbbell-1 structure for viral pathogenesis

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Researchers report on a genome-wide reconstruction of human microbes to develop personalized therapies

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

New method analyzes long-range interactions in the interactome

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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