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New gene therapy for Pompe disease may replace currently available treatments

After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients.

27 Jan 2017

NIH scientists improve understanding of antibody-based protection against klebsiella bacteria

Klebsiella bacteria cause about 10 percent of all hospital-acquired infections in the United States. K. pneumoniae sequence type 258 (ST258) is one of the Carbapenem-Resistant Enterobacteriaceae organisms labeled an urgent threat by the Centers for Disease Control and Prevention.

27 Jan 2017

Body cooling not more effective than therapeutic normothermia for treating in-hospital cardiac arrests in children

In a multicenter, international study of infants and children who suffered cardiac arrest while in the hospital, NIH-funded researchers have found that body cooling, or therapeutic hypothermia, is no more effective than actively keeping the body at a normal temperature, or therapeutic normothermia.

25 Jan 2017

South African study shows that person-to person transmission drives drug-resistant TB epidemics

A study published today in The New England Journal of Medicine provides compelling evidence that extensively drug-resistant tuberculosis (XDR TB) is spread from person-to-person in the KwaZulu-Natal province, South Africa from 2011-2014.

20 Jan 2017

FDA approves new oral medication for treating chronic idiopathic constipation in adult patients

The U.S. Food and Drug Administration today approved Trulance (plecanatide) for the treatment of Chronic Idiopathic Constipation (CIC) in adult patients.

19 Jan 2017

Study shows evidence that person-to-person transmission drives spread of drug-resistant TB

19 Jan 2017

Influenza experts examine evolution of avian disease

Few influenza viruses are as widespread and adaptable as avian influenza viruses, and scientists are not entirely sure why.

19 Jan 2017

High-donor-volume hospitals more likely to have improved OTPD rate than low-volume medical centers

Hospitals that manage the highest volume of deceased organ donors are 52 percent more likely to recover an above-average number of transplantable organs per donor compared with low-volume hospitals, according to results from a new study conducted across three U.S. donation regions.

19 Jan 2017

More people with mental illness, substance use disorders have insurance coverage, research suggests

Significantly more people with mental illness and substance use disorders had insurance coverage in 2014 due to the expansion of health insurance under the Affordable Care Act, but many barriers to treatment remain, new Johns Hopkins Bloomberg School of Public Health research suggests.

18 Jan 2017

Scientists identify how early responses of immune system can affect development of EBOV disease

A new mouse model of early Ebola virus infection has shown National Institutes of Health (NIH) scientists and colleagues how early responses of the immune system can affect development of EBOV disease.

18 Jan 2017

Drug-resistant deadly bacteria more widespread than previously thought, study finds

A family of highly drug-resistant and potentially deadly bacteria may be spreading more widely--and more stealthily -- than previously thought, according to a new study from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.

17 Jan 2017

NCI launches new drug formulary to help expedite use of agents in clinical studies

The National Cancer Institute today launched a new drug formulary (the "NCI Formulary") that will enable investigators at NCI-designated Cancer Centers to have quicker access to approved and investigational agents for use in preclinical studies and cancer clinical trials.

11 Jan 2017

NIH highlights key tips and facts about glaucoma

January is Glaucoma Awareness Month. The National Eye Institute, part of NIH, is highlighting key facts about this blinding disease, important tips for prevention and treatment, and research updates you may not know about.

10 Jan 2017

New study explores impact of Affordable Care Act on socioeconomic disparities in cancer screening

Out-of-pocket expenditures are thought to be a significant barrier to receiving cancer preventive services, especially for individuals of lower socioeconomic status. A new study looks at how the Affordable Care Act (ACA), which eliminated such out-of-pocket expenditures, has affected the use of mammography and colonoscopy.

9 Jan 2017

Experts issue clinical guidelines to help early introduction of peanut-containing foods to infants

An expert panel sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, issued clinical guidelines today to aid health care providers in early introduction of peanut-containing foods to infants to prevent the development of peanut allergy.

5 Jan 2017

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

National Institutes of Health researchers have discovered molecular mechanisms that may underlie a woman's susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

3 Jan 2017

Parental obesity may increase children's risk for developmental delays, NIH study suggests

Children of obese parents may be at risk for developmental delays, according to a study by researchers at the National Institutes of Health.

2 Jan 2017

Fenofibrate drug may reduce risk of cardiovascular events in patients with type 2 diabetes

A new study shows that the drug fenofibrate might reduce the risk of cardiovascular events in patients with type 2 diabetes who have high levels of triglycerides and low levels of "good" cholesterol, despite being treated with statins.

29 Dec 2016

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

Four-year Johns Hopkins program provides efficient, less expensive care for patients in East Baltimore

When people with chronic health problems couldn't get around town to their doctors' appointments, a four-year Johns Hopkins program brought the appointments to them.

25 Dec 2016

Health and Human Services News and Research

New gene therapy for Pompe disease may replace currently available treatments

NIH scientists improve understanding of antibody-based protection against klebsiella bacteria

Body cooling not more effective than therapeutic normothermia for treating in-hospital cardiac arrests in children

South African study shows that person-to person transmission drives drug-resistant TB epidemics

FDA approves new oral medication for treating chronic idiopathic constipation in adult patients

Study shows evidence that person-to-person transmission drives spread of drug-resistant TB

Influenza experts examine evolution of avian disease

High-donor-volume hospitals more likely to have improved OTPD rate than low-volume medical centers

More people with mental illness, substance use disorders have insurance coverage, research suggests

Scientists identify how early responses of immune system can affect development of EBOV disease

Drug-resistant deadly bacteria more widespread than previously thought, study finds

NCI launches new drug formulary to help expedite use of agents in clinical studies

NIH highlights key tips and facts about glaucoma

New study explores impact of Affordable Care Act on socioeconomic disparities in cancer screening

Experts issue clinical guidelines to help early introduction of peanut-containing foods to infants

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

Parental obesity may increase children's risk for developmental delays, NIH study suggests

Fenofibrate drug may reduce risk of cardiovascular events in patients with type 2 diabetes

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

Four-year Johns Hopkins program provides efficient, less expensive care for patients in East Baltimore

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