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Ipsen's elafibranor recommended for use in patients with rare liver disease

Ipsen announced today that the National Institute for Health and Care Excellence (NICE) has recommended elafibranor 80mg tablets for the treatment of PBC in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy in adults unable to tolerate UDCA. This makes elafibranor the first medicine for PBC approved for use on the NHS in nearly a decade.

26 Oct 2024

New insights into rejection entities in kidney transplantation

Investigators recently uncovered key insights into newly defined rejection entities in kidney transplantation that may offer improved patient risk categorization post-transplant. The research will be presented at ASN Kidney Week 2024 October 23– 27.

25 Oct 2024

Are back problems influenced by your gut?

Findings suggest gut microbiome dysbiosis may influence lumbar degenerative spondylolisthesis, impacting inflammation and pain management strategies.

25 Oct 2024

Daily pistachio consumption linked to improved eye health

A new study from researchers at the Friedman School of Nutrition Science and Policy at Tufts University has found that consuming pistachios daily may significantly improve eye health by increasing macular pigment optical density (MPOD), due to the plant pigment lutein, a key factor in protecting the eyes from blue (visible) light and age-related damage.

24 Oct 2024

At-home phototherapy proves effective for psoriasis treatment

For decades, people with psoriasis have been treated in clinics with narrowband ultraviolet B phototherapy, or light therapy, to reduce sores, scales, and inflammation.

24 Oct 2024

Study links gut bacteria infection to Alzheimer's disease progression

A groundbreaking study by researchers at Florida State University's Gut Biome Lab has revealed a potential link between an infection caused by gut bacteria and the progression of Alzheimer's disease.

24 Oct 2024

Researchers develop first-of-its-kind therapy to enhance heart repair after a heart attack

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind experimental therapy that has the potential to enhance heart repair following a heart attack, preventing the onset of heart failure.

24 Oct 2024

Gut health and diet: Keys to treating acne, alopecia, and dermatitis

Consuming diets rich in fiber, antioxidants, and phytonutrients, combined with the use of probiotics, synbiotics, and postbiotics, improves overall skin health.

24 Oct 2024

Long-term air pollution exposure linked to increased risk of acute kidney injury and mortality

Prolonged exposure to air pollutants like PM2.5 and nitrogen oxides significantly raises acute kidney injury risk and related mortality, urging policy action.

24 Oct 2024

Arthritis-style immunotherapy shows promise for heart failure

A study uncovers IL-1β signaling in cardiac fibrosis, highlighting distinct fibroblast populations and promising immunotherapy strategies for heart failure.

24 Oct 2024

Repeated mRNA vaccinations enhance mucosal antibody production

During the COVID pandemic, many of us have received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.

23 Oct 2024

Multiple courses of penicillin antibiotics linked to lower risk of Parkinson's disease

A Rutgers Health study has found that people who took multiple courses of penicillin antibiotics had a modestly lower risk of developing Parkinson's disease, a surprising finding that researchers say highlights the complex relationship between bacteria in the digestive tract and brain health.

23 Oct 2024

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy - similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis - also may be an effective treatment strategy for heart failure.

23 Oct 2024

The importance of women's oral health in overall wellbeing

Women's oral health is about more than just a beautiful smile—it's a critical aspect of overall wellbeing that is often overlooked.

23 Oct 2024

Physical tests offer prognostic insights for lung cancer patients

A study of patients with metastatic lung cancer by researchers based in Brazil and the United States has found that their performance in simple physical tests such as sitting down, standing and walking can help physicians arrive at a prognosis and approach to treatment.

22 Oct 2024

Structural biology reveals secrets of DEV phage infection

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

22 Oct 2024

AI models match ophthalmologists in diagnosing infectious keratitis

Eye care specialists could see artificial intelligence help in diagnosing infectious keratitis (IK), a leading cause of corneal blindness worldwide, as a new study finds that deep learning models showed similar levels of accuracy in identifying infection.

22 Oct 2024

Ultra-processed foods linked to liver disease and insulin resistance in obese children

Ultra-processed food consumption in obese adolescents is linked to insulin resistance and liver disease, stressing the need for improved dietary interventions.

22 Oct 2024

Telemedicine and low-carb diet slashes diabetes meds and drives lasting remission

A five-year study on a low-carbohydrate, remote care intervention for type 2 diabetes shows significant improvements in diabetes remission, weight loss, and cardiometabolic health, reducing the need for medications.

22 Oct 2024

Long-term antiviral treatment may protect vision from shingles

Taking an antiviral medication for a year may prevent vision damage associated with shingles that affects the eye, according to new research led by faculty from the Perelman School of Medicine at the University of Pennsylvania and the NYU Grossman School of Medicine.

21 Oct 2024