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Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Committee for Medicinal Products for Human Use has adopted a Positive Opinion recommending marketing authorization of patisiran for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

27 Jul 2018

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

UCSF Benioff Children's Hospital Oakland clinical researchers, in conjunction with other sickle cell centers and scientists at Emmaus Life Sciences, Inc., have demonstrated that therapy with L-Glutamine reduced the frequency of pain episodes in both pediatric and adult patients with sickle cell disease.

27 Jul 2018

New drug discovery system allows scientists to target ‘undruggable’ enzymes

A new drug discovery system allows scientists to specifically target members of an important family of enzymes, called phosphatases, which were previously considered mostly "undruggable".

27 Jul 2018

New drug offers hope to prevent attacks of hereditary angioedema

Hereditary angioedema is a chronic disorder that can sometimes be life-threatening. Now, a new drug therapy has been successfully tested in an international study headed by the University Hospital Frankfurt.

26 Jul 2018

Ciprofloxacin may disrupt normal functions of connective tissue

The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment

26 Jul 2018

Pivotal study of dasotraline in adults with binge eating disorder meets primary endpoint

Sunovion Pharmaceuticals Inc. today announced that a study evaluating the efficacy and safety of dasotraline in adults with moderate to severe binge eating disorder met its primary endpoint, demonstrating a statistically significant decrease in number of binge days per week from baseline to Week 12 in the group treated with dasotraline 6 mg/day versus the placebo-treated group.

25 Jul 2018

Viagra in pregnancy trial stopped after 11 newborn babies died

A Dutch clinical trial was looking at the potential of Sildenafil or impotence drug Viagra to improve the growth in unborn babies of pregnant women. The study had to be stopped prematurely after the death of eleven babies.

25 Jul 2018

Common opioid-based painkillers increase harmful side effects in people with dementia

Commonly-prescribed opioid-based painkillers led to harmful side effects tripling in people with dementia.

24 Jul 2018

New study finds brain mechanisms underlying food cravings

A newly published study from the University of Waterloo shows that when activity in a specific part of the brain is suppressed, our desire for high-calorie foods increases.

23 Jul 2018

Researchers study efficacy and safety of new treatment for OUD

Better delivery of medications to treat opioid use disorder is key to addressing the opioid crisis and helping the 2.6 million Americans affected by the disease.

20 Jul 2018

ADHD medications may fail to improve cognition in healthy college students, study shows

Contrary to popular belief across college campuses, attention deficit hyperactivity disorder medications may fail to improve cognition in healthy students and actually can impair functioning, according to a study by researchers at the University of Rhode Island and Brown University.

20 Jul 2018

New Finnish study compares surgical treatment of shoulder impingement syndrome to placebo surgery

In a landmark study published this week in the BMJ, Finnish researchers show that one of the most common surgical procedures in the Western world is probably unnecessary.

19 Jul 2018

New clinical trial examines use of adrenaline to treat cardiac arrests

A clinical trial of the use of adrenaline in cardiac arrests has found that its use results in less than 1% more people leaving hospital alive - but almost doubles the risk of severe brain damage for survivors of cardiac arrest.

19 Jul 2018

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

Pfizer Inc. and Eli Lilly and Company today announced that a 16-week Phase 3 study in patients with osteoarthritis pain evaluating subcutaneous administration of tanezumab, an investigational humanized monoclonal antibody, met all three co-primary endpoints.

19 Jul 2018

New findings do no support caffeine as effective appetite suppressant or weight-loss aid

A new study featured in the Journal of the Academy of Nutrition and Dietetics found that after drinking a small amount of caffeine, participants consumed 10 percent less at a breakfast buffet provided by researchers, but this effect did not persist throughout the day and had no impact on participants' perceptions of their appetites.

19 Jul 2018

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

The U.S. Food and Drug Administration today approved Kisqali (ribociclib) in combination with an aromatase inhibitor for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy.

19 Jul 2018

Increasing blood sugar levels improves memory and performance in older adults

Sugar improves memory in older adults - and makes them more motivated to perform difficult tasks at full capacity - according to new research by the University of Warwick.

18 Jul 2018

New study demonstrates little effect of hormone therapy on artery thickness

Heart disease is still the number one killer of US women, and hormone therapy remains a top treatment for menopause symptoms.

18 Jul 2018

Testosterone effective at fighting cachexia in cancer patients, research shows

Many cancer patients suffer from a loss of body mass known as cachexia. Approximately 20 percent of cancer-related deaths are attributed to the syndrome of cachexia, which in cancer patients is often characterized by a rapid and/or severe loss of fat and skeletal muscle.

13 Jul 2018

Captozyme begins cross-over study of Nephure oxalate reducing enzyme

Captozyme, Inc. announced today that it is initiating a prospective double-blind, randomized, placebo controlled, cross-over study, with Nephure, an oxalate reducing enzyme, to determine the extent to which Nephure vs. placebo reduces urinary oxalate excretion (mg/24 hour) in healthy subjects who are provided a controlled diet.

12 Jul 2018

Placebo News and Research

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

New drug discovery system allows scientists to target ‘undruggable’ enzymes

New drug offers hope to prevent attacks of hereditary angioedema

Ciprofloxacin may disrupt normal functions of connective tissue

Pivotal study of dasotraline in adults with binge eating disorder meets primary endpoint

Viagra in pregnancy trial stopped after 11 newborn babies died

Common opioid-based painkillers increase harmful side effects in people with dementia

New study finds brain mechanisms underlying food cravings

Researchers study efficacy and safety of new treatment for OUD

ADHD medications may fail to improve cognition in healthy college students, study shows

New Finnish study compares surgical treatment of shoulder impingement syndrome to placebo surgery

New clinical trial examines use of adrenaline to treat cardiac arrests

Phase 3 study of tanezumab in patients with osteoarthritis pain meets all three co-primary endpoints

New findings do no support caffeine as effective appetite suppressant or weight-loss aid

FDA grants approval for first breast cancer drug through 'Real-Time Oncology Review'

Increasing blood sugar levels improves memory and performance in older adults

New study demonstrates little effect of hormone therapy on artery thickness

Testosterone effective at fighting cachexia in cancer patients, research shows

Captozyme begins cross-over study of Nephure oxalate reducing enzyme

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