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New database helps identify therapeutic targets to fight infectious diseases

Infectious diseases are caused by pathogenic microorganisms capable of entering, colonizing and growing within a host organism, thus producing an infection. Bacterial infections have been on the rise worldwide in recent years, but many mechanisms underlying bacterial pathogenesis are still poorly understood.

19 Nov 2019

New technology may offer alternative means of profiling tissues

Current cancer treatment courses often begin with tissue biopsies. Biopsies, however, which involve the physical resection of a small tissue sample, can lead to localized tissue injury, bleeding, inflammation, and stress, as well as increased risk of metastasis.

19 Nov 2019

TARA's organ-on-a-chip technology can directly measure in vivo cardiac performance, study shows

TARA Biosystems, Inc. today reported in vivo and in vitro functional data from a study of investigational candidate, MYK-491, showing that TARA's human iPSC-derived organ-on-a-chip technology can directly measure in vivo cardiac performance.

18 Nov 2019

Blocking a molecule could delay the progression of multiple sclerosis

Over 77,000 Canadians are living with multiple sclerosis, a disease whose causes still remain unknown. Presently, they have no hope for a cure.

14 Nov 2019

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

13 Nov 2019

Deep neural network could improve cancer care

Improving the detection, diagnosis, and treatment of diseases like cancer will require more detailed, rapid, and agile imaging technology that can show doctors not just what a specific organ looks like, but also what's happening within the cells that make up those tissues.

13 Nov 2019

Virginia Tech professor wins $1.85 million NIH grant for sepsis research

One drop of blood contains 5,000 neutrophils, the most abundant type of white blood cell that is deployed by the human immune system. Throughout the entire body, a human has 25 billion of these foot soldiers that are relentlessly patrolling to fight invading pathogens.

12 Nov 2019

Researchers reveal non-image light sensing mechanism of circadian neurons using fruit flies

University of California, Irvine researchers reveal how an ancient flavoprotein response to ultra violet (UV), blue and red light informs internal circadian processes about the time of day.

7 Nov 2019

CRISPR-Cas9 protein can help increase targeting accuracy in genome editing process

A team of researchers from City University of Hong Kong and Karolinska Institutet has recently developed a new protein that can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for future gene therapies in human, which require high precision.

6 Nov 2019

Gene-editing technique CRISPR trialed for first time as cancer treatment

The go-ahead has been given for the first trials using CRISPR as an alternative therapy for treating cancer.

6 Nov 2019

Study: Spherical exosomes could help in treating acute kidney injury

Like a swarm of construction workers in the aftermath of a destructive storm, cargo-filled, nanometer-sized spheres arrive on the scene following an acute kidney injury.

5 Nov 2019

New innovations in technology aim to improve treatment of PTSD among veterans

New technology aims to improve the treatment of post-traumatic stress disorder by allowing veterans to virtually take their doctor with them during prolonged exposure therapy. The system gives the doctor physical and psychological information about the veterans in real time.

2 Nov 2019

New study may help better understand mechanisms that control blood pressure

Many questions remain about the mechanisms that control blood pressure, particularly in relation to hypertension.

1 Nov 2019

Scientists propose new material for regenerative medicine capable of controlling immune response

Scientists of Tomsk Polytechnic University jointly with the University of Montana proposed a new promising material for regenerative medicine for recovery of damaged tissues and blood vessels.

1 Nov 2019

Malaria parasite with Quinoline drug investigated in-vivo

Researchers from Israel, in collaboration with others looked at the effects of the malaria plasmodium on red blood cells in vivo in presence of a drug, to understand the workings of the pathogen in its disease causing ability and also lay foundation for development of effective treatment for the deadly disease.

31 Oct 2019

MGH researchers create highest resolution MRI scan of the human brain

A new paper describes a breakthrough 100 micron resolution scan of the human brain that was created by a multidisciplinary team of Massachusetts General Hospital researchers.

30 Oct 2019

Syringe-injectable, self-expandable and ultraconformable magnetic nanosheets developed

Syringe-injectable biomaterials, medical devices and engineered tissues have attracted great attention as minimally-invasive implants for diagnosis, therapy and regenerative medicine.

30 Oct 2019

Humanized skin model answers questions about transient carriers of MRSA

Using a humanized model, researchers have discovered why some people are only transient carriers of the superbug, MRSA.

30 Oct 2019

TDP-43 study could speed up the diagnosis and treatment of ALS

A new study suggests that TDP-43 may be used as a biomarker in the diagnosis and treatment of amyotrophic lateral sclerosis (ALS).

30 Oct 2019

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

in vivo News and Research

New database helps identify therapeutic targets to fight infectious diseases

New technology may offer alternative means of profiling tissues

TARA's organ-on-a-chip technology can directly measure in vivo cardiac performance, study shows

Blocking a molecule could delay the progression of multiple sclerosis

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

Deep neural network could improve cancer care

Virginia Tech professor wins $1.85 million NIH grant for sepsis research

Researchers reveal non-image light sensing mechanism of circadian neurons using fruit flies

CRISPR-Cas9 protein can help increase targeting accuracy in genome editing process

Gene-editing technique CRISPR trialed for first time as cancer treatment

Study: Spherical exosomes could help in treating acute kidney injury

New innovations in technology aim to improve treatment of PTSD among veterans

New study may help better understand mechanisms that control blood pressure

Scientists propose new material for regenerative medicine capable of controlling immune response

Malaria parasite with Quinoline drug investigated in-vivo

MGH researchers create highest resolution MRI scan of the human brain

Syringe-injectable, self-expandable and ultraconformable magnetic nanosheets developed

Humanized skin model answers questions about transient carriers of MRSA

TDP-43 study could speed up the diagnosis and treatment of ALS

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

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