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Updated EULAR recommendations for management of rheumatoid arthritis

The European League Against Rheumatism has released updated recommendations for the management of RA. According to this latest guidance, treatment with disease-modifying anti-rheumatic drugs should be initiated as soon as a diagnosis of RA is made, with the aim of reaching a target of remission or low disease activity in every patient.

4 Jul 2013

MGN1703 drug provides a new treatment approach to colorectal cancer

New data on an emerging treatment that aims to fight colorectal cancer by stimulating the immune system have been presented at the ESMO 15th World Congress on Gastrointestinal Cancer.

4 Jul 2013

GAPVAC aims to develop personalized therapeutic vaccines for cancer

A highly innovative project supported by a €6 million European Union Framework 7 (EU FP7) program grant to develop a novel class of therapeutic cancer vaccines is now under way.

4 Jul 2013

Professor receives grant to explore therapeutic agent, treatment method for brain cancer

The problem with cancer treatments designed to kill a tumor is that they can kill the patient's quality of life as well. Now a Florida State University College of Medicine researcher is shifting the focus from eradicating brain tumors to managing them.

4 Jul 2013

FDA approves Orexo's Zubsolv for people suffering from opioid dependence

Orexo today announced that it has received approval from the U.S. Food and Drug Administration for Zubsolv (buprenorphine/naloxone) sublingual tablet CIII.

4 Jul 2013

Adding chemotherapy after surgery for patients with advanced gastric cancer can reduce mortality risk

For patients with advanced gastric cancer, treatment with chemotherapy after surgery can reduce the risk of cancer related death by 34% over five years compared to surgery alone, researchers said at the 15th ESMO World Congress in Gastrointestinal Cancer.

4 Jul 2013

Assay identifies T cells as most capable of fighting infections and cancers

The idea of fighting infections and even cancers by inducing protective immune responses may now be a step closer to clinical practice. Researchers have removed a major obstacle to widespread use of so-called adoptive transfer therapy, in which a patient receives "killer" immune cells targeting a disease agent. Existing technologies can easily provide T cells that will recognize a specific antigen, but it has been challenging to identify individual cells most likely to succeed in fighting the disease - until now.

4 Jul 2013

3-gene signature test will improve care of kidney transplant patients

A breakthrough non-invasive test can detect whether transplanted kidneys are in the process of being rejected, as well as identify patients at risk for rejection weeks to months before they show symptoms, according to a study published in The New England Journal of Medicine (NEJM).

4 Jul 2013

Research shows lower daily dose of HIV drug therapy suppresses virus

Millions more people could get access to life-saving HIV drug therapy, following a landmark study led by Australian researchers based at the Kirby Institute at the University of New South Wales (UNSW).

4 Jul 2013

First Edition: July 3, 2013

Today's headlines detail the Obama administration announcement that it would delay the health law rule requiring businesses provide insurance to workers.

3 Jul 2013

Genentech's obinutuzumab gets FDA Priority Review for chronic lymphocytic leukemia

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has accepted the company's Biologics License Application for obinutuzumab (GA101) and granted Priority Review for GA101 in the treatment of chronic lymphocytic leukemia, one of the most common forms of blood cancer, based on final Stage 1 data from the pivotal CLL11 trial.

3 Jul 2013

Telemonitoring with pharmacist management improves and maintains BP control

An intervention that consisted of home blood pressure (BP) telemonitoring with pharmacist management resulted in improvements in BP control and decreases in BP during 12 months, compared with usual care, and improvement in BP that was maintained for 6 months following the intervention, according to a study in the July 3 issue of JAMA.

3 Jul 2013

Data on side effects of fidaxomicin not analysed appropriately

The antibiotic fidaxomicin (trade name: Dificlir) has been approved in Germany since December 2011 for the treatment of adults who have diarrhoea caused by Clostridium difficile.

3 Jul 2013

Home-based exercise intervention improves walking performance, physical activity in PAD patients

In a trial that included nearly 200 participants with peripheral artery disease, a home-based exercise intervention with a group-mediated cognitive behavioral intervention component improved walking performance and physical activity in patients with PAD, according to a study in the July 3 issue of JAMA.

3 Jul 2013

LARIAT procedure prevents stroke in patients who are unable to tolerate blood thinners

Jersey Shore University Medical Center is one of only a handful of hospitals in the country offering the recent FDA-approved LARIAT Suture Delivery Device procedure. Electrophysiologists and interventional cardiologists perform this innovative procedure to help prevent stroke in patients who suffer from atrial fibrillation and are unable to take blood thinners.

3 Jul 2013

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

Yale Cancer Center scientists, together with colleagues at the Denver Police Crime Lab and the University of Colorado, have found evidence that a human metastatic tumor can arise when a leukocyte (white blood cell) and a cancer cell fuse to form a genetic hybrid.

3 Jul 2013

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Scientists found genetic variations that could be used to identify women who are most likely to benefit from a certain type of breast cancer prevention drug—and who should avoid it.

3 Jul 2013

Biogen, Sobi present new findings from Phase 3 trial of ALPROLIX at XXIV ISTH Congress

Biogen Idec and Swedish Orphan Biovitrum AB (publ) today presented new findings for their long-lasting recombinant factor IX candidate ALPROLIX for hemophilia B at the XXIV International Society on Thrombosis and Haemostasis Congress in Amsterdam, The Netherlands.

3 Jul 2013

Pitt researchers propose mathematical model that examines multiple walking patterns in older adults

Older adults diagnosed with brain disorders such as Parkinson's disease often feel a loss of independence because of their lack of mobility and difficulty walking.

3 Jul 2013

Abiraterone can prolong overall survival and delay severe pain in prostate cancer patients

Abiraterone acetate (abiraterone for short, trade name: Zytiga) has been approved in Germany since December 2012 for men with metastatic prostate cancer that is not responsive to hormone blockade, who only have mild symptoms or so far none at all, and in whom chemotherapy is not yet indicated.

3 Jul 2013

Therapy News and Research

Updated EULAR recommendations for management of rheumatoid arthritis

MGN1703 drug provides a new treatment approach to colorectal cancer

GAPVAC aims to develop personalized therapeutic vaccines for cancer

Professor receives grant to explore therapeutic agent, treatment method for brain cancer

FDA approves Orexo's Zubsolv for people suffering from opioid dependence

Adding chemotherapy after surgery for patients with advanced gastric cancer can reduce mortality risk

Assay identifies T cells as most capable of fighting infections and cancers

3-gene signature test will improve care of kidney transplant patients

Research shows lower daily dose of HIV drug therapy suppresses virus

First Edition: July 3, 2013

Genentech's obinutuzumab gets FDA Priority Review for chronic lymphocytic leukemia

Telemonitoring with pharmacist management improves and maintains BP control

Data on side effects of fidaxomicin not analysed appropriately

Home-based exercise intervention improves walking performance, physical activity in PAD patients

LARIAT procedure prevents stroke in patients who are unable to tolerate blood thinners

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Biogen, Sobi present new findings from Phase 3 trial of ALPROLIX at XXIV ISTH Congress

Pitt researchers propose mathematical model that examines multiple walking patterns in older adults

Abiraterone can prolong overall survival and delay severe pain in prostate cancer patients

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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