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Biologists reveal how bacterial cells thrive in oxygen-poor environments

Columbia University biologists have revealed a mechanism by which bacterial cells in crowded, oxygen-deprived environments access oxygen for energy production, ensuring survival of the cell. The finding could explain how some bacteria, such as Pseudomonas aeruginosa (P. aeruginosa), are able to thrive in oxygen-poor environments like biofilms and resist antibiotics.

21 Nov 2017

Drug could be repurposed to help end transplant rejection

A diabetes drug currently undergoing development could be repurposed to help end transplant rejection, without the side-effects of current immunosuppressive drugs, according to new research by Queen Mary University of London.

21 Nov 2017

UNC Lineberger professor receives The Leukemia & Lymphoma Society grant for immunotherapy research

UNC Lineberger Comprehensive Cancer Center researcher Barbara Savoldo, MD, PhD, was awarded a $600,000, three-year grant from The Leukemia & Lymphoma Society to support research into an immunotherapy treatment being developed with a "safety switch" to safeguard against potential side effects of the treatment.

21 Nov 2017

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

University of Colorado Boulder researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases by inhibiting a protein instrumental in prompting the body to start attacking its own tissue.

21 Nov 2017

Simple test could help predict best treatment for cystic fibrosis patients

Several cutting-edge treatments have become available in recent years to correct the debilitating chronic lung congestion associated with cystic fibrosis. While the new drugs are life-changing for some patients, they do not work for everyone.

21 Nov 2017

Unusual snapping turtle study enhances understanding of congenital lung abnormality

A study of an unusual snapping turtle with one lung found shared characteristics with humans born with one lung who survive beyond infancy. Digital 3D anatomical models created by Emma Schachner, PhD, Assistant Professor of Cell Biology & Anatomy at LSU Health New Orleans School of Medicine, made the detailed research possible.

21 Nov 2017

Scientists develop novel technology that uses CRISPR to map genetic mutations

A team of scientists led by Virginia Commonwealth University physicist Jason Reed, Ph.D., have developed new nanomapping technology that could transform the way disease-causing genetic mutations are diagnosed and discovered.

21 Nov 2017

Researchers identify previously unknown breast cell types

A joint effort by breast cancer researchers and bioinformaticians has provided new insights into the molecular changes that drive breast development.

21 Nov 2017

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts.

21 Nov 2017

Anti-diabetic drug can enhance repair of UV-induced DNA damage in cells of ‘Moon children’

The destructive force of UV radiation on DNA molecules is only fully visible, when repair mechanisms fail: patients with the rare genetic disease Xeroderma pigmentosum - also known as 'Moon children' - develop inflammations upon exposure to only small amounts of sunlight, rough-surfaced growths and eventually skin cancer occurs often in early age.

21 Nov 2017

New mechanism in cancer cells to disarm attacking immune cells, study reveals

A new study, published in the Journal of Clinical Investigation, identified a substance Gdf-15, which is secreted by pancreatic cancer cells and shields cancerous cells from attack by immune cells known as macrophages.

21 Nov 2017

Study identifies substance released by pancreatic cancer cells to disarm attacking macrophages

A new study by researchers at The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute identifies a substance released by pancreatic cancer cells that protect them from attack by immune cells called macrophages.

21 Nov 2017

Maintaining adequate vitamin D may help prevent onset of inflammatory diseases

Maintaining sufficient vitamin D levels may help to prevent the onset of inflammatory diseases like rheumatoid arthritis, research led by the University of Birmingham has discovered.

21 Nov 2017

Research paves way for development of vaccines against mycoplasma bacteria

Mycoplasma bacteria are one of the most common causes of bacterial pneumonia in children. It is still unclear how the disease develops.

21 Nov 2017

Probing living cells with AFM

An interview with Prof. David Alsteens, Université Catholique de Louvain conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 21 Nov 2017

Scientists develop new method to study Creutzfeldt-Jakob disease in the lab

Scientists have developed a new system to study Creutzfeldt-Jakob disease in the laboratory, paving the way for research to find treatments for the fatal brain disorder.

20 Nov 2017

UVA scientists working to find end-around method to stop triple-negative breast cancer

So-called "triple-negative" breast cancer is a particularly aggressive and difficult-to-treat form. It accounts for only about 10 percent of breast cancer cases, but is responsible for about 25 percent of breast cancer fatalities.

20 Nov 2017

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

D. Brent Polk, MD, AGAF, an investigator at Children's Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

20 Nov 2017

New technique may reveal clues about role of centromeres in Down syndrome, other birth defects

Some scientists call it the "final frontier" of our DNA -- even though it lies at the center of every X-shaped chromosome in nearly every one of our cells.

20 Nov 2017

Gold nanoparticles could potentially help in more effective drug delivery

Gold nanoparticles could help make drugs act more quickly and effectively, according to new research conducted at Binghamton University, State University of New York.

20 Nov 2017

B Cell News and Research

Biologists reveal how bacterial cells thrive in oxygen-poor environments

Drug could be repurposed to help end transplant rejection

UNC Lineberger professor receives The Leukemia & Lymphoma Society grant for immunotherapy research

Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases

Simple test could help predict best treatment for cystic fibrosis patients

Unusual snapping turtle study enhances understanding of congenital lung abnormality

Scientists develop novel technology that uses CRISPR to map genetic mutations

Researchers identify previously unknown breast cell types

Liver disease in children with Alagille Syndrome caused by malformations of bile ducts

Anti-diabetic drug can enhance repair of UV-induced DNA damage in cells of ‘Moon children’

New mechanism in cancer cells to disarm attacking immune cells, study reveals

Study identifies substance released by pancreatic cancer cells to disarm attacking macrophages

Maintaining adequate vitamin D may help prevent onset of inflammatory diseases

Research paves way for development of vaccines against mycoplasma bacteria

Probing living cells with AFM

Scientists develop new method to study Creutzfeldt-Jakob disease in the lab

UVA scientists working to find end-around method to stop triple-negative breast cancer

Researcher awarded $1.5 million to study role of tumor necrosis factor in IBD

New technique may reveal clues about role of centromeres in Down syndrome, other birth defects

Gold nanoparticles could potentially help in more effective drug delivery

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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