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Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

A protein first shown to function in the liver plays a crucial role in pregnancy in mice and has a key role in the human menstrual cycle, according to researchers at the University of Montreal. Mice that were genetically engineered not to produce the liver receptor homolog-1 (Lrh-1) molecule were unable to create the uterine conditions necessary for establishing and sustaining pregnancy, resulting in the formation of defective placentas.

1 Jul 2013

Research: Systemic dose of dendritic cells prevent rejection in kidney transplantation

A single systemic dose of special immune cells prevented rejection for almost four months in a preclinical animal model of kidney transplantation, according to experts at the University of Pittsburgh School of Medicine.

1 Jul 2013

Biomarker indicates which women are at risk for breast cancer recurrence after tamoxifen

A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor (ER)-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment.

30 Jun 2013

RPCI scientists assess safety and efficacy of immunotherapy approach to treat advanced melanoma

A new clinical research study at Roswell Park Cancer Institute (RPCI) will assess the safety and efficacy of a novel immunotherapy approach to treating advanced melanoma. Developed at RPCI by Roswell Park researchers, the investigational vaccine shows promise for treating tumors in patients with stage III/stage IV melanoma, and perhaps as a future therapy for other solid-tumor cancers as well.

30 Jun 2013

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

A study carried out in India examining the safety and efficacy of self-donated (autologous), transplanted bone marrow stem cells in patients with type 2 diabetes (TD2M), has found that patients receiving the transplants, when compared to a control group of TD2M patients who did not receive transplantation, required less insulin post-transplantation.

30 Jun 2013

Test-based approach of WHO unsuitable for regions where lot of malaria occurs: Research

In view of the sharp rise in treatment costs of malaria, the World Health Organization says that there must be a hard diagnosis before the disease is treated.

29 Jun 2013

Mount Sinai becomes first NYC medical center to use new HeartMate II controller in heart failure patients

The Mount Sinai Medical Center is the first medical center in New York City to offer the newly FDA approved HeartMate II® Pocket Controller™ to help its advanced heart failure patients maintain more active lifestyles.

29 Jun 2013

Researchers complete 25-year follow-up study on infants with iron deficiency in Costa Rica

Iron deficiency is a worldwide problem, especially in developing countries and among infants and pregnant women. In infancy, iron deficiency is associated with poorer cognitive, motor, and social-emotional outcomes. In a new study scheduled for publication in The Journal of Pediatrics, researchers report on a 25-year follow-up of infants studied in Costa Rica for iron deficiency.

29 Jun 2013

Researchers investigate enteral nutrition, caloric requirements among critically ill children

For the first time, researchers investigated enteral nutrition and caloric requirements (CR) among critically ill children in a new report published in the Journal of the Academy of Nutrition and Dietetics. This study also showed the value of including registered dietitians in the medical team.

28 Jun 2013

'Sleep Mask' prototype: The world's first non-invasive treatment for sight loss

Rt Hon David Willetts MP has seen the 'Sleep Mask' prototype - the world's first non-invasive treatment for sight loss that will save the need for expensive hospital treatment - at Northumbria University's Northern Design Centre (NDC).

28 Jun 2013

Rural women with breast cancer less likely to receive radiation therapy after lumpectomy

Rural women with breast cancer are less likely than their urban counterparts to receive recommended radiation therapy after having a lumpectomy, a breast-sparing surgery that removes only tumors and surrounding tissue, a study by Mayo Clinic and others found.

28 Jun 2013

Computer simulation for predicting effectiveness of combination therapies for colon tumors

Scientist at Charité - Universitätsmedizin Berlin have used a computer simulation for predicting the effectiveness of various combination therapies for colon tumors. The study has been published in the current issue of the professional journal Molecular Systems Biology*.

28 Jun 2013

EMA's CHMP issues positive opinion for approval of Genzyme's LEMTRADA in Europe

Genzyme, a Sanofi company, announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has issued a positive opinion for approval of LEMTRADA (alemtuzumab) for the treatment of adult patients with relapsing remitting multiple sclerosis with active disease defined by clinical or imaging features.

28 Jun 2013

Janssen receives complete response letter from FDA for XARELTO sNDA

Janssen Research & Development, LLC today announced the U.S. Food and Drug Administration has issued a complete response letter for the supplemental New Drug Application for XARELTO (rivaroxaban) to reduce the risk of stent thrombosis in patients with acute coronary syndrome.

28 Jun 2013

Parkland Health Mart Pharmacy honored with McKesson's Pharmacy of the Year award

McKesson Corporation announced that its 2013 Pharmacy of the Year grand prize winner is Parkland Health Mart Pharmacy, located in Desloge, Missouri. Parkland Health Mart Pharmacy was honored in a special awards ceremony during the Opening General Session at the 2013 McKesson ideaShare conference.

28 Jun 2013

Hospira receives positive opinion from EMA's CHMP for EC approval of Inflectra

Hospira, the world's leading provider of injectable drugs and infusion technologies, today received a positive opinion from the European Medicines Agency Committee for Medicinal Products for Human Use, recommending the European Commission approval of Inflectra (infliximab) for rheumatoid arthritis, inflammatory bowel disease and plaque psoriasis.

28 Jun 2013

UH Eye Institute to use Argus II Retinal Prosthesis System to treat patients with RP

University Hospitals Eye Institute will be one of the first medical centers in the United States to offer the Argus II Retinal Prosthesis System.

28 Jun 2013

Study shows that individuals with SAD misreport sleep patterns due to depression

Lying awake in bed plagues everyone occasionally, but for those with seasonal affective disorder, sleeplessness is routine. University of Pittsburgh researchers report in the Journal of Affective Disorders that individuals with seasonal affective disorder -a winter depression that leads to loss of motivation and interest in daily activities-have misconceptions about their sleep habits similar to those of insomniacs.

28 Jun 2013

Ritalin helps improve brain function in cocaine addiction

A single dose of a commonly-prescribed attention deficit hyperactivity disorder drug helps improve brain function in cocaine addiction, according to an imaging study conducted by researchers from the Icahn School of Medicine at Mount Sinai.

28 Jun 2013

FDA approves Novartis' Exelon Patch for treatment of severe Alzheimer's disease

The US Food and Drug Administration has expanded the approved indication for Exelon Patch (rivastigmine transdermal system) to include the treatment of people with severe Alzheimer's disease with Exelon Patch 13.3mg/24h.

28 Jun 2013

Therapy News and Research

Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

Research: Systemic dose of dendritic cells prevent rejection in kidney transplantation

Biomarker indicates which women are at risk for breast cancer recurrence after tamoxifen

RPCI scientists assess safety and efficacy of immunotherapy approach to treat advanced melanoma

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

Test-based approach of WHO unsuitable for regions where lot of malaria occurs: Research

Mount Sinai becomes first NYC medical center to use new HeartMate II controller in heart failure patients

Researchers complete 25-year follow-up study on infants with iron deficiency in Costa Rica

Researchers investigate enteral nutrition, caloric requirements among critically ill children

'Sleep Mask' prototype: The world's first non-invasive treatment for sight loss

Rural women with breast cancer less likely to receive radiation therapy after lumpectomy

Computer simulation for predicting effectiveness of combination therapies for colon tumors

EMA's CHMP issues positive opinion for approval of Genzyme's LEMTRADA in Europe

Janssen receives complete response letter from FDA for XARELTO sNDA

Parkland Health Mart Pharmacy honored with McKesson's Pharmacy of the Year award

Hospira receives positive opinion from EMA's CHMP for EC approval of Inflectra

UH Eye Institute to use Argus II Retinal Prosthesis System to treat patients with RP

Study shows that individuals with SAD misreport sleep patterns due to depression

Ritalin helps improve brain function in cocaine addiction

FDA approves Novartis' Exelon Patch for treatment of severe Alzheimer's disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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