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FDA grants marketing approval for VALCHLOR gel for treatment of early stage CTCL

Ceptaris Therapeutics, Inc., a privately held, specialty pharmaceutical company, announced today that the U.S. Food and Drug Administration has granted marketing approval for the orphan drug VALCHLOR (mechlorethamine) gel for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma in patients who have received prior skin-directed therapy.

26 Aug 2013

Mayo Clinic opens its own stem cell laboratory in summer 2014

Mayo Clinic in Arizona, with one of the most active bone marrow transplant programs in United States, will open its own stem cell laboratory in summer 2014. The laboratory will be initially dedicated to storing and processing stem cells used for bone marrow transplants at Mayo Clinic Hospital and Phoenix Children's Hospital.

26 Aug 2013

Scientists discover mechanisms of GATA3 gene that govern blood stem cell self-renewal process

Stem cell scientists at the Princess Margaret Cancer Centre have discovered the gene GATA3 has a role in how blood stem cells renew themselves, a finding that advances the quest to expand these cells in the lab for clinical use in bone marrow transplantation, a procedure that saves thousands of lives every year.

26 Aug 2013

Researchers discover additional cystic fibrosis-causing mutations

Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis, it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway in figuring out which mutations are benign and which are deleterious. In so doing, they have increased the number of known CF-causing mutations from 22 to 127, accounting for 95 percent of the variations found in patients with CF.

26 Aug 2013

Scanning technique reveals how brain tumor responds to drug administered

A new scanning technique developed by Danish and US researchers reveals how susceptible patients with aggressive brain cancer are to the drugs they receive. The research behind the ground-breaking technique has just been published in Nature Medicine.

26 Aug 2013

BES procedure may prevent cell apoptosis in stem cell-based transplantation therapy

Researchers at the Beihang University School of Biological Science and Medical Engineering, led by Dr. Yubo Fan, have discovered that Biphasic Electrical stimulation (BES), a non-chemical procedure, may be used as a strategy for preventing cell apoptosis in stem cell-based transplantation therapy.

26 Aug 2013

Early antiretroviral therapy treatment benefits HIV-infected infants

Giving antiretroviral therapy immediately after diagnosis for a limited period of time is more beneficial than postponing treatment in young infants infected with HIV, slowing progression of the disease and delaying the time to starting long-term ART, according to new research published in The Lancet.

23 Aug 2013

Article sheds new light on differences between normal aging and Alzheimer's disease

The ability of different regions of the brain to communicate gradually breaks down with aging and in Alzheimer's disease, but there are key differences between these two processes. Some of these differences are reported in a study that compared neural networks, signaling efficiency, and disruptions in connectivity in the brains of healthy elderly subjects and patients with Alzheimer's disease.

23 Aug 2013

Innovative memory aid system for dementia patients

A NEW ‘home help’ website giving dementia patients timely reminders and reassuring them of key visits of family, relatives, social activities and carers is being trialled in a care home in Sheffield.

23 Aug 2013

Shire extends existing partnership with Santaris Pharma in rare genetic disease space

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, today announced that its long term partner, Shire has extended the existing partnership in the rare genetic disease space.

23 Aug 2013

Tufts Health Plan provides positive coverage decision and in-network provider status to bioTheranostics

bioTheranostics, a leading provider of molecular diagnostic solutions for cancer, has received a positive coverage decision and in-network provider status from Tufts Health Plan for its CancerTYPE ID molecular cancer classifier.

23 Aug 2013

Stem cell therapy improves radiation-induced cognitive impairment

Patients receiving cranial irradiation treatment for brain cancer may find the treatment life-saving, but often suffer progressive and debilitating cognitive detriments, including spatial learning and memory deficits. The cognitive deficits are a contributing factor to the often significant adverse impacts on the surviving patients' quality of life after radiation therapy. In an effort to improve post-irradiation cognitive impairment, scientists at the University of California, Irvine, and colleagues at Neuralstem, Inc. (Rockville, MD), have transplanted fetal stem cells into laboratory animals with radiation-induced cognitive impairments and found that this led to a number of cognitive improvements.

23 Aug 2013

NYU Langone Medical Center announces opening of new wound healing center

NYU Langone Medical Center announces the opening of the new Helen L. and Martin S. Kimmel Hyperbaric and Advanced Wound Healing Center at 240 East 38th Street. One of only two Hyperbaric Centers in Manhattan providing treatment to patients with chronic non-healing wounds, patients now have access to surgical and non-surgical expertise within one location.

23 Aug 2013

New technique may convert cells from heart disease patients into heart muscle cells

Researchers have developed a new technique that might one day be used to convert cells from heart disease patients into heart muscle cells that could act as a personalized treatment for their condition.

23 Aug 2013

MFDCs have advantages over adult skin cells, including proliferation and differentiation

Multipotent fetal dermal cells (MFDCs) may be an ideal source for cell therapy for repairing damaged tissues and organs. Their performance is superior to that of adult dermal cells, said a research team in Italy that developed a cell isolation technique for MFDCs and subsequently published a study that appears as an early e-publication for the journal Cell Transplantation.

23 Aug 2013

New radiation treatment can reduce bone pain, extend lives of prostate cancer patients

Prostate cancer that has spread to the bones can cause pain and fractures. Loyola University Medical Center is among the first hospitals in Chicago to offer a new targeted radiation treatment that can reduce bone pain and the incidence of fractures - and also extend patients' lives.

23 Aug 2013

Seven researchers to receive grants from ASTRO to advance radiation oncology research

The American Society for Radiation Oncology (ASTRO) has selected seven (7) leading researchers who will receive a total of $675,000 in awards and grants to advance radiation oncology research.

23 Aug 2013

Drug to treat blood cancers may also stop spread of invasive breast cancer

A drug used to treat blood cancers may also stop the spread of invasive breast cancer, researchers at Mayo Clinic in Florida have discovered. Their study, published online in Breast Cancer Research, found that in the lab and in animals, the drug decitabine turns on a gene coding for protein kinase D1 (PRKD1) that halts the ability of cancer cells to separate from a tumor and spread to distant organs.

23 Aug 2013

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Variants in a particular gene are linked with an increased risk for kidney complications in patients with lupus, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings could lead to better treatments to protect the kidney health of patients with the disease.

23 Aug 2013

Noninvasive urine test can accurately monitor risk of kidney rejection

Levels of a protein in the urine of kidney transplant recipients can distinguish those at low risk of developing kidney injury from those at high risk, a study suggests. The results also suggest that low levels of this protein, called CXCL9, can rule out rejection as a cause of kidney injury.

23 Aug 2013

Therapy News and Research

FDA grants marketing approval for VALCHLOR gel for treatment of early stage CTCL

Mayo Clinic opens its own stem cell laboratory in summer 2014

Scientists discover mechanisms of GATA3 gene that govern blood stem cell self-renewal process

Researchers discover additional cystic fibrosis-causing mutations

Scanning technique reveals how brain tumor responds to drug administered

BES procedure may prevent cell apoptosis in stem cell-based transplantation therapy

Early antiretroviral therapy treatment benefits HIV-infected infants

Article sheds new light on differences between normal aging and Alzheimer's disease

Innovative memory aid system for dementia patients

Shire extends existing partnership with Santaris Pharma in rare genetic disease space

Tufts Health Plan provides positive coverage decision and in-network provider status to bioTheranostics

Stem cell therapy improves radiation-induced cognitive impairment

NYU Langone Medical Center announces opening of new wound healing center

New technique may convert cells from heart disease patients into heart muscle cells

MFDCs have advantages over adult skin cells, including proliferation and differentiation

New radiation treatment can reduce bone pain, extend lives of prostate cancer patients

Seven researchers to receive grants from ASTRO to advance radiation oncology research

Drug to treat blood cancers may also stop spread of invasive breast cancer

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Noninvasive urine test can accurately monitor risk of kidney rejection

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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