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NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy

A team of NUS researchers from the Departments of Bioengineering and Orthopaedic Surgery has developed a highly realistic three-dimensional (3-D) tumour model. As it replicates the conditions in the body, it is able to track the effectiveness and progress of drug therapy.

20 Jun 2013

EORTC starts phase 2 trial in elderly patients with HER-2 positive metastatic breast cancer

Despite the fact that the incidence of cancer is many fold higher in persons over 65 years of age, we still have an inadequate understanding on how best to treat these older cancer patients. Furthermore, even though elderly patients are occasionally included in clinical trials, those elderly patients who are eventually included are mostly 'healthy' (fit) elderly patients.

20 Jun 2013

Treating bacteria with silver compounds boosts efficacy of old antibiotics

Slipping bacteria some silver could give old antibiotics new life, scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University reported June 19 in Science Translational Medicine.

20 Jun 2013

Updated guidelines on diagnosis and management of osteoporosis published in Maturitas

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today the publication of the National Osteoporosis Guideline Group Update 2013 on diagnosis and management of osteoporosis in postmenopausal women and older men in the journal Maturitas.

20 Jun 2013

British post-menopausal women less likely to access appropriate treatment for vaginal atrophy

New data, published today in Menopause International, suggests that post-menopausal women in Britain are experiencing less sex, and less satisfying sex compared to their European and North American counterparts1, because they are considerably less likely to access appropriate treatment for a common, taboo condition called vaginal atrophy1.

20 Jun 2013

Ibrutinib shows remarkable promise for treatment of mantle cell lymphoma

In a major international study led by researchers at The University of Texas MD Anderson Cancer Center, the targeted therapy ibrutinib continues to show remarkable promise for the treatment of relapsed or refractory mantle cell lymphoma (MCL).

20 Jun 2013

Researchers develop method to identify aggressive prostate cancers

Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms. The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment.

20 Jun 2013

Loyola researcher to study role of Vitamin D in women with diabetes and depression

A Loyola University Chicago Niehoff School of Nursing researcher has received a four-year, $1.49 million grant to study whether Vitamin D can improve mood in women with diabetes who are depressed.

20 Jun 2013

LDL cholesterol blood levels: an interview with Dr. Harvey Kaufman

What is LDL cholesterol? What blood level of LDL cholesterol is considered optimal and why are high levels of LDL cholesterol a key marker of death risk from heart disease? Dr. Harvey Kaufman, senior medical director of Quest Diagnostics gives us some answers.

From Quest Diagnostics 19 Jun 2013

Study describes molecular bases of resistance to new chemotherapeutic agent in familial breast and ovarian cancers

It is estimated that between 5% and 10% of breast and ovarian cancers are familial in origin, which is to say that these tumours are attributable to inherited mutations from the parents in genes such as BRCA1 or BRCA2.

19 Jun 2013

SimuCase avatars allow graduate students to evaluate speech-language disorders

A new commercial venture, using technology developed at Case Western Reserve University's College of Arts and Sciences and Case School of Engineering, has made available avatars-virtual patients-to train speech-language pathologists.

19 Jun 2013

Insulin degludec has reduced risk of recurrent hypoglycemia than insulin glargine

Insulin degludec (Tresiba), a new ultra-long-acting insulin, has a similar or reduced risk of recurrent hypoglycemia—low blood sugar—compared with the commercially available insulin glargine, a new meta-analysis study finds.

19 Jun 2013

AACE applauds the American Medical Association for recognizing obesity as disease state

The American Association of Clinical Endocrinologists (AACE) applauds the American Medical Association (AMA) House of Delegates for its action today to approve a resolution recognizing obesity as a disease state requiring a range of interventions to advance obesity treatment and prevention. AACE, the sponsor of the resolution, was joined by specialty and state medical societies in advocating for recognition of obesity as a disease state, including The Endocrine Society, American College of Cardiology, American College of Surgeons, American Urological Association, and the Texas State Delegation among many others.

19 Jun 2013

Thrombolytic treatment after stroke associated with reduced in-hospital mortality

In a study that included nearly 60,000 patients with acute ischemic stroke, thrombolytic treatment (to help dissolve a blood clot) that was started more rapidly after symptom onset was associated with reduced in-hospital mortality and intracranial hemorrhage and higher rates of independent walking ability at discharge and discharge to home, according to a study in the June 19 issue of JAMA.

19 Jun 2013

Psychologists must be educated to treat sexual minority youth

President Obama officially declared June as Lesbian, Gay, Bisexual and Transgender (LGBT) Pride Month. However, despite advances in civil rights, sexual minority youth are still at greater risk for suicide than their heterosexual peers, according to the Suicide Prevention Resource Center.

19 Jun 2013

Ico Therapeutics completes Phase 2 iDEAL study for treatment of diabetic macular edema

iCo Therapeutics Inc. announced today that it has completed enrollment of its Phase 2 iDEAL study evaluating the efficacy and safety after repeated injections of iCo-007 in patients with Diabetic Macular Edema (DME). The study has shown a good safety profile with no drug-related serious adverse events to date.

19 Jun 2013

Journal of Bone and Joint Surgery reveals important trends and changes in orthopaedic practice

Data from the recent release from The Journal of Bone and Joint Surgery, The Third Annual Role of the Orthopaedic Surgeon Study 2013, reveals important trends in the ways that orthopaedic practice is changing in the face of significant increases in hospital-owned practices, cost pressures, and regulations.

19 Jun 2013

State highlights: Texas pharmacists want Medicaid price transparency

Pennsylvania is joining about 20 other states in limiting coverage of abortions under health care insurance policies offered in a federally-run insurance marketplace starting next year under a sweeping federal law. The office of Gov. Tom Corbett, a Republican who opposes abortion rights, said he signed the bill Monday, without offering any comment (6/17).

19 Jun 2013

Report examines Medicare spending issues, geographic disparities and hospital payments

The report from the congressional advisory group MedPAC assesses a variety of issues, including penalties that Medicare has recently begun imposing on hospitals and how that affects facilities largely serving poor patients.

18 Jun 2013

Scientists discover new anti-tuberculosis compound that kills drug-resistant TB bacteria

An international team led by scientists at The Scripps Research Institute (TSRI), the Howard Hughes Medical Institute and Albert Einstein College of Medicine of Yeshiva University has identified a highly promising new anti-tuberculosis compound that attacks the tuberculosis (TB) bacterium in two different ways.

18 Jun 2013

Therapy News and Research

NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy

EORTC starts phase 2 trial in elderly patients with HER-2 positive metastatic breast cancer

Treating bacteria with silver compounds boosts efficacy of old antibiotics

Updated guidelines on diagnosis and management of osteoporosis published in Maturitas

British post-menopausal women less likely to access appropriate treatment for vaginal atrophy

Ibrutinib shows remarkable promise for treatment of mantle cell lymphoma

Researchers develop method to identify aggressive prostate cancers

Loyola researcher to study role of Vitamin D in women with diabetes and depression

LDL cholesterol blood levels: an interview with Dr. Harvey Kaufman

Study describes molecular bases of resistance to new chemotherapeutic agent in familial breast and ovarian cancers

SimuCase avatars allow graduate students to evaluate speech-language disorders

Insulin degludec has reduced risk of recurrent hypoglycemia than insulin glargine

AACE applauds the American Medical Association for recognizing obesity as disease state

Thrombolytic treatment after stroke associated with reduced in-hospital mortality

Psychologists must be educated to treat sexual minority youth

Ico Therapeutics completes Phase 2 iDEAL study for treatment of diabetic macular edema

Journal of Bone and Joint Surgery reveals important trends and changes in orthopaedic practice

State highlights: Texas pharmacists want Medicaid price transparency

Report examines Medicare spending issues, geographic disparities and hospital payments

Scientists discover new anti-tuberculosis compound that kills drug-resistant TB bacteria

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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