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Hormone treatment to halt puberty in transgender adolescents is safe and effective

Hormone treatment to halt puberty in adolescents with gender identity disorder does not cause lasting harm to their bones, a new study finds. The results were presented today at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

OncoSec Medical completes enrollment in ImmunoPulse trial for metastatic melanoma patients

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumor cancers, announced the completion of patient enrollment in a Phase II clinical trial of ImmunoPulse for metastatic melanoma patients.

18 Jun 2013

DTE from animal thyroid glands is a safe alternative to T4 therapy in hypothyroid patients

Desiccated thyroid extract (DTE), derived from crushed preparations of animal thyroid glands, is a safe and effective alternative to standard T4 therapy in hypothyroid patients, a new study finds. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Combination of obesity and low testosterone increases risk of diabetes and brain damage

Low testosterone worsens the harmful effects of obesity in the nervous system, a new study in mice finds. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Genomic instability in new molecular pathway may predict worse outcomes in breast cancer patients

A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

18 Jun 2013

Estrogen replacement therapy reduces anxiety symptoms in girls with anorexia nervosa

Estrogen replacement therapy is associated with a significant decrease in anxiety symptoms among girls with anorexia nervosa, a new clinical trial finds. The results will be presented today at The Endocrine Society's Annual Meeting in San Francisco.

18 Jun 2013

Study: Whole body vibration therapy raises bone strength among adolescents with cerebral palsy

A treatment known as whole body vibration therapy significantly increases bone strength among adolescents with cerebral palsy, a new clinical trial from New Zealand shows. The results were presented Saturday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Women with polycystic ovary syndrome lose more weight when they take two drugs

Women with polycystic ovary syndrome, or PCOS, lost significantly more weight when they took two drugs that are traditionally used to treat diabetes, rather than either drug alone, a study from Slovenia demonstrates. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

State highlights: States urge using life insurance for long-term care

State lawmakers are encouraging elderly residents to use life insurance as a way to pay for long-term care -- and lower the Medicaid tab in the process. The strategy marks a tacit endorsement of so-called life settlements, a practice in which policyholders sell their policies at a discount in the secondary market and the buyer takes over premiums and consequently collects the death benefit (Greene, 6/16).

18 Jun 2013

Vercise DBS System shows improvement in motor scores for patients with Parkinson's disease

Patients with Parkinson's disease using the Boston Scientific Corporation Vercise DBS (deep brain stimulation) System showed a significant improvement in motor scores according to interim data from the VANTAGE DBS study.

18 Jun 2013

TWi Biotechnology completes patient enrollment in phase II trial of AC-201 for Gout Flare Prophylaxis

TWi Biotechnology, Inc. announced that it has completed the patient enrollment in a phase II trial of AC-201 for Gout Flare Prophylaxis during urate-lowering therapy. This randomized, double-blind, placebo-controlled Phase II study is conducted in 8 major medical centers in Taiwan.

18 Jun 2013

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

Vanda Pharmaceuticals Inc. presented additional data today at ENDO 2013, the Endocrine Society's 95th Annual Meeting, demonstrating that tasimelteon can entrain (synchronize) both melatonin and cortisol rhythms.

18 Jun 2013

Santarus, Pharming Group announce FDA acceptance of RUCONEST BLA

Santarus, Inc. and Pharming Group NV today announced that the U.S. Food and Drug Administration has accepted for filing the Biologics License Application for the investigational drug RUCONEST (recombinant human C1 esterase inhibitor) 50 IU/kg.

18 Jun 2013

Researchers use patient-specific stem cells to correct deficient insulin-producing cells

A team from the New York Stem Cell Foundation Research Institute and the Naomi Berrie Diabetes Center of Columbia University has generated patient-specific beta cells, or insulin-producing cells, that accurately reflect the features of maturity-onset diabetes of the young.

18 Jun 2013

Age disparities exist in continuum of care for patients with HIV

Age disparities exist in the continuum of care for patients with the human immunodeficiency virus (HIV) with people younger than 45 years less likely to be aware of their infection or to have a suppressed viral load, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

18 Jun 2013

Mannitol could prevent aggregation of toxic proteins in the brain, says Tel Aviv University researcher

Mannitol, a sugar alcohol produced by fungi, bacteria, and algae, is a common component of sugar-free gum and candy. The sweetener is also used in the medical field - it's approved by the FDA as a diuretic to flush out excess fluids and used during surgery as a substance that opens the blood/brain barrier to ease the passage of other drugs.

18 Jun 2013

Pyrvinium pamoate inhibits drug-resistant prostate cancer

A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

TSRI scientists identify highly promising new anti-tuberculosis compound

An international team led by scientists at The Scripps Research Institute, the Howard Hughes Medical Institute and Albert Einstein College of Medicine of Yeshiva University has identified a highly promising new anti-tuberculosis compound that attacks the tuberculosis bacterium in two different ways.

18 Jun 2013

Men with low-risk prostate cancers can choose watchful waiting for better quality of life, study says

Many men with low-risk, localized prostate cancers can safely choose active surveillance or "watchful waiting" instead of undergoing immediate treatment and have better quality of life while reducing health care costs, according to a study by researchers at Dana-Farber Cancer Institute and Massachusetts General Hospital.

18 Jun 2013

Bazedoxifene used for treating osteoporosis stops growth of breast cancer cells

A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study.

17 Jun 2013

Therapy News and Research

Hormone treatment to halt puberty in transgender adolescents is safe and effective

OncoSec Medical completes enrollment in ImmunoPulse trial for metastatic melanoma patients

DTE from animal thyroid glands is a safe alternative to T4 therapy in hypothyroid patients

Combination of obesity and low testosterone increases risk of diabetes and brain damage

Genomic instability in new molecular pathway may predict worse outcomes in breast cancer patients

Estrogen replacement therapy reduces anxiety symptoms in girls with anorexia nervosa

Study: Whole body vibration therapy raises bone strength among adolescents with cerebral palsy

Women with polycystic ovary syndrome lose more weight when they take two drugs

State highlights: States urge using life insurance for long-term care

Vercise DBS System shows improvement in motor scores for patients with Parkinson's disease

TWi Biotechnology completes patient enrollment in phase II trial of AC-201 for Gout Flare Prophylaxis

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

Santarus, Pharming Group announce FDA acceptance of RUCONEST BLA

Researchers use patient-specific stem cells to correct deficient insulin-producing cells

Age disparities exist in continuum of care for patients with HIV

Mannitol could prevent aggregation of toxic proteins in the brain, says Tel Aviv University researcher

Pyrvinium pamoate inhibits drug-resistant prostate cancer

TSRI scientists identify highly promising new anti-tuberculosis compound

Men with low-risk prostate cancers can choose watchful waiting for better quality of life, study says

Bazedoxifene used for treating osteoporosis stops growth of breast cancer cells

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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