Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Researchers unravel mechanisms that enable accumulation of tumour promoting protease in stressed cancer cells

A mechanism beyond the level of gene regulation, which is often the underlying reason for changes in protein levels, does enable the strong accumulation of a tumour promoting protease in stressed cancer cells. The group of BIOSS researcher Prof. Dr. Thomas Reinheckel teamed up with BIOSS investigator Prof. Dr. Sabine Rospert and their colleagues from the University Medical Center Freiburg, Prof. Dr. Elmar Stickeler and Dr. Peter Bronsert, in order to unravel mechanisms by which stress-resistant production of cancer promoting proteins occurs.

6 Jul 2015

Imaging proteasome complex helps show target site for potential cancer drugs

Scientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life - a cellular recycling unit with a role in many diseases.

3 Jul 2015

Researchers discover link between acute liver failure and specific gene mutations in young children

Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent of cases it is unclear as to why this happens. Now, a team of researchers working on an international research project headed by Technische Universität München, the Helmholtz Zentrum Munich and Heidelberg University Hospital have discovered a link between the disease and mutations in a specific gene.

3 Jul 2015

Researchers establish link between NBAS gene and acute liver failure

Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent of cases it is unclear as to why this happens. Now, a team of researchers working on an international research project headed by Technische Universität München (TUM), the Helmholtz Zentrum Munich and Heidelberg University Hospital have discovered a link between the disease and mutations in a specific gene.

2 Jul 2015

Scientists identify mechanism that reveals why stem cells undergo self-renewing divisions

UT Southwestern Medical Center scientists collaborating with University of Michigan researchers have found a previously unidentified mechanism that helps explain why stem cells undergo self-renewing divisions but their offspring do not.

2 Jul 2015

UTHealth researchers discover new light-activated proteins that work as 'off switches' for brain cells

Light switches for neurons have made enormous contributions to brain research by giving investigators access to "on switches" for brain cells. But, finding "off switches" has been much more challenging.

2 Jul 2015

Special issue provides comprehensive overview of latest findings in the area of skeletal research

While there is good understanding of how bone mass, and more recently bone architecture, affects fracture risk, far less is known about the material properties of bone, or how these can impart resilience or fragility to the skeleton.

2 Jul 2015

Certain stem cells use microscopic nanotubes to communicate with neighboring cells, shows research

When it comes to communicating with each other, some cells may be more "old school" than was previously thought. Certain types of stem cells use microscopic, threadlike nanotubes to communicate with neighboring cells, like a landline phone connection, rather than sending a broadcast signal, researchers at University of Michigan Life Sciences Institute and University of Texas Southwestern Medical Center have discovered.

2 Jul 2015

Lucideon welcomes students on 7th framework European project ‘Biodensol’

Lucideon, the international materials technology company, welcomes three international students on the 7th framework European project ‘Biodensol’. The three students involved with the project have now begun an intense training period before they embark on developing novel glass, ceramic and sol-gel powders with dental applications.

From Lucideon 1 Jul 2015

smFRET method takes measurements of distances between molecules

Have a look round your living room. Everything around you is made up of molecules - just as you are. When they are put together, the molecules act as the building blocks of life.

1 Jul 2015

New species of tRNA-derived small RNAs contribute to cell proliferation in cancer

Since their discovery in the 1950s, transfer RNAs (tRNAs) have been best known for their role in helping the cell make proteins from messenger RNA templates. However, recent studies have led to a previously-unsuspected concept that tRNAs are not always the end product; namely, they further serve as a source of small RNAs.

30 Jun 2015

Scientists develop high-throughput strategy to build de novo genomes

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new approach to build nearly complete genomes by combining high-throughput DNA sequencing with genome mapping. The methodology enabled researchers to detect complex forms of genomic variation, critically important for their association with human disease, but previously difficult to detect.

30 Jun 2015

Elsevier announces highlights of 2014 Impact Factor performance

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the highlights of its journal Impact Factor performance in 2014. According to the 2014 Journal Citation Reports (JCR) published by Thomson Reuters, Elsevier saw 55% of its journal Impact Factors increase from 2013 to 2014, ahead of the aggregate across other journals.

29 Jun 2015

Special protein in the brain's smallest blood vessels may affect stroke risk

Studies on mice reveal that a special protein in the brain's tiniest blood vessels may affect the risk of stroke. Peter Carlsson, professor in genetics at the University of Gothenburg, and his research team are publishing new research findings in the journal Developmental Cell about how the blood-brain barrier develops and what makes the capillaries in the brain different from small blood vessels in other organs.

26 Jun 2015

Biontech, Siemens enter into strategic collaboration on manufacture of personalized cancer vaccines

Siemens and BioNTech AG, a fully integrated biotechnology company developing truly personalized cancer immunotherapies, have entered into a strategic collaboration.

25 Jun 2015

Umeå University to present special Jubilee Award to Emmanuelle Charpentier at Annual Celebration Ceremony

Umeå University honours Professor Emmanuelle Charpentier for her pioneering research with the powerful discovery of CRISPR-Cas9, which has already been of great importance by providing new opportunities for Life Science research and its applications in Biology and Medicine. Umeå University will present a special Jubilee Award to Emmanuelle Charpentier

25 Jun 2015

Sanford-Burnham gets $100 million gift from Conrad Prebys

Sanford-Burnham Medical Research Institute (Sanford-Burnham) announced today that it has received a gift of $100 million from prominent San Diego developer, philanthropist, and Sanford-Burnham honorary trustee Conrad Prebys.

24 Jun 2015

UMass Amherst reports how two molecular pathways get together to ensure normal bacterial growth

As part of their long-term investigation of regulatory factors in the bacterial cell cycle, molecular biologists at the University of Massachusetts Amherst now report finding a surprising new role for one factor, CpdR, an adaptor that helps to regulate selective protein destruction, the main control mechanism of cell cycle progression in bacteria, at specific times.

23 Jun 2015

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

A promising biomarker for the severity of age-related white matter changes (ARWMCs) and endothelial function was evaluated at Hiroshima University, Japan. The relationship between this biomarker, the telomeric 3'-overhang (G-tail) length, and cardiovascular risk in humans is unclear so far.

23 Jun 2015

Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

One of the body's tools for fighting off infection in a wound may actually slow down the healing process, according to new research by a team of Harvard University, Boston Children's Hospital, and Penn State University scientists.

19 Jun 2015

Molecular Biology News and Research

Further Reading

Researchers unravel mechanisms that enable accumulation of tumour promoting protease in stressed cancer cells

Imaging proteasome complex helps show target site for potential cancer drugs

Researchers discover link between acute liver failure and specific gene mutations in young children

Researchers establish link between NBAS gene and acute liver failure

Scientists identify mechanism that reveals why stem cells undergo self-renewing divisions

UTHealth researchers discover new light-activated proteins that work as 'off switches' for brain cells

Special issue provides comprehensive overview of latest findings in the area of skeletal research

Certain stem cells use microscopic nanotubes to communicate with neighboring cells, shows research

Lucideon welcomes students on 7th framework European project ‘Biodensol’

smFRET method takes measurements of distances between molecules

New species of tRNA-derived small RNAs contribute to cell proliferation in cancer

Scientists develop high-throughput strategy to build de novo genomes

Elsevier announces highlights of 2014 Impact Factor performance

Special protein in the brain's smallest blood vessels may affect stroke risk

Biontech, Siemens enter into strategic collaboration on manufacture of personalized cancer vaccines

Umeå University to present special Jubilee Award to Emmanuelle Charpentier at Annual Celebration Ceremony

Sanford-Burnham gets $100 million gift from Conrad Prebys

UMass Amherst reports how two molecular pathways get together to ensure normal bacterial growth

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

Preventing neutrophils from producing NETs can accelerate wound healing in diabetic mice

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