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Disparities in access to novel infusion treatment for Alzheimer's disease revealed

Adoption of lecanemab, a novel infusion treatment for Alzheimer's disease (AD), has been disproportionately higher among patients who are male, white, from urban areas, and have higher socioeconomic status, new research suggests.

15 May 2025

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular nanostructures and demonstrated these TPAs can inhibit amyloid beta aggregation. In vitro, TPAs significantly improved survival of human neurons exposed to amyloid-induced neurotoxicity, suggesting therapeutic potential for neurodegenerative diseases.

15 May 2025

$Testosterone gel fails to boost recovery after hip fracture in women$

Testosterone gel fails to boost recovery after hip fracture in women

Hip fractures, often a result of a fall, are the most serious type of osteoporotic fracture because they are accompanied by considerable pain, loss of muscle and bone strength, reduced mobility and independence with daily activities, and increased risk for future fractures and death.

15 May 2025

New gene editor evoCAST enables precise insertion of complete genes

Ask scientists what gene editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of Physicians and Surgeons and David Liu at the Broad Institute of MIT and Harvard.

15 May 2025

Study links long COVID brain fog to inflammation and stress markers

A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.

15 May 2025

Study finds fewer H. pylori infections among Parkinson’s patients

A large case-control study from China found that people with Parkinson’s disease were significantly less likely to test positive for Helicobacter pylori infection compared to controls. The findings suggest a potential protective link between this common stomach bacterium and Parkinson’s disease, though causality remains unproven.

15 May 2025

Customized CRISPR gene editing therapy successfully treats infant with rare disease

In a historic medical breakthrough, a child diagnosed with a rare genetic disorder has been successfully treated with a customized CRISPR gene editing therapy by a team at Children's Hospital of Philadelphia (CHOP) and Penn Medicine.

15 May 2025

TMEM219 inhibition shows promise in restoring intestinal health in IBD

An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death receptor TMEM219 to restore mucosal healing in inflammatory bowel diseases.

15 May 2025

Shorter radiation treatment after surgery found safe for prostate cancer patients

For men who undergo a radical prostatectomy for the treatment of prostate cancer, post-surgery radiation therapy can play a vital role in reducing the risk of recurrence.

15 May 2025

Older adults in sub-Saharan Africa face growing HIV epidemic

Prevention and treatment campaigns are not adequately targeting the particular needs of the 50+ years age group.

15 May 2025

Physical function before treatment predicts response to daratumumab in multiple myeloma

How cancer patients relying on daratumumab feel physically before starting the therapy can predict how long they will live and how well they will respond to the anti- multiple myeloma (MM) drug, according to a new study published in the European Journal of Haematology.

14 May 2025

AAN releases Evidence in Focus Article on new gene therapy for Duchenne muscular dystrophy

To help neurologists, clinicians and families understand the current evidence for a new gene therapy for Duchenne muscular dystrophy called delandistrogene moxeparvovec, the American Academy of Neurology (AAN) has issued an Evidence in Focus article, published May 14, 2025, online in Neurology.

14 May 2025

Loss of drug subsidies linked to higher mortality among low-income Medicare beneficiaries

While it may seem intuitive that people would die without life-saving medications, Penn and Harvard researchers have connected losing a federally funded prescription drug assistance program and an increase in mortality.

14 May 2025

Mindfulness-based therapy offers new hope for people with persistent depression

Mindfulness-based therapy can offer significant relief for individuals who are still depressed after receiving treatment, according to a new clinical trial.

14 May 2025

Injecting medicine into amniotic fluid shows promise for treating genetic disorders

Injecting medicine into the amniotic fluid staves off progression of spinal muscular atrophy in utero.

14 May 2025

Novel nanoparticle could make ultrasound-based cancer treatments more effective and safer

Researchers have created a new kind of nanoparticle that could make ultrasound-based cancer treatments more effective and safer, while also helping prevent tumors from coming back.

14 May 2025

GLP-1 weight loss drugs leave users low on key nutrients, study finds

This study assessed nutrient intake in adults using GLP-1 receptor agonists (GLP-1RAs) and found widespread deficiencies in essential vitamins and minerals. Despite appetite suppression and weight loss benefits, most participants exceeded fat intake recommendations and failed to meet protein and micronutrient needs.

14 May 2025

New approach directly combats the progression of Alzheimer’s and ALS

Scientists at Northwestern University have developed a new approach that directly combats the progression of neurodegenerative diseases like Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

14 May 2025

Cubic successfully showcased complete industry sensing solutions at SENSOR+TEST exhibition

Cubic has successfully exhibited its latest innovations at SENSOR+TEST 2025 international trade fair, showcasing how its smart technologies and sensing solutions empower the six key application fields, including oil & gas, semiconductor manufacturing, medical & healthcare, automotive electronics, HVAC & refrigeration, and heating boiler & furnace.

From Cubic Sensor and Instrument Co. Ltd 14 May 2025

Skin microbiome plays active role in sun protection and immune balance

The skin microbiome plays an important role in health and disease. Researchers have now substantiated that certain skin bacteria can protect us from the sun's ultraviolet (UV) radiation specifically by metabolizing cis-urocanic acid using an enzyme called urocanase.

13 May 2025

Therapy News and Research

Disparities in access to novel infusion treatment for Alzheimer's disease revealed

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Testosterone gel fails to boost recovery after hip fracture in women

New gene editor evoCAST enables precise insertion of complete genes

Study links long COVID brain fog to inflammation and stress markers

Study finds fewer H. pylori infections among Parkinson’s patients

Customized CRISPR gene editing therapy successfully treats infant with rare disease

TMEM219 inhibition shows promise in restoring intestinal health in IBD

Shorter radiation treatment after surgery found safe for prostate cancer patients

Older adults in sub-Saharan Africa face growing HIV epidemic

Physical function before treatment predicts response to daratumumab in multiple myeloma

AAN releases Evidence in Focus Article on new gene therapy for Duchenne muscular dystrophy

Loss of drug subsidies linked to higher mortality among low-income Medicare beneficiaries

Mindfulness-based therapy offers new hope for people with persistent depression

Injecting medicine into amniotic fluid shows promise for treating genetic disorders

Novel nanoparticle could make ultrasound-based cancer treatments more effective and safer

GLP-1 weight loss drugs leave users low on key nutrients, study finds

New approach directly combats the progression of Alzheimer’s and ALS

Cubic successfully showcased complete industry sensing solutions at SENSOR+TEST exhibition

Skin microbiome plays active role in sun protection and immune balance

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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