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CHOP researchers advance stem cell studies in childhood leukemia, Diamond Blackfan anemia

First produced only in the past decade, human induced pluripotent stem cells are capable of developing into many or even all human cell types. In new research, scientists reprogrammed skin cells from patients with rare blood disorders into iPSCs, highlighting the great promise of these cells in advancing understanding of those challenging diseases-and eventually in treating them.

31 Jul 2013

Researchers reveal how SMIP004 anticancer compound targets prostate cancer cells

One major hallmark of cancer cells is their ability to survive under stressful conditions. A new study spearheaded by researchers at Sanford-Burnham Medical Research Institute reveals how a promising anticancer compound called SMIP004 specifically kills prostate cancer cells by compromising their ability to withstand environmental stress.

31 Jul 2013

Researchers secure $16 million NIH grant to investigate impact of HIV/AIDS on women

Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center today announced they received a $16 million grant from the National Institutes of Health to investigate the impact of HIV and AIDS on women.

31 Jul 2013

Baxter, JW Holdings sign distribution, license agreement for omega 3 parenteral nutrition products

Baxter International Inc. and JW Holdings today announced that they have entered into an exclusive distribution and license agreement for parenteral nutritional products containing a novel formulation of omega 3 lipids.

From Baxter International Inc. 31 Jul 2013

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Patients with melanoma brain metastases can be treated with large doses of interleukin-2

In a retrospective study, Saint Louis University researchers have found that patients with melanoma brain metastases can be treated with large doses of interleukin-2 (HD IL-2), a therapy that triggers the body's own immune system to destroy the cancer cells.

31 Jul 2013

Inhalable gene therapy may restore function of crucial enzyme to reverse deadly PAH

The deadly condition known as pulmonary arterial hypertension (PAH), which afflicts up to 150,000 Americans each year, may be reversible by using an inhalable gene therapy, report an international team of researchers led by investigators at the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

31 Jul 2013

Research show online psychotherapy and face-to-face therapy are equally effective

Does psychotherapy via the Internet work? For the first time, clinical researchers from the University of Zurich have studied whether online psychotherapy and conventional face-to-face therapy are equally effective in experiments.

31 Jul 2013

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

With oral anticoagulant rivaroxaban set to be subsidised under the Pharmaceutical Benefits Scheme (PBS) for preventing stroke, NPS MedicineWise is urging people to talk to their doctor before stopping or making any changes to their anticoagulant medicines.

30 Jul 2013

Study shows many parents don't fully understand the finer details of biobank storage

Researchers who collect genetic samples from children for medical research need to explain the process more clearly to parents, according to a new study that suggests many parents don't fully understand the finer details about how these samples will be used and stored. The study was published in June in Genetics in Medicine.

30 Jul 2013

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Genotype 1 is, worldwide, the most prevalent genotype of the hepatitis C virus. It accounts for around seventy percent of all hepatitis C infections.

30 Jul 2013

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

Call it therapeutic poop, if you will, but the best hope yet for an effective treatment of childhood infections with the drug-resistant bacterium C. difficile may come straight from the gut, according to recent research.

30 Jul 2013

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Rebiotix Inc. announced today that the U.S. Food and Drug Administration has approved the company's Investigational New Drug application to begin the Phase 2 clinical study of RBX2660 for the treatment of recurrent Clostridium difficile infection.

30 Jul 2013

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

The USPSTF agreed with the CDC that since most patients (75%) who are currently infected with hepatitis C were born between 1945 - 1965, and since risk-based screening has not been successful in identifying these individuals, that a one time age-based hepatitis C blood test was necessary.

29 Jul 2013

Prana announces dosing of first patient in PBT2 Phase II trial for Alzheimer’s disease

Prana Biotechnology today announced that the first patient has been dosed in the 12-month open label extension study with Alzheimer’s Disease patients participating in Prana’s Phase 2 IMAGINE trial.

29 Jul 2013

Trovagene adopts RainDance's RainDrop digital PCR system for eventual use in CLIA laboratory

Trovagene, Inc. (NASDAQ: TROV) and RainDance Technologies announced today that Trovagene has adopted RainDance's RainDropTM Digital PCR System for research and development, and for eventual use in the Trovagene CLIA laboratory.

29 Jul 2013

ALCF honors oncologist with Lectureship Award for ground-breaking work on lung cancer research

The Bonnie J. Addario Lung Cancer Foundation (ALCF) honored Tony Mok, MD, with the 2013 Addario Lectureship Award for his continued ground-breaking work for lung cancer patients, doctors and caregivers around the world. Dr. Mok, of Chinese University of Hong Kong, received the award at the 14th International Lung Cancer Congress held on July 25 in Huntington Beach, California.

29 Jul 2013

Hepatocytes from stem-cell derived human liver cells increase survival of animals with liver disease

Researchers have generated functional hepatocytes from human stem cells, transplanted them into mice with acute liver injury, and shown the ability of these stem-cell derived human liver cells to function normally and increase survival of the treated animals.

29 Jul 2013

Many women die due to Cad, yet less likely to receive preventive recommendations

Despite coronary artery disease (CAD) killing at least as many women as men each year, women are still today less likely to receive preventive recommendations, such as lipid-lowering therapy, aspirin, and lifestyle advice, than are men at a similar risk level.

29 Jul 2013

Technique for developing more targeted drugs using molecular "robots"

Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a technique for developing more targeted drugs, by using molecular "robots" to hone in on more specific populations of cells.

29 Jul 2013

Therapy News and Research

CHOP researchers advance stem cell studies in childhood leukemia, Diamond Blackfan anemia

Researchers reveal how SMIP004 anticancer compound targets prostate cancer cells

Researchers secure $16 million NIH grant to investigate impact of HIV/AIDS on women

Baxter, JW Holdings sign distribution, license agreement for omega 3 parenteral nutrition products

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

Patients with melanoma brain metastases can be treated with large doses of interleukin-2

Inhalable gene therapy may restore function of crucial enzyme to reverse deadly PAH

Research show online psychotherapy and face-to-face therapy are equally effective

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

Study shows many parents don't fully understand the finer details of biobank storage

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

Prana announces dosing of first patient in PBT2 Phase II trial for Alzheimer’s disease

Trovagene adopts RainDance's RainDrop digital PCR system for eventual use in CLIA laboratory

ALCF honors oncologist with Lectureship Award for ground-breaking work on lung cancer research

Hepatocytes from stem-cell derived human liver cells increase survival of animals with liver disease

Many women die due to Cad, yet less likely to receive preventive recommendations

Technique for developing more targeted drugs using molecular "robots"

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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