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Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

In the largest-ever genetic study of dementia in people of African ancestry, VA researchers identified several genetic risks different from those seen in people of European ancestry.

22 Dec 2022

Radiation damage to mature sperm cannot be repaired and is instead passed on to the offspring

Whether radiation exposure of fathers can have consequences on their children is one of the most long-standing questions in radiation biology.

21 Dec 2022

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

Huge multi-omic data analysis deciphers colorectal cancer genetics

An analysis of more than 100,000 colorectal cancer cases and 154,000 healthy controls published in Nature Genetics uncovered hundreds of signals that may serve as new treatment and prevention targets.

21 Dec 2022

Findings on the origins of the SARS-CoV-2 variant Omicron retracted

On December 1, Charité – Universitätsmedizin Berlin reported new findings on the origins of the SARS-CoV-2 variant Omicron.

20 Dec 2022

Research estimates the evolutionary origins of functional human microgenes

Modern humans evolutionarily split from our chimpanzee ancestors nearly 7 million years ago, yet we are continuing to evolve.

20 Dec 2022

Analysis finds more than 100 new genetic risk factors strongly linked to colorectal cancer

A comprehensive analysis of more than 100,000 colorectal cancer (CRC) cases, led by researchers at the Fred Hutchinson Cancer Center in Seattle and 200 scientific collaborators worldwide, has identified more than 100 new genetic risk factors strongly linked with the disease.

20 Dec 2022

Mild bee venom appears to be more usable for pharmacology

Honeybee venom has been used in traditional medicine for centuries as an anti-inflammatory. Only its main component, melittin, has been scientifically well researched.

20 Dec 2022

MGI’s DNBSEQ-T7* facilitates ultra-deep sequencing of high-complexity metagenomic samples

Thanks to high-throughput sequencing technologies, shotgun metagenomic methods were made possible and had effectively transformed microbiology. Today, advances in both short- and long-read technologies are overcoming many of the previous challenges affecting metagenomic profiling, especially of highly complex samples and environment.

From MGI 20 Dec 2022

MGI’s DNBSEQ-T7* recognized for its ultra-high throughput and excellent accuracy

Thanks to high-throughput sequencing technologies, shotgun metagenomic methods were made possible and had effectively transformed microbiology.

19 Dec 2022

New insights into biophysical origins of the genome's organization inside the cell nucleus

A team of scientists has uncovered the physical principles - a series of forces and hydrodynamic flows - that help ensure the proper functioning of life's blueprint.

19 Dec 2022

First cell-type specific multiomic study of the HIV brain

Researchers identify cell-type-specific differences in HIV integration sites in the brain.

19 Dec 2022

Decoding nucleic acid-based drugs and vaccines through SEC-SLS analysis

In this interview, Malvern Panalytical’s Product Technical Specialist, Stefan Cairns, discusses how SEC-SLS can be used to understand MRNA vector composition by referencing his latest publication.

From Malvern Panalytical 19 Dec 2022

Cryo-electron microscopy reveals atomic structure of Staphylococcus epidermidis bacteriophage

Cryo-electron microscopy by University of Alabama at Birmingham researchers has exposed the structure of a bacterial virus with unprecedented detail.

18 Dec 2022

Genome assembly tool could spur the development of new treatments for tuberculosis

Researchers have developed a novel genome assembly tool that could spur the development of new treatments for tuberculosis and other bacterial infections.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus.

16 Dec 2022

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Cleft lip and palate are among the most common congenital malformations, which are mainly due to genetic causes.

16 Dec 2022

Next-generation sequencing could change research on sexual assault cases

In this interview, Alexis Garloff talks to NewsMedical about her next-generation sequencing research and the possible applications in forensics, particularly in sexual assault cases.

From Verogen, Inc. 16 Dec 2022

mRNA vaccine methodologies: Production, value and spectrometer use

To be decided by the editor

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 16 Dec 2022

Genome News and Research

Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

Radiation damage to mature sperm cannot be repaired and is instead passed on to the offspring

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

Huge multi-omic data analysis deciphers colorectal cancer genetics

Findings on the origins of the SARS-CoV-2 variant Omicron retracted

Research estimates the evolutionary origins of functional human microgenes

Analysis finds more than 100 new genetic risk factors strongly linked to colorectal cancer

Mild bee venom appears to be more usable for pharmacology

MGI’s DNBSEQ-T7* facilitates ultra-deep sequencing of high-complexity metagenomic samples

MGI’s DNBSEQ-T7* recognized for its ultra-high throughput and excellent accuracy

New insights into biophysical origins of the genome's organization inside the cell nucleus

First cell-type specific multiomic study of the HIV brain

Decoding nucleic acid-based drugs and vaccines through SEC-SLS analysis

Cryo-electron microscopy reveals atomic structure of Staphylococcus epidermidis bacteriophage

Genome assembly tool could spur the development of new treatments for tuberculosis

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Next-generation sequencing could change research on sexual assault cases

mRNA vaccine methodologies: Production, value and spectrometer use

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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