Placebo News and Research

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One class of diabetes drug not associated with reduced risk of death

One class of drug used to treat type 2 diabetes may not reduce the risk of death when compared with placebo, suggests new findings.

17 Apr 2018

Antioxidant treatment may decrease cardiovascular risk in women with type 1 diabetes

The high estrogen levels that typically afford younger women protection from cardiovascular disease appear to instead multiply their risk if they have type 1 diabetes, researchers say.

17 Apr 2018

Intranasal formulation of ketamine shows promise in rapid treatment of depression, suicidality

A nasal spray formulation of ketamine shows promise in the rapid treatment of symptoms of major depression and suicidal thoughts, according to a new study published online today in The American Journal of Psychiatry.

16 Apr 2018

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Omega-3 supplements found to be ineffective in alleviating dry eye symptoms

More than 16 million Americans suffer from dry eye, an often chronic condition that causes burning, itching, or stinging sensations in the eye, as well as impaired vision.

13 Apr 2018

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure.

13 Apr 2018

Intranasal spray shows promise for peanut allergy suppression

A vaccine delivered in the form of an ultrafine nasal spray has been shown to protect against allergy symptoms peanut sensitive mice.

13 Apr 2018

Ludwig scientists develop and test individualized ovarian cancer vaccine

A Ludwig Cancer Research study has shown that an entirely new type of personalized cancer vaccine induces novel, potent and clinically effective immune responses in patients receiving a combination of standard therapies for recurrent, stage III and IV ovarian cancer.

11 Apr 2018

Review identifies ethical issues in vitamin D research involving use of placebos

Since World War II, medical ethics in research studies involving human subjects have shifted significantly. Despite this important growth, ethical issues remain. Nutrition supplementation research does not have guidelines around the use of placebo groups in clinical trials, posing ethical issues.

6 Apr 2018

Study shows role of benzodiazepines in managing depression

A paper published in the current issue of Psychotherapy and Psychosomatics, as a result of the collaboration of several universities (University of Bologna, The Pennsylvania State University, Wayne State University, University of Pennsylvania) points to the important role that benzodiazepines may have in depression.

4 Apr 2018

Higher protein intake may not benefit older adults

Regardless of whether an adult is young or old, male or female, their recommended dietary allowance for protein, set by the Institute of Medicine, is the same: 0.8-g/kg/day. Many experts and national organizations recommend dietary protein intakes greater than the recommended allowance to maintain and promote muscle growth in older adults.

2 Apr 2018

Natural dietary supplement tends to improve blood pressure and arterial health

Scientists have long known that restricting calories can fend off physiological signs of aging, with studies in fruit flies, roundworms, rodents and even people showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan.

29 Mar 2018

Phase I clinical trial of HIV vaccines to begin in the U.S.

A Phase I clinical trial testing the safety of vaccines that might have the potential to prevent HIV infection will begin this month at four sites in the United States, marking the latest step in a three-decade quest at UMass Medical School to harness the power of DNA vaccines in addressing a major global health threat.

28 Mar 2018

Antibiotic use linked to higher risk of severe viral disease in mice

People infected with West Nile virus can show a wide range of disease. Some develop life-threatening brain infections. Others show no signs of infection at all. One reason for the different outcomes may lie in the community of microbes that populate their intestinal tracts.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Menopausal hormone therapy taken soon after menopause may benefit the brain

Taking menopausal hormone therapy soon after menopause to relieve symptoms may also benefit the brain, according to a study published in the March 21, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

22 Mar 2018

Maternal intake of DHA supplement linked to higher fat-free body mass in children

University of Kansas researchers have reported that pregnant women who consumed a supplement of DHA (docosahexaenoic acid), a nutrient added to U.S. infant formulas since 2002, tend to have children with higher fat-free body mass at 5 years old.

21 Mar 2018

Diabetes medication reduces chance of late miscarriage, premature birth among women with PCOS

The oral diabetes medication metformin seems to reduce the chance of a late miscarriage and premature birth among women with polycystic ovary syndrome but does not affect their rate of developing gestational diabetes, a multicenter study finds.

20 Mar 2018

LSD reduces 'sense of self' - research

Dr Albert Hofmann, a Swiss chemist, first found the effects of LSD or lysergic acid diethylamide or “acid” on the psyche. It has been 75 years since his invention. Now new research finds deeper understanding of how this psychedelic chemical alters the perception and affects the brain.

19 Mar 2018

Placebo News and Research

One class of diabetes drug not associated with reduced risk of death

Antioxidant treatment may decrease cardiovascular risk in women with type 1 diabetes

Intranasal formulation of ketamine shows promise in rapid treatment of depression, suicidality

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Omega-3 supplements found to be ineffective in alleviating dry eye symptoms

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Intranasal spray shows promise for peanut allergy suppression

Ludwig scientists develop and test individualized ovarian cancer vaccine

Review identifies ethical issues in vitamin D research involving use of placebos

Study shows role of benzodiazepines in managing depression

Higher protein intake may not benefit older adults

Natural dietary supplement tends to improve blood pressure and arterial health

Phase I clinical trial of HIV vaccines to begin in the U.S.

Antibiotic use linked to higher risk of severe viral disease in mice

Antibody sweeps away Alzheimer's plaques in mice

Menopausal hormone therapy taken soon after menopause may benefit the brain

Maternal intake of DHA supplement linked to higher fat-free body mass in children

Diabetes medication reduces chance of late miscarriage, premature birth among women with PCOS

LSD reduces 'sense of self' - research

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