Transplant News and Research

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IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Hospital-acquired pneumonia and ventilator-associated pneumonia– which account for 20 to 25 percent of hospital-acquired infections – should be treated with shorter courses of antibiotics than they typically are, according to new guidelines released by the Infectious Diseases Society of America and American Thoracic Society and published in the journal Clinical Infectious Diseases.

14 Jul 2016

Gender matching may be beneficial to reduce risk of corneal transplant rejection and failure

A study of patients undergoing corneal transplants indicates that subtle differences between men and women may lead to poorer outcomes for a woman who has received a cornea from a male donor.

14 Jul 2016

New treatment approach may benefit relapsed post-transplant blood cancer patients

For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognosis.

13 Jul 2016

New, minimally invasive procedure may be effective for patients with FED

A new, minimally invasive procedure appears to be effective for many patients with Fuchs endothelial dystrophy (FED), a common eye disease, without the potential side effects and cost of the current standard of care, a cornea transplant.

13 Jul 2016

Two new studies find potential genetic cause and new treatment method for autoimmune diseases

The American Autoimmune Related Diseases Association, Inc. is spotlighting two new research studies originally reported in ScienceDaily.

13 Jul 2016

Innovative organ donation program allows living donors to donate kidney in advance

Gift certificate, layaway plan or voucher. Call it what you want, but an innovative organ donation program initiated at UCLA has started to spread to other transplant programs across the United States.

11 Jul 2016

OCA transplantation can be effective treatment option for active patients with knee cartilage injuries

For athletes and highly active patients who sustain cartilage injuries to their knee, an osteochondral allograft transplantation can be a successful treatment option, according to research presented today at the American Orthopaedic Society for Sports Medicine's Annual Meeting in Colorado Springs, CO.

11 Jul 2016

New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

When cells die, whether through apoptosis or necrosis, the DNA and other molecules found in those cells don't just disappear. They wind up in the blood stream, where degraded bits and pieces can be extracted.

8 Jul 2016

Transplant drug rapamycin may reduce nerve damage, neuropathic pain after spinal cord injury

New research in mice indicates that a drug commonly used to suppress the immune system in recipients of organ transplants may also reduce tissue damage and neuropathic pain after spinal cord injury. The findings are published in the Journal of Orthopaedic Research.

8 Jul 2016

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

A new study has found that the little-known member of the human herpesvirus family called HHV-6A infects the lining of the uterus in 43% of women with unexplained infertility but cannot be found in uterine lining of fertile women. The study was conducted by investigators at the University of Ferrara, Italy.

7 Jul 2016

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine.

6 Jul 2016

Emergency physicians encourage safe fireworks practices

Fireworks sales will be blazing across the country from now through the Fourth of July. As retailers begin their promotions, the Pennsylvania Academy of Ophthalmology, the Pennsylvania College of Emergency Physicians, and the Pennsylvania Medical Society join the American Academy of Ophthalmology in shining light on the explosive fact: fireworks injuries cause approximately 10,000 visits to the emergency room each year, according to the data from the U.S. Consumer Product Safety Commission.

4 Jul 2016

New strategy treats fatal autoimmune disease without outward off-target effects

In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system.

4 Jul 2016

Surgeons outline complete face transplant procedure in facial burn patients

Last year, the most extensive clinical face transplant to date was successfully carried out at NYU Langone Medical Center.

30 Jun 2016

Study highlights role of CMV in patients with leukemia after bone marrow transplantation

Recent studies on a small number of patients with leukemia treated with bone marrow transplantation have suggested that the presence of the common cytomegalovirus (CMV) in patients or their donors may protect against relapse or even death after the transplant.

29 Jun 2016

LIF-treated muscle stem cells show promise in treatment of muscular dystrophy

Satellite cells are stem cells found in skeletal muscles. While transplantation of such muscle stem cells can be a potent therapy for degenerative muscle diseases such as Duchenne muscular dystrophy, these cells tend to lose their transplantation efficiency when cultured in vitro.

28 Jun 2016

Elevated troponin I should not rule out donor hearts

Donor cardiac troponin I level is not associated with intermediate-term mortality, cardiac allograft vasculopathy or primary graft failure in patients receiving heart transplants, US researchers report.

28 Jun 2016

Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Using virtual tissue technology, researchers at Indiana University have identified a potential new drug target in the fight against polycystic kidney disease, an illness with no effective FDA-approved treatment that affects 200,000 people per year in the United States.

28 Jun 2016

Researchers receive grant to improve quality of donor limb, tissue for transplant

A Case Western Reserve University School of Medicine faculty member has received $998,500 from the U.S. Department of Defense to develop a new approach to improve the quality and quantity of limbs and tissues obtained from brain dead organ donors.

27 Jun 2016

Eye donations: what stops people? An interview with Rory Passmore

Despite a shortage of corneas for transplant purposes, our new research reveals that eyes are the one body part we are least likely to donate.

27 Jun 2016

Transplant News and Research

IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Gender matching may be beneficial to reduce risk of corneal transplant rejection and failure

New treatment approach may benefit relapsed post-transplant blood cancer patients

New, minimally invasive procedure may be effective for patients with FED

Two new studies find potential genetic cause and new treatment method for autoimmune diseases

Innovative organ donation program allows living donors to donate kidney in advance

OCA transplantation can be effective treatment option for active patients with knee cartilage injuries

New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

Transplant drug rapamycin may reduce nerve damage, neuropathic pain after spinal cord injury

HHV-6A human herpesvirus infects uterus lining of women with unexplained infertility

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Emergency physicians encourage safe fireworks practices

New strategy treats fatal autoimmune disease without outward off-target effects

Surgeons outline complete face transplant procedure in facial burn patients

Study highlights role of CMV in patients with leukemia after bone marrow transplantation

LIF-treated muscle stem cells show promise in treatment of muscular dystrophy

Elevated troponin I should not rule out donor hearts

Virtual tissue technology helps identify new drug target to combat polycystic kidney disease

Researchers receive grant to improve quality of donor limb, tissue for transplant

Eye donations: what stops people? An interview with Rory Passmore

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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