Cell News and Research

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Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

A recent study led by researchers in Texas A&M University's department of nutrition and food science shows how a novel regulatory mechanism serves as an important biomarker for the development of diabetes, as well as a potential therapeutic target for its prevention.

20 Dec 2018

Researchers discover cost-efficient, accurate method to examine effectiveness of cardiomyocytes

A faster, more cost-efficient, and more accurate method of examining the effectiveness of human pluripotent stem-cell-derived cardiac muscle cells has been discovered, according to researchers from Penn State.

20 Dec 2018

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

The importance of research into the role of the immune system in the development and therapy of oncological diseases was emphasized by the Royal Swedish Academy, which recently named James Allison and Tasuku Honjo recipients of the 2018 Nobel Prize in Physiology or Medicine for launching an effective new way to attack cancer by treating the immune system rather than the tumor.

20 Dec 2018

Review highlights calcium handling mechanisms involved in reperfusion injury

Stroke and myocardial infarction (MI) are a significant cause of death and disability worldwide. However, over the past several decades because of advances in medicines (thrombolytic agents, antiplatelet drugs, beta blockers, and angiotensin converting enzyme inhibitors) and approaches to restore tissue perfusion (percutaneous coronary intervention and cardiopulmonary bypass), the mortality of MI has declined dramatically.

20 Dec 2018

Stress related pathway instrumental in controlling function of immune cells

The immune system is composed of a wide range of different immune cells each with dedicated functions. Natural killer T cells form a specialized immune cell that protects against a variety of diseases such as cancer, autoimmunity, metabolic disease or certain infections such as Lyme disease.

20 Dec 2018

European scientists aim to identify causes of dementia

Dementia is common to a variety of neurodegenerative diseases such as Alzheimer's disease, Parkinson disease and Down syndrome. This common symptom is one of the major causes of disability and dependency among older people.

19 Dec 2018

Researchers synthesize new compound that inhibits replication of hepatitis C virus

A new compound that inhibits the replication of hepatitis C virus in several stages of its lifecycle - and is also capable of acting on bacteria, fungi and cancer cells - has been synthesized by researchers at São Paulo State University in Brazil.

19 Dec 2018

Viral hepatitis: Liver failure caused by defects in the vascular system

In severe cases, a viral hepatitis infection can result in liver failure. A team from the Technical University of Munich has now discovered how this occurs: by immune cells attacking cells in the vascular system, which disrupts the organ's blood and nutrient supply.

19 Dec 2018

Study investigates why mammals' sense of smell deteriorates in old age

As mammals age, their sense of smell deteriorates. In a study published in the journal 'Cell Reports', an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why this is the case.

19 Dec 2018

GABA cells help fight alcohol dependence, study finds

Scientists of the Higher School of Economics, Indiana University, and École normale supérieure clarified how alcohol influences the dopamine and inhibitory cells in the midbrain that are involved in the reward system and the formation of dependency on addictive drugs.

19 Dec 2018

Researchers uncover genes that play a key role in the inactivation of X chromosomes

In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference?

19 Dec 2018

Galectins play a key role in the degeneration of cartilage in osteoarthritis

A network of carbohydrate binding proteins - so-called galectins - plays an important role in the degeneration of cartilage in osteoarthritis.

19 Dec 2018

Personalization techniques give a new lease of life to anticancer vaccines

Anticancer vaccines have gained a new lease of life with techniques to personalise them to individual patients.

19 Dec 2018

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

HPV discovery could lead to new treatments for cervical cancer

Researchers at the University of Virginia School of Medicine have made a discovery about human papillomavirus that could lead to new treatments for cervical cancer and other cancers caused by the virus.

19 Dec 2018

University of Marburg team celebrates success at 2018 IGEM Giant Jamboree competition

At the 2018 iGEM Gaint Jamboree, the team of the University of Marburg won the Grand Prize in the overgraduate section with their project “VibriGens – Accelerating SynBio”. At the end of October the team received its award in Boston, USA.

From BMG LABTECH GmbH 19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

Study reveals how stem cells can be induced to differentiate into various ocular lineages

The discovery of pluripotent stem cells, which have the ability to differentiate into the huge range of different cell lineages that make up the human body, signaled the start of a new era in biological science and medicine. Although we are also now able to reprogram regular cells to exhibit this pluripotency, we still have much to learn about the different cues that lead such cells towards a particular cell fate, including the cells that make up the eye.

19 Dec 2018

Hepatitis C drug can eliminate chikungunya, yellow fever virus

A study performed at the University of São Paulo's Biomedical Science Institute (ICB-USP) in Brazil shows that sofosbuvir, a drug used to treat chronic hepatitis C, is capable of eliminating chikungunya virus and yellow fever virus.

19 Dec 2018

Potential combination therapy against rare disease of the bone marrow could improve treatment

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking.

19 Dec 2018

Cell News and Research

Study shows how a novel regulatory mechanism serves as key biomarker for diabetes

Researchers discover cost-efficient, accurate method to examine effectiveness of cardiomyocytes

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

Review highlights calcium handling mechanisms involved in reperfusion injury

Stress related pathway instrumental in controlling function of immune cells

European scientists aim to identify causes of dementia

Researchers synthesize new compound that inhibits replication of hepatitis C virus

Viral hepatitis: Liver failure caused by defects in the vascular system

Study investigates why mammals' sense of smell deteriorates in old age

GABA cells help fight alcohol dependence, study finds

Researchers uncover genes that play a key role in the inactivation of X chromosomes

Galectins play a key role in the degeneration of cartilage in osteoarthritis

Personalization techniques give a new lease of life to anticancer vaccines

Active ingredient in eye drops shows promise for treating aggressive blood cancer

HPV discovery could lead to new treatments for cervical cancer

University of Marburg team celebrates success at 2018 IGEM Giant Jamboree competition

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Study reveals how stem cells can be induced to differentiate into various ocular lineages

Hepatitis C drug can eliminate chikungunya, yellow fever virus

Potential combination therapy against rare disease of the bone marrow could improve treatment

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